Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Pratiek N. Matkar"'
Autor:
Shweta Singh, Hien Nguyen, David Michels, Hannah Bazinet, Pratiek N. Matkar, Zongyi Liu, Lilian Esene, Mohamed Adam, Antoinette Bugyei‐Twum, Elizabeth Mebrahtu, Jameela Joseph, Mehroz Ehsan, Hao H. Chen, Mohammad Qadura, Krishna K. Singh
Publikováno v:
Physiological Reports, Vol 8, Iss 13, Pp n/a-n/a (2020)
Abstract Mutations in the tumor suppressor gene BRCA2 (BReast CAncer susceptibility gene 2) predispose carriers to breast, ovarian, and other cancers. In response to DNA damage, BRCA2 participates in homology‐directed DNA damage repair to maintain
Externí odkaz:
https://doaj.org/article/f240653a602846eeb921ff5653c52f8d
Autor:
Shamini Murugavel, Antoinette Bugyei-Twum, Pratiek N. Matkar, Husain Al-Mubarak, Hao H. Chen, Mohamed Adam, Shubha Jain, Tanya Narang, Rawand M. Abdin, Mohammad Qadura, Kim A. Connelly, Howard Leong-Poi, Krishna K. Singh
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, is a widely used anticonvulsant drug that is currently undergoing clinical evaluation for anticancer therapy due to its anti-angiogenic potential. Endothelial cells (ECs) can transition int
Externí odkaz:
https://doaj.org/article/68258d06355b49dea36272244efe19f1
Autor:
Azadeh Mofid, Nadav S. Newman, Paul J. H. Lee, Cynthia Abbasi, Pratiek N. Matkar, Dmitriy Rudenko, Michael A. Kuliszewski, Hao H. Chen, Kolsoom Afrasiabi, James N. Tsoporis, Anthony O. Gramolini, Kim A. Connelly, Thomas G. Parker, Howard Leong‐Poi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 2 (2017)
BackgroundCardiomyocyte‐specific transgenic mice overexpressing S100A6, a member of the family of EF‐hand calcium‐binding proteins, develop less cardiac hypertrophy, interstitial fibrosis, and myocyte apoptosis after permanent coronary ligation
Externí odkaz:
https://doaj.org/article/92df0ac64eb74894904427e941a361fd
Autor:
Krishna K. Singh, Pratiek N. Matkar, Adrian Quan, Laura-Eve Mantella, Hwee Teoh, Mohammed Al-Omran, Subodh Verma
Publikováno v:
International Journal of Vascular Medicine, Vol 2016 (2016)
Objective. To evaluate the relationship between TGFβ signaling and endothelial lncRNA expression. Methods. Human umbilical vein endothelial cell (HUVECs) lncRNAs and mRNAs were profiled with the Arraystar Human lncRNA Expression Microarray V3.0 afte
Externí odkaz:
https://doaj.org/article/7396a5f1592b451f8a6b7ed439eb61bf
Publikováno v:
Biomolecules, Vol 7, Iss 4, p 74 (2017)
Angiogenesis, the formation of new blood vessels from pre-existing ones is a biological process that ensures an adequate blood flow is maintained to provide the cells with a sufficient supply of nutrients and oxygen within the body. Numerous soluble
Externí odkaz:
https://doaj.org/article/154dfaec5b1142feb89bf43cfdbe7e61
Autor:
Hao H Chen, Jameela Joseph, Hannah Bazinet, Mohammad Qadura, David Michels, Lillian Esene, Zongyi Liu, Howard Leong-Poi, Mehroz Ehsan, Jean-Francois Desjardins, Elizabeth Mebrahtu, Pratiek N. Matkar, Hien Nguyen, Kim A. Connelly, Shweta Singh, Antoinette Bugyei-Twum, Mohamed Adam, Krishna K. Singh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Intraflagellar transport protein 88 (Ift88) is required for ciliogenesis and shear stress-induced dissolution of cilia in embryonic endothelial cells coincides with endothelial-to-mesenchymal transition (EndMT) in the developing heart. EndMT is also
Autor:
Pratiek N. Matkar, Jameela Joseph, Krishna K. Singh, Zongyi Liu, Mohammad Qadura, Hao H Chen, Hannah Bazinet, Lilian Esene, Mehroz Ehsan, Hien Nguyen, Antoinette Bugyei-Twum, Shweta Singh, Elizabeth Mebrahtu, David Michels, Mohamed Adam
Publikováno v:
Physiological Reports, Vol 8, Iss 13, Pp n/a-n/a (2020)
Physiological Reports
Physiological Reports
Mutations in the tumor suppressor gene BRCA2 (BReast CAncer susceptibility gene 2) predispose carriers to breast, ovarian, and other cancers. In response to DNA damage, BRCA2 participates in homology‐directed DNA damage repair to maintain genome st
Autor:
David W. Hedley, Pratiek N. Matkar, Michael A. Kuliszewski, Howard Leong-Poi, Yu Jin Kim, Krishna K. Singh, Dmitriy Rudenko, Gerald J. Prud'homme
Publikováno v:
Oncotarget
// Pratiek N. Matkar 1, 6 , Krishna Kumar Singh 2, 3, 6 , Dmitriy Rudenko 1 , Yu Jin Kim 1 , Michael A. Kuliszewski 1 , Gerald J. Prud’homme 4 , David W. Hedley 5 , Howard Leong-Poi 1, 6 1 Division of Cardiology, Keenan Research Centre for Biomedic
Publikováno v:
Journal of Controversies in Biomedical Research, Vol 1, Iss 1, Pp 51-66 (2015)
Marfan syndrome (MFS) is a relatively rare disease of the connective tissue that affects several organs of the body. Cardiovascular abnormalities such as aortic root dilatation and mitral valve prolapse are the two main life-threatening complications
Autor:
Michael A. Kuliszewski, Pratiek N. Matkar, Nathan C Roth, Howard Leong-Poi, P.J. Lee, Wei J Cao, Joshua D. Rosenblat, Dmitriy Rudenko, Christine Liao
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:2401-2411
Objective— MicroRNAs are involved in many critical functions, including angiogenesis. Ultrasound-targeted microbubble destruction (UTMD) is a noninvasive technique for targeted vascular transfection of plasmid DNA and may be well suited for proangi