Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Pratirodh Koirala"'
Autor:
Irena Adkins, Emily Kuiper, Kathleen Whiteman, Daniel Garafola, Pratirodh Koirala, Shannon Smith, Klara Danova, Ekaterina Simonova, Lenka Palova Jelinkova, Amy Jensen-Smith
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/78c1b034b1264883b2328f8ae32d7d19
Autor:
Wan-Xin Peng, Pratirodh Koirala, Huaixiang Zhou, Jiahong Jiang, Ziqiang Zhang, Liu Yang, Yin-Yuan Mo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Abstract Selective estrogen receptor modulators (SERMs) such as tamoxifen have proven to be effective in the treatment of estrogen receptor (ER) positive breast cancer. However, a major obstacle for such endocrine therapy is estrogen independent grow
Externí odkaz:
https://doaj.org/article/92ea29efb17a48399b9e5fa8f6e03dea
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The function of many human long non-coding RNAs (lncRNAs) is still undetermined. Here, the authors setup a gain of function CRISPR-based screen and identify a lncRNA that positively regulates AKT activity by interacting with the RNA helicase DHX9 res
Externí odkaz:
https://doaj.org/article/79733fb316b948ea870d4afb62415e88
Autor:
John Hinds, Sujatha Muralidharan, Ann Ranger, Jennifer Coccia, Thomas Giordano, Emily Kuiper, Pratirodh Koirala
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
Molecular Therapy. 31:909-910
Publikováno v:
Molecular Therapy. 31:1499
Publikováno v:
Molecular Therapy. 28:9-18
Large bodies of studies have shown that the CRISPR/Cas9-based library screening is a very powerful tool for the identification of gene functions. However, most of these studies have focused on protein-coding genes, and, furthermore, very few studies
Autor:
Liu Yang, Wanxin Peng, Yin-Yuan Mo, Ziqiang Zhang, Pratirodh Koirala, Huaixiang Zhou, Jiahong Jiang
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Selective estrogen receptor modulators (SERMs) such as tamoxifen have proven to be effective in the treatment of estrogen receptor (ER) positive breast cancer. However, a major obstacle for such endocrine therapy is estrogen independent growth, leadi
Publikováno v:
Oncogene
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered through functional genomics studies. Importantly, lncRNAs have been shown, in many cases, to function as master regulators for gene expression and thus, they can
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Despite the overwhelming number of human long non-coding RNAs (lncRNAs) reported so far, little is known about their physiological functions for the majority of them. The present study uses a CRISPR/Cas9-based synergistic activation mediator (SAM) sy