Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pratanphorn Chuanprasit"'
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 24692-24705 (2013)
The metabolism of amine-containing drugs by cytochrome P450 enzymes (P450s) is prone to form a nitrosoalkane metabolic intermediate (MI), which subsequently coordinates to the heme iron of a P450, to produce a metabolic-intermediate complex (MIC). Th
Externí odkaz:
https://doaj.org/article/1d66c293af8a47ca94c9e24ba1d94b7e
Publikováno v:
Angewandte Chemie. 128:12262-12266
An asymmetric reductive amination of ketones using both arylamines and benzhydrazide in the presence of nickel catalysts was developed. A one-pot synthesis of tetrahydroquinoxalines was also developed starting directly from α-ketoaldehydes and 1,2-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d13cb579837af1e539a639166c9955
https://doi.org/10.1002/ange.201606821
https://doi.org/10.1002/ange.201606821
Publikováno v:
ACS Catalysis. 5:2952-2960
Cytochrome P450 enzymes (P450s) are ubiquitously distributed heme enzymes that play catalytic roles in the essential oxidative biotransformation of a wide range of exogenous and endogenous organic compounds. Strong inhibition of P450s through mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c75a50e8e50ddcac14deb9f8958f32a
https://doi.org/10.1021/acscatal.5b00423
https://doi.org/10.1021/acscatal.5b00423
Publikováno v:
Angewandte Chemie. 127:5201-5205
We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support the catalysts. As in enzymatic catalysis, attractive weak inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a31a099067f4adcb317b1ef727badf
https://doi.org/10.1002/ange.201501018
https://doi.org/10.1002/ange.201501018
Autor:
Hajime Hirao, Pratanphorn Chuanprasit
Publikováno v:
Chemical Physics Letters. 621:188-192
A series of density functional theory and G4 calculations are performed to quantify the extent to which proton-coupled electron transfer (PCET) lowers the barrier for H-abstraction in the reaction between 1,1-dimethylhydrazine (UDMH) and the compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5afbfbe23e6b61f4eb57bb8dcf2b23de
https://doi.org/10.1016/j.cplett.2014.12.027
https://doi.org/10.1016/j.cplett.2014.12.027
Autor:
Keiji Morokuma, Hajime Hirao, Kai Xu, Adhitya Mangala Putra Moeljadi, Pratanphorn Chuanprasit
Computational studies of molecules always require consideration of two competing factors that determine the reliability and feasibility of the computation, i.e. accuracy and computational cost. Especially when studying large molecular systems such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a15a4cab57838e94cca1074de8cf752c
https://doi.org/10.1039/9781782626831-00245
https://doi.org/10.1039/9781782626831-00245
Publikováno v:
ChemInform. 46
We report the use of nickel catalysts for the catalytic transfer hydrogenation of hydrazones and other ketimines with formic acid. Strongly donating bisphosphines must be used to support the catalysts. As in enzymatic catalysis, attractive weak inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec470b1951585358613d96c5ef4b3814
https://doi.org/10.1002/chin.201534113
https://doi.org/10.1002/chin.201534113
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 24692-24705 (2013)
International Journal of Molecular Sciences; Volume 14; Issue 12; Pages: 24692-24705
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 12; Pages: 24692-24705
International Journal of Molecular Sciences
The metabolism of amine-containing drugs by cytochrome P450 enzymes (P450s) is prone to form a nitrosoalkane metabolic intermediate (MI), which subsequently coordinates to the heme iron of a P450, to produce a metabolic-intermediate complex (MIC). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f791f3931b216e7d96c1eac86edf62
https://hdl.handle.net/10356/97420
https://hdl.handle.net/10356/97420
A precise understanding of the mechanism-based inactivation of cytochrome P450 enzymes (P450s) at the quantum mechanical level should allow more reliable predictions of drug–drug interactions than those currently available. Hydrazines are among the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a674ee53a371ce588bb3581c008e9f70
http://hdl.handle.net/10220/19082
http://hdl.handle.net/10220/19082
Publikováno v:
Chemistry - A European Journal. 19:7253-7253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf2ff591c525d845611a601bad1c1d4
https://doi.org/10.1002/chem.201390081
https://doi.org/10.1002/chem.201390081