Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Pratap Meera"'
Autor:
Ethan W. Rohrbach, James D. Asuncion, Pratap Meera, Mason Kralovec, Sonali A. Deshpande, Felix E. Schweizer, David E. Krantz
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Aminergic nuclei in mammals are generally composed of relatively small numbers of cells with broad projection patterns. Despite the gross similarity of many individual neurons, recent transcriptomic, anatomic and behavioral studies suggest previously
Externí odkaz:
https://doaj.org/article/1f3e70440ffb4612a63e155e7567ebd7
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Dementia and autoimmune diseases are prevalent conditions with limited treatment options. Taurine and homotaurine (HT) are naturally occurring sulfonate amino acids, with taurine being highly abundant in animal tissues, but declining with age in the
Externí odkaz:
https://doaj.org/article/bd9b4f178fa4409b835d7e183ca82dd8
Publikováno v:
Neurobiology of Disease, Vol 143, Iss , Pp 104977- (2020)
Environmental toxicants have the potential to contribute to the pathophysiology of multiple complex diseases, but the underlying mechanisms remain obscure. One such toxicant is the widely used fungicide ziram, a dithiocarbamate known to have neurotox
Externí odkaz:
https://doaj.org/article/c2f0de159a524f28af31390283bca5d3
Publikováno v:
eLife, Vol 6 (2017)
Metabotropic glutamate receptor 1 (mGluR1) function in Purkinje neurons (PNs) is essential for cerebellar development and for motor learning and altered mGluR1 signaling causes ataxia. Downstream of mGluR1, dysregulation of calcium homeostasis has be
Externí odkaz:
https://doaj.org/article/a182b3c838a7433ea168ea14aa58e75b
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72976 (2013)
GABAA receptors (GABARs) are the targets of a wide variety of modulatory drugs which enhance chloride flux through GABAR ion channels. Certain GABAR modulators appear to acutely enhance the function of δ subunit-containing GABAR subtypes responsible
Externí odkaz:
https://doaj.org/article/62cdeef79ba14331aebcafbeb9c9ecb6
Publikováno v:
Journal of Neurochemistry. 165:445-454
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b167caffc59256a0f4fa8b73f7f9805
https://doi.org/10.1111/jnc.15774
https://doi.org/10.1111/jnc.15774
Autor:
Ali Y. Benkherouf, Pratap Meera, Sanna L. Soini, Mikko Uusi-Oukari, Kaisa‐Riitta Taina, Xiang-Guo Li, Martin Wallner, Asko J. Aalto
Publikováno v:
Journal of Neurochemistry. 149(1):41-53
Muscimol, the major psychoactive ingredient in the mushroom Amanita muscaria, has been regarded as a universal non-selective GABA-site agonist. Deletion of the GABAA receptor (GABAA R) δ subunit in mice (δKO) leads to a drastic reduction in high-af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2713c3cbf5f7d21b6de7572a590496
http://juuli.fi/Record/0338142419
http://juuli.fi/Record/0338142419
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 143, Iss, Pp 104977-(2020)
Neurobiology of Disease, Vol 143, Iss, Pp 104977-(2020)
Environmental toxicants have the potential to contribute to the pathophysiology of multiple complex diseases, but the underlying mechanisms remain obscure. One such toxicant is the widely used fungicide ziram, a dithiocarbamate known to have neurotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ecfe47bab54384479229242c74abf1
https://escholarship.org/uc/item/98n181zq
https://escholarship.org/uc/item/98n181zq
Autor:
Gabe Quinones, Anthony E. Oro, Stefan M. Pulst, Jessica Magri, Alexander S. Brown, Thomas S. Otis, Pratap Meera
Publikováno v:
Cell Cycle
Spinocerebellar ataxias (SCA) are a genetically heterogeneous family of cerebellar neurodegenerative diseases characterized by abnormal firing of Purkinje neurons and degeneration. We recently demonstrated the slowed firing rates seen in several SCAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5eb8ca0e93dbdf9abdb92d9ef8f0a1
https://europepmc.org/articles/PMC6961678/
https://europepmc.org/articles/PMC6961678/
Autor:
Stefan M. Pulst, Daniel R. Scoles, Pratap Meera, Karla P. Figueroa, Sharan Paul, Thomas S. Otis, Lance Pflieger, Julio C. Facelli, Warunee Dansithong
Publikováno v:
Human Molecular Genetics. 26:3069-3080
Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant neurodegenerative disease caused by CAG repeat expansion in the ATXN2 gene. The repeat resides in an encoded region of the gene resulting in polyglutamine (polyQ) expansion which has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b026bb8a53a60810166a96726e369ca6
https://doi.org/10.1093/hmg/ddx191
https://doi.org/10.1093/hmg/ddx191