Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pratik V, Devasthale"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:3119-3124
The synthesis of carbocyclic molecules containing functional groups capable of interacting with appropriate binding sites in certain metalloproteinases is described. Preliminary biological evaluation reveals modest inhibitory activity for a thioether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166b7fa9b84fab687f5ac540a32ea57a
https://doi.org/10.1016/s0960-894x(97)10171-8
https://doi.org/10.1016/s0960-894x(97)10171-8
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:2201-2206
A novel series of chain-extended, pseudo C2 symmetric 1,5-diaminoalcohol analogs was designed and synthesized using an efficient nitroaldol condensation mediated by triethylsilyl triflate and TBAF.xH2O. Prototypical acyclic compounds harboring a cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9246ca09bea0db114cb5937a25caf85
https://doi.org/10.1016/0960-894x(96)00392-7
https://doi.org/10.1016/0960-894x(96)00392-7
Publikováno v:
Tetrahedron Letters. 37:987-990
Condensations of N,N-dibenzyl α-amino aldehydes with nitroalkanes mediated by tetrabutylammonium fluoride proceed in excellent yields and selectivites. This affords rapid and stereoselective access to acyclic molecules containing differentiated nitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::110bba92c41951e1b856b742506dfbaf
https://doi.org/10.1016/0040-4039(95)02359-3
https://doi.org/10.1016/0040-4039(95)02359-3
Publikováno v:
ChemInform. 29
The synthesis of carbocyclic molecules containing functional groups capable of interacting with appropriate binding sites in certain metalloproteinases is described. Preliminary biological evaluation reveals modest inhibitory activity for a thioether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3623909680c2462888b96348c0935ca9
https://doi.org/10.1002/chin.199817216
https://doi.org/10.1002/chin.199817216
Autor:
Pratik V, Devasthale, Sean, Chen, Yoon, Jeon, Fucheng, Qu, Denis E, Ryono, Wei, Wang, Hao, Zhang, Lin, Cheng, Dennis, Farrelly, Rajasree, Golla, Gary, Grover, Zhengping, Ma, Lisa, Moore, Ramakrishna, Seethala, Wei, Sun, Arthur M, Doweyko, Gamini, Chandrasena, Paul, Sleph, Narayanan, Hariharan, Peter T W, Cheng
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(8)
A novel series of potent dual agonists of PPARalpha and PPARgamma, the alkoxybenzylglycines, was identified and explored using a solution-phase library approach. The synthesis and structure-activity relationships of this series of dual PPARalpha/gamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba9ce72890feecec8742fc4d1948e12b
https://pubmed.ncbi.nlm.nih.gov/17292606
https://pubmed.ncbi.nlm.nih.gov/17292606