Výsledky vyhledávání - "Pratik P. Vikhe"

Mutation in Fbxo11 Leads to Altered Immune Cell Content in Jeff Mouse Model of Otitis Media

Autor: Gurpreet Bharj, Pratik P. Vikhe, Steve D. M. Brown, Hilda Tateossian, Derek W. Hood

Publikováno v: Frontiers in Genetics, Vol 11 (2020)

The Jeff mouse mutant carries a mutation in the F-box only 11 gene (Fbxo11) and heterozygous animals display conductive deafness due to the development of otitis media (OM). The Fbxo11 locus is also associated with chronic otitis media with effusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac60bb7bbb11b1ac8c33b67b35ea31b6
https://www.frontiersin.org/article/10.3389/fgene.2020.00050/full

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Cellular Immune Response against Nontypeable

Autor: Pratik P, Vikhe, Tom, Purnell, Steve D M, Brown, Derek W, Hood

Publikováno v: Infection and Immunity

Nontypeable Haemophilus influenzae (NTHi) is a major pathogen causing acute otitis media (AOM). The pathology of AOM increases during long-term infection in the middle ear (ME), but the host cellular immune response to bacterial infection in this inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::046b25d18e90e6441838d8ea2bc28744
https://pubmed.ncbi.nlm.nih.gov/31548315

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The

Autor: Oana, Kubinyecz, Pratik P, Vikhe, Thomas, Purnell, Steve D M, Brown, Hilda, Tateossian

Publikováno v: Frontiers in Genetics

Chronic otitis media (OM) is the most common cause of hearing loss worldwide, yet the underlying genetics and molecular pathology are poorly understood. The mouse mutant Jeff is a single gene mouse model for OM identified from a deafness screen as pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c01bc113fc54dafe14f30ae403b7f07e
https://pubmed.ncbi.nlm.nih.gov/32508883

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Mutation in

Autor: Pratik P, Vikhe, Hilda, Tateossian, Gurpreet, Bharj, Steve D M, Brown, Derek W, Hood

Publikováno v: Frontiers in Genetics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4fae414e2215a094a53334e3b597ff3
https://pubmed.ncbi.nlm.nih.gov/32117459

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Cellular content plays a crucial role in Non‐typeableHaemophilus influenzaeinfection of preinflamedJunbomouse middle ear

Autor: Derek W. Hood, Pratik P. Vikhe, Tom Purnell, Steve D.M. Brown

Publikováno v: Cellular Microbiology

Non‐typeable Haemophilus influenzae (NTHi) is a major pathogen causing acute otitis media (AOM). The relationship between the cellular content of the middle ear fluid (MEF) during AOM and infection of NTHi is poorly understood. Using the Junbo mous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb995dea7ec999242246e82659ef24e5
https://doi.org/10.1111/cmi.12960

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Akademický článek

Pleiotropic brain function of whirlin identified by a novel mutation.

Autor: Aguilar C; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Williams D; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK.; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Kurapati R; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Bains RS; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Mburu P; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Parker A; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Williams J; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Concas D; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Tateossian H; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Haynes AR; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Banks G; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Vikhe P; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Heise I; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Hutchison M; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Atkins G; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Gillard S; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Starbuck B; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Oliveri S; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Blake A; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Sethi S; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Kumar S; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Bardhan T; School of Biosciences, University of Sheffield, Sheffield, South Yorkshire S10 2TN, UK., Jeng JY; School of Biosciences, University of Sheffield, Sheffield, South Yorkshire S10 2TN, UK., Johnson SL; School of Biosciences, University of Sheffield, Sheffield, South Yorkshire S10 2TN, UK., Corns LF; School of Biosciences, University of Sheffield, Sheffield, South Yorkshire S10 2TN, UK., Marcotti W; School of Biosciences, University of Sheffield, Sheffield, South Yorkshire S10 2TN, UK.; Neuroscience Institute, University of Sheffield, Sheffield, South Yorkshire S10 2TN, UK., Simon M; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Wells S; Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Potter PK; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK., Lad HV; MRC Harwell Institute, Mammalian Genetics Unit, Harwell Campus, Didcot, Oxfordshire OX11 0RD, UK.

Publikováno v: IScience [iScience] 2024 Jun 04; Vol. 27 (7), pp. 110170. Date of Electronic Publication: 2024 Jun 04 (Print Publication: 2024).

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Akademický článek

Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques.

Autor: Lim SY; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Lee J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Osuna CE; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Vikhe P; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Schalk DR; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA., Chen E; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Fray E; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Kumar M; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Schultz-Darken N; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA., Rakasz E; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA., Capuano S; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA., Ladd RA; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA., Gil HM; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA., Evans DT; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53715, USA., Jeng EK; Altor Biosciences, Miramar, FL 33027, USA., Seaman M; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Martin M; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Van Dorp C; Los Alamos National Laboratory, Los Alamos, NM 87545, USA., Perelson AS; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.; Santa Fe Institute, Santa Fe, NM 87501, USA., Wong HC; Altor Biosciences, Miramar, FL 33027, USA., Siliciano JD; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Siliciano R; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Safrit JT; ImmunityBio, Culver City, CA 90232, USA., Nixon DF; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Soon-Shiong P; ImmunityBio, Culver City, CA 90232, USA., Nussenzweig M; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA., Whitney JB; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Department of Biology, Boston College, Chestnut Hill, MA 02467, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Mar 08; Vol. 383 (6687), pp. 1104-1111. Date of Electronic Publication: 2024 Feb 29.

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