Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pratima, Saini"'
Autor:
Hao Nie, Pratima Saini, Taito Miyamoto, Liping Liao, Rafal J. Zielinski, Heng Liu, Wei Zhou, Chen Wang, Brennah Murphy, Martina Towers, Tyler Yang, Yuan Qi, Toshitha Kannan, Andrew Kossenkov, Hiroaki Tateno, Daniel T. Claiborne, Nan Zhang, Mohamed Abdel-Mohsen, Rugang Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Aberrant glycosylation is a crucial strategy employed by cancer cells to evade cellular immunity. However, it’s unclear whether homologous recombination (HR) status-dependent glycosylation can be therapeutically explored. Here, we show tha
Externí odkaz:
https://doaj.org/article/f6c6df012ec140a7a4fd2deb6a11201f
Autor:
Pratima Saini, Opeyemi S. Adeniji, Devivasha Bordoloi, Jennifer Kinslow, Jeff Martinson, Danielle M. Parent, Kai Ying Hong, Jane Koshy, Abhijeet J. Kulkarni, Netanel F. Zilberstein, Robert A. Balk, James N. Moy, Leila B. Giron, Russell P. Tracy, Ali Keshavarzian, Kar Muthumani, Alan Landay, David B. Weiner, Mohamed Abdel-Mohsen
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection alters the immunological profiles of natural killer (NK) cells. However, whether NK antiviral functions are impaired during severe coronavirus disease 2019 (COVID-19) and
Externí odkaz:
https://doaj.org/article/9b30c013c37148c591071bf5b0975101
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104354- (2022)
Summary: Siglecs are a family of emerging glyco-immune checkpoints. Inhibiting them can enhance the functions of several types of immune cells, whereas engaging them can reduce hyper-inflammation and hyper-activation of immune functions. Siglec-sialo
Externí odkaz:
https://doaj.org/article/0925d9ecf0974676ba6101e034387f5e
Publikováno v:
Biochemical and Biophysical Research Communications. 506:60-65
Investigations on the structure and functional roles of glycosylation - an intricate, complex, and dynamic post translational modification on proteins - in biological processes has been a challenging task. Glycan modifications vary depending on the s
Autor:
Vandita, Dwivedi, Pratima, Saini, Anam, Tasneem, Kavita, Agarwal, Srinivasa-Gopalan, Sampathkumar
Publikováno v:
Biochemical and biophysical research communications. 506(1)
Investigations on the structure and functional roles of glycosylation - an intricate, complex, and dynamic post translational modification on proteins - in biological processes has been a challenging task. Glycan modifications vary depending on the s