Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Prasoona Karra"'
Autor:
Maci Winn, Prasoona Karra, Benjamin Haaland, Jennifer A. Doherty, Scott A. Summers, Michelle L. Litchman, Marc J. Gunter, Mary C. Playdon, Sheetal Hardikar
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 606-618 (2023)
Abstract Background Metabolic syndrome (MetS), a group of risk factors that define metabolic dysfunction in adults, is strongly associated with obesity and is an emerging risk factor for cancer. However, the association of MetS and degree of metaboli
Externí odkaz:
https://doaj.org/article/b46a2bbe90c549d88a1c18a306295d51
Autor:
Maci Winn, Prasoona Karra, Heinz Freisling, Marc J. Gunter, Benjamin Haaland, Michelle L. Litchman, Jennifer A. Doherty, Mary C. Playdon, Sheetal Hardikar
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract Introduction Body mass index (BMI) fails to identify up to one‐third of normal weight individuals with metabolic dysfunction who may be at increased risk of obesity‐related cancer (ORC). Metabolic obesity phenotypes, an alternate metric
Externí odkaz:
https://doaj.org/article/ebf02c918437483aa5097ea33daa6d29
Autor:
Ze Zhang, John K. Wiencke, Karl T. Kelsey, Devin C. Koestler, Annette M. Molinaro, Steven C. Pike, Prasoona Karra, Brock C. Christensen, Lucas A. Salas
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionThe human brain comprises heterogeneous cell types whose composition can be altered with physiological and pathological conditions. New approaches to discern the diversity and distribution of brain cells associated with neurological condi
Externí odkaz:
https://doaj.org/article/10a18efbf4754420ba4472deb6d19ab0
Autor:
Mary C Playdon, Sheetal Hardikar, Prasoona Karra, Rachel Hoobler, Anna R Ibele, Katherine L Cook, Amanika Kumar, Joseph E Ippolito, Justin C Brown
Publikováno v:
JNCI Monographs. 2023:68-76
Obesity is a chronic, relapsing, progressive disease of excess adiposity that increases the risk of developing at least 13 types of cancer. This report provides a concise review of the current state of the science regarding metabolic and bariatric su
Autor:
Prasoona Karra, Maci Winn, Svenja Pauleck, Alicja Bulsiewicz‐Jacobsen, Lacie Peterson, Adriana Coletta, Jennifer Doherty, Cornelia M. Ulrich, Scott A. Summers, Marc Gunter, Sheetal Hardikar, Mary C. Playdon
Publikováno v:
Obesity (Silver Spring)
The metabolic dysfunction driven by obesity, including hyperglycemia and dyslipidemia, increases risk for developing at least 13 cancer types. The concept of "metabolic dysfunction" is often defined by meeting various combinations of criteria for met
Autor:
Prasoona Karra, Matthew J. Webber, William L. Holland, Danny Hung-Chieh Chou, Michael A. VandenBerg, Jin Hwan Kim, Nan Zheng
Publikováno v:
J Med Chem
Insulin has been a life-saving drug for millions of people with diabetes. However, several challenges exist which limit therapeutic benefits and reduce patient convenience. One key challenge is the fibrillation propensity, which necessitates refriger
Autor:
Prasoona Karra, Maci Winn, Benjamin Haaland, Garnet Anderson, Cynthia A. Thomson, Aladdin H. Shadyab, Juhua Luo, Nazmus Saquib, Howard Strickler, Rowan Chlebowski, Rhonda Arthur, Sheetal Hardikar, Mary C. Playdon
Publikováno v:
Cancer Research. 82:5880-5880
Introduction: Obesity-related cancer (ORC) diagnosed individuals are at an elevated risk of new-onset diabetes compared with cancer-free individuals. However, less is known about mortality among those with incident type 2 diabetes after cancer. Metho
Autor:
Yi Wolf Zhang, Prasoona Karra, William L. Holland, Alan Blakely, Christopher P. Hill, Danny Hung-Chieh Chou, Matthew J. Webber, Gabrielle Ghabash, Michael A. VandenBerg, Xiaochun Xiong, Frank G. Whitby
Publikováno v:
Chemical Science
A novel four-disulfide insulin analog was designed with retained bioactivity and increased fibrillation stability.
Although insulin was first purified and used therapeutically almost a century ago, there is still a need to improve therapeutic ef
Although insulin was first purified and used therapeutically almost a century ago, there is still a need to improve therapeutic ef