Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Prateek gulhati"'
Autor:
Ritesh Kumar, Jongmyung Kim, Matthew P. Deek, Mariam F. Eskander, Prateek Gulhati, Haejin In, Timothy Kennedy, Mihir M. Shah, Miral S. Grandhi, Lyudmyla Berim, Kristen R. Spencer, Russell C. Langan, Howard S. Hochster, Patrick M. Boland, Salma K. Jabbour
Publikováno v:
Current Oncology, Vol 30, Iss 7, Pp 6432-6446 (2023)
Oncological outcomes are improving in gastrointestinal cancer with advancements in systemic therapies, and there is notable potential in combining immunotherapy and radiation therapy (RT) to allow for further improvements. Various preclinical and ear
Externí odkaz:
https://doaj.org/article/729b9f4c7e68413787e8c6f05e59d79e
Autor:
Ifeanyichukwu Ogobuiro, Yasmine Baca, Jennifer R Ribeiro, Phillip Walker, Gregory C Wilson, Prateek Gulhati, John L Marshall, Rachna T Shroff, David Spetzler, Matthew J Oberley, Daniel E Abbott, Hong Jin Kim, David A Kooby, Shishir K Maithel, Syed A Ahmad, Nipun B. Merchant, Joanne Xiu, Peter J. Hosein, Jashodeep Datta
Publikováno v:
medRxiv
PurposeUsing a real-world database with matched genomic-transcriptomic molecular data, we sought to characterize the distinct molecular correlates underlying clinical differences between young-onset pancreatic cancer (YOPC; MethodsWe analyzed matched
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c99b4a2810d8f89c23a8f69187a400
https://europepmc.org/articles/PMC10081424/
https://europepmc.org/articles/PMC10081424/
Autor:
Kristen Spencer, Howard S. Hochster, Anupama Chundury, H. Richard Alexander, Prateek Gulhati, L.D. Berim, David A. August, Timothy J. Kennedy, Swati Mamidanna, Salma K. Jabbour, Russell C. Langan, Matthew P. Deek, Mutlay Sayan, Patrick McKay Boland, Shane S. Neibart, Miral S. Grandhi
Publikováno v:
J Gastrointest Oncol
BACKGROUND: Neoadjuvant chemoradiotherapy can provide downstaging and improve margin negativity for borderline resectable and resectable pancreatic adenocarcinoma [(B)RPC]. Little is known about the relative efficacy of capecitabine (CAPE)-based vs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67419012b91af5ce7072913cb45669da
https://doi.org/10.21037/jgo-21-503
https://doi.org/10.21037/jgo-21-503
Autor:
Jun Yin, Prateek Gulhati, Michael J. Overman, Hans-Joachim Schmoll, Qian Shi, Christophe Tournigand, Aimery de Gramont, Levi Pederson, Paulo M. Hoff, Niall Tebbut, J. Randolph Hecht, Benoist Chibaudel, Jean-Yves Douillard
Publikováno v:
J Natl Cancer Inst
Background Carcinoembryonic antigen (CEA) levels are used in conjunction with imaging to monitor response to systemic therapy in metastatic colorectal cancer (mCRC). We sought to identify a threshold for CEA change from baseline to predict progressiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c67b07ccf2a79bc9ec09399589d58d
https://europepmc.org/articles/PMC7669230/
https://europepmc.org/articles/PMC7669230/
Autor:
Pingna Deng, Federica Carbone, Anders Ström, Y. Alan Wang, Wen Ting Liao, Prateek Gulhati, Huamin Wang, Parker Denz, Jun Li, Anirban Maitra, Tingxin Zhang, Er Yen Yen, Qing Chang, Denise J. Spring, Surendra Chaurasiya, Deepavali Chakravarti, Ronald A. DePinho, Nagireddy Putluri, Giannicola Genovese, Vincent Bernard, Haoqiang Ying, Bidyut Ghosh, Xiaoying Shang, Prasenjit Dey, Jianhua Zhang, Jielin Liu, Frederick Cavallaro
Publikováno v:
Cancer Discov
A hallmark of pancreatic ductal adenocarcinoma (PDAC) is an exuberant stroma comprised of diverse cell types that enable or suppress tumor progression. Here, we explored the role of oncogenic KRAS in protumorigenic signaling interactions between canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a1cd28fc69e877e6bd4202636e9e51
https://pubmed.ncbi.nlm.nih.gov/32046984
https://pubmed.ncbi.nlm.nih.gov/32046984
Publikováno v:
Cancer Letters. 319:1-7
The mammalian target of rapamycin (mTOR) plays a key role in regulation of cellular metabolism, growth, and proliferation. The frequent hyperactivation of mTOR signaling makes it an attractive target for therapeutic intervention and has driven the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3790642d1682a2fd562fc57c950377
https://doi.org/10.1016/j.canlet.2012.01.005
https://doi.org/10.1016/j.canlet.2012.01.005
Publikováno v:
Oncogene
PH domain leucine-rich-repeats protein phosphatase (PHLPP) is a family of Ser/Thr protein phosphatases that serve as tumor suppressors by negatively regulating Akt. Our recent studies have demonstrated that the ubiquitin proteasome pathway has an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3960fd9762370de026b6c18bc70b23
http://europepmc.org/articles/PMC3371166
http://europepmc.org/articles/PMC3371166
Autor:
Courtney M. Townsend, Xiaofu Wang, Prateek gulhati, Jing Li, B. Mark Evers, Heidi L. Weiss, Paul R. Dobner
Publikováno v:
Journal of Biological Chemistry. 286:542-554
Expression of the gene encoding neurotensin/neuromedin N (NT/N) is mostly limited to the brain and specialized enteroendocrine N cells in the distal small intestine. We have identified key regulatory elements in the promoter region that are involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9744eb9407a0a88e70b1130c6b503d1e
https://doi.org/10.1074/jbc.m110.145664
https://doi.org/10.1074/jbc.m110.145664
Autor:
B. Mark Evers, Hung Q. Doan, Dai H. Chung, Prateek gulhati, Junghee Kang, Piotr G. Rychahou, L. Andy Chen, Shu-Yuan Xiao
Publikováno v:
Proceedings of the National Academy of Sciences. 105:20315-20320
Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Understanding the distinct genetic and epigenetic changes contributing to the establishment and growth of metastatic lesions is crucial for the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc283826c50e83fd1d6c3d0c82088b39
https://doi.org/10.1073/pnas.0810715105
https://doi.org/10.1073/pnas.0810715105
Publikováno v:
Journal of Surgical Research. 144:238-239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa5c405d3bc53cb236f0e66c4481bacf
https://doi.org/10.1016/j.jss.2007.12.160
https://doi.org/10.1016/j.jss.2007.12.160