Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older.

Autor: Prassek VV; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany., Rothenberg-Thurley M; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany., Sauerland MC; Institute of Biostatistics and Clinical Research, University of Münster, Germany., Herold T; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Janke H; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany., Ksienzyk B; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany., Konstandin NP; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany., Goerlich D; Institute of Biostatistics and Clinical Research, University of Münster, Germany., Krug U; Hospital Leverkusen, Germany., Faldum A; Institute of Biostatistics and Clinical Research, University of Münster, Germany., Berdel WE; Institute of Biostatistics and Clinical Research, University of Münster, Germany., Wörmann B; Charité - University Hospital Berlin, Germany., Braess J; Department of Oncology and Hematology, Hospital Barmherzige Brüder, Regensburg, Germany., Schneider S; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany., Subklewe M; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany., Bohlander SK; Department of Molecular Medicine and Pathology, University of Auckland, New Zealand., Hiddemann W; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Spiekermann K; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Metzeler KH; Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Germany klaus.metzeler@med.uni-muenchen.de.; German Cancer Consortium (DKTK), Partner Site Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.

Publikováno v: Haematologica [Haematologica] 2018 Nov; Vol. 103 (11), pp. 1853-1861. Date of Electronic Publication: 2018 Jun 14.