Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Prashila Amatya"'
Autor:
Maria A. Missinato, Sean Murphy, Michaela Lynott, Michael S. Yu, Anaïs Kervadec, Yu-Ling Chang, Suraj Kannan, Mafalda Loreti, Christopher Lee, Prashila Amatya, Hiroshi Tanaka, Chun-Teng Huang, Pier Lorenzo Puri, Chulan Kwon, Peter D. Adams, Li Qian, Alessandra Sacco, Peter Andersen, Alexandre R. Colas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Transdifferentiation has been proposed as an approach for regenerative medicine, but the mechanisms that safeguard cell identity are not well established. Here they identify transcription factors that oppose transdifferentiation and show that knockdo
Externí odkaz:
https://doaj.org/article/20fe073154364337abcffbba8fef58fe
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c7d165126df1b79c2e1ef05d27bca35
https://doi.org/10.7759/cureus.37906
https://doi.org/10.7759/cureus.37906
Autor:
Mark Mercola, Sanjay V. Malhotra, Ravindra Majeti, Matthew H. Porteus, Ronglih Liao, Volker Wiebking, Isabel Morgado, Yusuke Nakauchi, Saloni Gupta, Prashila Amatya, Michelle M. Vu, Dries A.M. Feyen, Ricardo Serrano, Wenqi Li, Arpit Dheeraj, Mallesh Pandrala, Dhanir Tailor, Arne A.N. Bruyneel, Anna P. Hnatiuk
Supplementary Table from Reengineering Ponatinib to Minimize Cardiovascular Toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c844dc6c35715db1639cea0b4e417f7
https://doi.org/10.1158/0008-5472.22431758
https://doi.org/10.1158/0008-5472.22431758
Autor:
Mark Mercola, Sanjay V. Malhotra, Ravindra Majeti, Matthew H. Porteus, Ronglih Liao, Volker Wiebking, Isabel Morgado, Yusuke Nakauchi, Saloni Gupta, Prashila Amatya, Michelle M. Vu, Dries A.M. Feyen, Ricardo Serrano, Wenqi Li, Arpit Dheeraj, Mallesh Pandrala, Dhanir Tailor, Arne A.N. Bruyneel, Anna P. Hnatiuk
Supplementary Figure from Reengineering Ponatinib to Minimize Cardiovascular Toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8813de7c26c00813e4b1aeccf4913459
https://doi.org/10.1158/0008-5472.22431764.v1
https://doi.org/10.1158/0008-5472.22431764.v1
Autor:
Mark Mercola, Sanjay V. Malhotra, Ravindra Majeti, Matthew H. Porteus, Ronglih Liao, Volker Wiebking, Isabel Morgado, Yusuke Nakauchi, Saloni Gupta, Prashila Amatya, Michelle M. Vu, Dries A.M. Feyen, Ricardo Serrano, Wenqi Li, Arpit Dheeraj, Mallesh Pandrala, Dhanir Tailor, Arne A.N. Bruyneel, Anna P. Hnatiuk
Small molecule tyrosine kinase inhibitors (TKI) have revolutionized cancer treatment and greatly improved patient survival. However, life-threatening cardiotoxicity of many TKIs has become a major concern. Ponatinib (ICLUSIG) was developed as an inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d40ba8736ba377c4c66ede63656f56e
https://doi.org/10.1158/0008-5472.c.6513977.v1
https://doi.org/10.1158/0008-5472.c.6513977.v1
Autor:
Anna P. Hnatiuk, Arne A.N. Bruyneel, Dhanir Tailor, Mallesh Pandrala, Arpit Dheeraj, Wenqi Li, Ricardo Serrano, Dries A.M. Feyen, Michelle M. Vu, Prashila Amatya, Saloni Gupta, Yusuke Nakauchi, Isabel Morgado, Volker Wiebking, Ronglih Liao, Matthew H. Porteus, Ravindra Majeti, Sanjay V. Malhotra, Mark Mercola
Publikováno v:
Cancer Research. 82:2777-2791
Small molecule tyrosine kinase inhibitors (TKI) have revolutionized cancer treatment and greatly improved patient survival. However, life-threatening cardiotoxicity of many TKIs has become a major concern. Ponatinib (ICLUSIG) was developed as an inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df831a95b4efdb29819b42ec16bf55f
https://doi.org/10.1158/0008-5472.can-21-3652
https://doi.org/10.1158/0008-5472.can-21-3652
Autor:
Chris Mehdizadeh, Prashila Amatya, Rod Partow-Navid, Ravi M. Rao, Daniel Rothstein, Mir Wasif Ali, Ramdas G. Pai
A 69-year-old female presented to the emergency department with chest pain and EKG changes consistent with anterior STEMI. Left heart catheterization revealed multi-vessel CAD. She was referred for a CABG. Transthoracic echocardiography (TTE) with co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1c3537a41c28625d17a2d88ef6aea5
https://doi.org/10.22541/au.167482488.80311461/v2
https://doi.org/10.22541/au.167482488.80311461/v2
Autor:
Anna Hnatiuk Hnatiuk, Arne Bruyneel, Dhanir Taylor, Mallesh Pandrala, Ricardo Serrano, Dries Feyen, Yusuke Nakauchi, Michelle Vu, Prashila Amatya, Ravindra Majeti, Sanjay Malhotra, Mark Mercola
Publikováno v:
Circulation Research. 131
Introduction: Ponatinib is one of the most cardiotoxic Tyrosine Kinase Inhibitors (TKIs), but continues to be used in clinical practice as it is the only TKI effective against the most common ABL T315I mutation in Chronic Myeloid Leukemia (CML). Long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2341257a29675072fdc9a5b586a5d790
https://doi.org/10.1161/res.131.suppl_1.p3105
https://doi.org/10.1161/res.131.suppl_1.p3105
Autor:
Ricardo Serrano, Dries Feyen, Arne A Bruyneel, Anna Hnatiuk Hnatiuk, Michelle Vu, Prashila Amatya, Isaac Perea Gil, Maricela Prado, Timon Seeger, Joseph C Wu, Ioannis Karakikes, Mark Mercola
Publikováno v:
Circulation Research. 131
Introduction: Drug-induced arrhythmias are a common cause for drug attrition during development and for restricted use or withdrawal from the market. Cell based assays to assess arrhythmia risk typically rely on the quantification of waveform feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::015a8fa1dd0afdc166db5f23e6118990
https://doi.org/10.1161/res.131.suppl_1.p2109
https://doi.org/10.1161/res.131.suppl_1.p2109
Autor:
Peter Andersen, Li Qian, Maria A. Missinato, Sean Murphy, Prashila Amatya, Christopher Lee, Alessandra Sacco, Michaela Lynott, Suraj Kannan, Alexandre R. Colas, Peter D. Adams, Pier Lorenzo Puri, Chun-Teng Huang, Anaïs Kervadec, Chulan Kwon, Hiroshi Tanaka, Michael S. Yu, Yu-Ling Chang, Mafalda Loreti
The comprehensive characterization of mechanisms safeguarding cell fate identity in differentiated cells is crucial for 1) our understanding of how differentiation is maintained in healthy tissues or misregulated in disease states and 2) to improve o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0953cb35f0c4219e6b07b959021186bb
https://doi.org/10.1101/2021.06.28.450261
https://doi.org/10.1101/2021.06.28.450261