Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Prathab Balaji Saravanan"'
Autor:
Kenjiro Kumano, Mazhar A. Kanak, Prathab Balaji Saravanan, J. P. Blanck, Yang Liu, Srividya Vasu, Michael Lawrence, Bashoo Naziruddin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The immunosuppressive regimen for clinical allogeneic islet transplantation uses beta cell–toxic compounds such as tacrolimus that cause islet graft loss. Previously we reported that the plant-derived steroidal lactone Withaferin A (WA) ca
Externí odkaz:
https://doaj.org/article/baf64a9defc04421a7f7aa26bc8ec927
Autor:
Yoshitaro Shindo, Jagan Kalivarathan, Prathab Balaji Saravanan, Marlon F. Levy, Mazhar A. Kanak
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Islet culture before clinical transplantation has been adopted by various centers, but its effect on the survival and function of islets relative to the culture conditions and media needs further assessment. Human islets were cultured or preserved un
Externí odkaz:
https://doaj.org/article/544185ce136144e287a426a29aceed2a
Autor:
Prathab Balaji Saravanan, Jagan Kalivarathan, Faizaan Khan, Rashi Shah, Marlon F. Levy, Mazhar A. Kanak
Publikováno v:
Life Sciences. 324:121722
Publikováno v:
Diabetes. 71
Purpose: Islets undergo enormous stress during isolation and peri-transplant periods which causes a significant release of stressomes (exosomes released during stress) . Uncovering the biological role of such vesicles is vital for long-term graft fun
Autor:
Srividya Vasu, J. P. Blanck, Bashoo Naziruddin, Yang Liu, Michael C. Lawrence, Mazhar A. Kanak, Prathab Balaji Saravanan, Kenjiro Kumano
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
The immunosuppressive regimen for clinical allogeneic islet transplantation uses beta cell–toxic compounds such as tacrolimus that cause islet graft loss. Previously we reported that the plant-derived steroidal lactone Withaferin A (WA) can protect
Publikováno v:
Diabetes. 69
Differentiation of insulin-producing cells (IPCs) from stem cells has been widely studied as an alternative source for cell transplantation therapy in diabetes. Mesenchymal stem cells (MSCs) are a useful therapeutic option for islet transplants due t
Publikováno v:
Diabetes. 69
People with severe type 1 diabetes (T1D) are known to experience life-threatening hypoglycemic events as a result of alpha cell dysfunction. The phenomenon that causes α cell dysfunction is still unclear. It has been reported that β-cells regulate
Autor:
Carly M. Darden, Bashoo Naziruddin, Prathab Balaji Saravanan, Mazhar A. Kanak, Michael C. Lawrence, Charles A. Chang, Gumpei Yoshimatsu
Publikováno v:
American Journal of Transplantation. 18:982-989
High-quality pancreatic islets are essential for better posttransplantation endocrine function in total pancreatectomy with islet autotransplantation (TPIAT), yet stress during the isolation process affects quality and yield. We analyzed islet-enrich
Publikováno v:
Transplantation. 105:S40-S40
Publikováno v:
Transplantation. 105:S6-S6