Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pratibha Potla"'
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 3, Pp 100479- (2024)
Objective: Obesity is a leading risk factor for both the incidence and progression of osteoarthritis (OA). Omic technologies, including transcriptomics and metabolomics are capable of identifying RNA and metabolite profiles in tissues and biofluids o
Externí odkaz:
https://doaj.org/article/d78576ba3141443cbd77eec53dcdbaaf
Autor:
Joshua Antunes, Ramés Salcedo-Jiménez, Starlee Lively, Pratibha Potla, Nathalie Coté, Marie-Soleil Dubois, Judith Koenig, Mohit Kapoor, Jonathan LaMarre, Thomas Gadegaard Koch
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297303 (2024)
Osteoarthritis (OA) is a leading cause of lameness in horses with no effective disease-modifying treatment and challenging early diagnosis. OA is considered a disease of the joint involving the articular cartilage, subchondral bone, synovial membrane
Externí odkaz:
https://doaj.org/article/c84e02d8789442449379633477327088
Autor:
Starlee Lively, Marie Milliot, Pratibha Potla, Osvaldo Espin-Garcia, Mehdi Layeghifard, Kala Sundararajan, Helal Endisha, Akihiro Nakamura, Anthony V. Perruccio, Christian Veillette, Mohit Kapoor, Y. Raja Rampersaud
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 3, Pp 100283- (2022)
Purpose: Up to 30% of spine facet osteoarthritis patients with lumbar spinal stenosis (SF-OA + LSS) have little to no improvement in their pain after surgery. Lack of meaningful improvement in pain following surgery provides a unique opportunit
Externí odkaz:
https://doaj.org/article/4de197ee90d8442d8c929c816a3f1b97
Autor:
Shabana Amanda Ali, Osvaldo Espin-Garcia, Andy K. Wong, Pratibha Potla, Chiara Pastrello, Madison McIntyre, Starlee Lively, Igor Jurisica, Rajiv Gandhi, Mohit Kapoor
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 14 (2022)
Introduction: The objective of this study is to identify circulating microRNAs that distinguish fast-progressing radiographic knee osteoarthritis (OA) in the Osteoarthritis Initiative cohort by applying microRNA-sequencing. Methods: Participants with
Externí odkaz:
https://doaj.org/article/e2795f42f72c467581625bc5655e1a28
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 3, Iss 1, Pp 100131- (2021)
The rapid expansion of Next Generation Sequencing (NGS) data availability has made exploration of appropriate bioinformatics analysis pipelines a timely issue. Since there are multiple tools and combinations thereof to analyze any dataset, there can
Externí odkaz:
https://doaj.org/article/0486d27945a24ed5807cca46d71bcfe7
Autor:
Poulami Datta, Rajiv Gandhi, Sayaka Nakamura, Starlee Lively, Evgeny Rossomacha, Pratibha Potla, Konstantin Shestopaloff, Helal Endisha, Chiara Pastrello, Igor Jurisica, Jason S. Rockel, Mohit Kapoor
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 3, Pp 100080- (2020)
Summary: Objective: Osteoarthritis (OA) is a degenerative joint disease with no approved disease modifying therapy. The enzyme autotaxin (ATX) converts lysophoshatidylcholine analogues to lysophosphatidic acid. Systemic inhibition of ATX reduces pain
Externí odkaz:
https://doaj.org/article/3c779ea8ee734df687790b4c420295f7
Autor:
Ghazaleh Tavallaee, Starlee Lively, Jason S. Rockel, Shabana Amanda Ali, Michelle Im, Clementine Sarda, Greniqueca M. Mitchell, Evgeny Rossomacha, Sayaka Nakamura, Pratibha Potla, Sarah Gabrial, John Matelski, Anusha Ratneswaran, Kim Perry, Boris Hinz, Rajiv Gandhi, Igor Jurisica, Mohit Kapoor
Publikováno v:
Arthritis & Rheumatology. 74:1928-1942
Synovial fibrosis contributes to osteoarthritis (OA) pathology, but the underlying mechanisms remain unknown. We have observed increased microRNA-27b-3p (miR-27b-3p) levels in synovial fluid of patients with late-stage radiographic knee OA. Here, we