Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pratikkumar Rathod"'
Autor:
Basant Dhital, Philip Durlik, Pratikkumar Rathod, Farhana Gul-E-Noor, Zhixiao Wang, Cheng Sun, Emmanuel J. Chang, Boris Itin, Gregory S. Boutis
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 172-177 (2017)
Elastic fibers, a major component of the extracellular matrix of the skin, are often exposed to ultraviolet (UV) radiation throughout mammalian life. We report on an in vitro study of the alterations in bovine nuchal ligament elastic fibers resulting
Externí odkaz:
https://doaj.org/article/ed38179792f7497d992f3bead60c00c3
Autor:
Karl R. Fath, Dibyendu Dana, Jeremy Garcia, Sanjai K. Pathak, Pratikkumar Rathod, Laura Joo, Daniel A. Novoa, Suneeta Paroly, Emmanuel J. Chang, Ashif I. Bhuiyan
Publikováno v:
Bioorganic Chemistry. 85:505-514
Human cathepsin L is a ubiquitously expressed endopeptidase and is known to play critical roles in a wide variety of cellular signaling events. Its overexpression has been implicated in numerous human diseases, including highly invasive forms of canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196198e6bb2c1b2fc560786f649308d7
https://doi.org/10.1016/j.bioorg.2019.02.032
https://doi.org/10.1016/j.bioorg.2019.02.032
Autor:
Faiza Rafi, Karl R. Fath, Anna A. Dickson, Tuhin Das, Guoshen Li, Gopal Subramaniam, Sarbani Ghoshal, Sanjai K. Pathak, Pratikkumar Rathod, Dibyendu Dana, Suneeta Paroly, Ashif I. Bhuiyan, Emmanuel J. Chang
Publikováno v:
Bioorganic Chemistry. 117:105463
Human cathepsin B is a cysteine-dependent protease whose roles in both normal and diseased cellular states remain yet to be fully delineated. This is primarily due to overlapping substrate specificities and lack of unambiguously annotated physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bef6f0f68d423d40501e60e4599276b
https://doi.org/10.1016/j.bioorg.2021.105463
https://doi.org/10.1016/j.bioorg.2021.105463
Autor:
Gregory S. Boutis, Cheng Sun, Boris Itin, Philip Durlik, Basant Dhital, Emmanuel J. Chang, Pratikkumar Rathod, Zhixiao Wang, Farhana Gul-E-Noor
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 172-177 (2017)
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 172-177 (2017)
Elastic fibers, a major component of the extracellular matrix of the skin, are often exposed to ultraviolet (UV) radiation throughout mammalian life. We report on an in vitro study of the alterations in bovine nuchal ligament elastic fibers resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7ce7df71b2063c1e615930c3e3ab8b
https://doi.org/10.1016/j.bbrep.2017.04.002
https://doi.org/10.1016/j.bbrep.2017.04.002
Autor:
Pratikkumar Rathod, Gregory S. Boutis, Keith Downing, Shari Hirsch, Yakov Landau, Basant Dhital, Farhana Gul-E-Noor, Emmanuel J. Chang
Publikováno v:
Arch Biochem Biophys
Female reproductive tissues undergo significant alterations during pregnancy, which may compromise the structural integrity of extracellular matrix proteins. Here, we report on modifications of elastic fibers, which are primarily composed of elastin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b2f92ea43f364c446834bf5afa61ae
https://europepmc.org/articles/PMC6529287/
https://europepmc.org/articles/PMC6529287/
Autor:
Gregory S. Boutis, Jong I Lee, Philip Durlik, Manjeet Kaur, Pratikkumar Rathod, Marissa E Louis, Basant Dhital, Kevin J. Mark, Emmanuel J. Chang, Hsin-Pin Ho
Publikováno v:
Analytical and bioanalytical chemistry. 410(26)
Desmosine (Des) and Isodesmosine (Isodes), cross-linking amino acids in the biomolecule elastin, may be used as biomarkers for various pathological conditions associated with elastin degradation. The current study presents a novel approach to quantif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97b76204f8226e89bb163ce553090a5
https://pubmed.ncbi.nlm.nih.gov/30062515
https://pubmed.ncbi.nlm.nih.gov/30062515
Autor:
Dibyendu Dana, Jin Leng, Emmanuel J. Chang, Sherida Rahaman, Hsin Pin Ho, Mathias Lichterfeld, Sanjai Kumar, Kevin J. Mark, Pratikkumar Rathod, Marissa E Louis, Christine K. Tada
Publikováno v:
Rapid Communications in Mass Spectrometry. 28:2681-2689
RATIONALE Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry combined with isotope labeling methods are effective for protein and peptide quantification, but limited in their multiplexing capacity, cost-effectiveness and dynamic ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684bc975a6d12b4501d3849e07c5ee06
https://doi.org/10.1002/rcm.7063
https://doi.org/10.1002/rcm.7063
Autor:
Ranjith K. Gamage, Nisar Afzal, Sanjai Kumar, Anibal R. Davalos, Kevin J. Mark, Susan A. Rotenberg, Emmanuel J. Chang, Yuriy Zavlanov, Suneeta Paroly, Juliana Huestis, Shatarupa De, Gopal Subramaniam, Dibyendu Dana, Pratikkumar Rathod
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:2975-2987
Cysteine cathepsins are an important class of enzymes that coordinate a variety of important cellular processes, and are implicated in various types of human diseases. However, small molecule inhibitors that are cell-permeable and non-peptidyl in nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a477ab015c71279a2437c2d9995d6931
https://doi.org/10.1016/j.bmc.2013.03.062
https://doi.org/10.1016/j.bmc.2013.03.062
Autor:
Hsin-Pin, Ho, Pratikkumar, Rathod, Marissa, Louis, Christine K, Tada, Sherida, Rahaman, Kevin J, Mark, Jin, Leng, Dibyendu, Dana, Sanjai, Kumar, Mathias, Lichterfeld, Emmanuel J, Chang
Publikováno v:
Rapid communications in mass spectrometry : RCM. 28(24)
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry combined with isotope labeling methods are effective for protein and peptide quantification, but limited in their multiplexing capacity, cost-effectiveness and dynamic range. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::846d365c9b0648d1dda300d16d3f3382
https://pubmed.ncbi.nlm.nih.gov/25380489
https://pubmed.ncbi.nlm.nih.gov/25380489
Autor:
Shatarupa De, Nisar Afzal, Dibyendu Dana, Sanjai Kumar, Gopal Subramaniam, Suneeta Paroly, Daniel A. Novoa, Ravi S. Lankalapalli, Susan A. Rotenberg, Emmanuel J. Chang, Anibal R. Davalos, Viviana M. Torres, Pratikkumar Rathod
Publikováno v:
Chemical communications (Cambridge, England). 50(74)
A hybrid-design approach is undertaken to develop a highly potent and selective inhibitor of human cathepsin L. Studies involving human breast carcinoma MDA-MB-231 cells establish that this inhibitor can successfully block intracellular cathepsin L a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5d718f21a931b599848aee0c9132fd
https://pubmed.ncbi.nlm.nih.gov/25089379
https://pubmed.ncbi.nlm.nih.gov/25089379