Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Prashanth Ashok Kumar"'
Autor:
Elio Haroun, Prashanth Ashok Kumar, Ludovic Saba, Joseph Kassab, Krishna Ghimire, Dibyendu Dutta, Seah H. Lim
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract The intestinal barrier is a complex structure that not only regulates the influx of luminal contents into the systemic circulation but is also involved in immune, microbial, and metabolic homeostasis. Evidence implicating disruption in intes
Externí odkaz:
https://doaj.org/article/81e4bea9821445ef9c6a82759fa14439
Autor:
Prashanth Ashok Kumar, Stephen L. Graziano, Natalie Danziger, Dean Pavlick, Eric A. Severson, Shakti H. Ramkissoon, Richard S. P. Huang, Brennan Decker, Jeffrey S. Ross
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1157-1166 (2023)
Abstract Introduction New treatment strategies for advanced non‐small‐cell lung carcinoma (NSCLC) include synthetic lethality targets focused on protein arginine methyl transferases such as PRMT5 that exploit the impact of genomic loss of methylt
Externí odkaz:
https://doaj.org/article/f15a3e2f2d5648f0a02913152d789e83
Autor:
Prashanth Ashok Kumar, Serenella Serinelli, Daniel J. Zaccarini, Richard Huang, Natalie Danziger, Tyler Janovitz, Alina Basnet, Abirami Sivapiragasam, Stephen Graziano, Jeffrey S. Ross
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionKRAS mutation is a common occurrence in Pancreatic Ductal Adenocarcinoma (PDA) and is a driver mutation for disease development and progression. KRAS wild-type PDA may constitute a distinct molecular and clinical subtype. We used the Foun
Externí odkaz:
https://doaj.org/article/934a46cfb2774c2aa33aa3e9a1b28cd8
Autor:
Maroun Bou Zerdan, Prashanth Ashok Kumar, Dulce M. Barrios, Alanna Glidden, Dayana Nasr, Stephanie Niforatos, Ghanshyam Ghelani, Jennifer Leibovitch, Sandy Nasr, Binod KC, Mulham Ombada, Farzam Khokhar, Bhavya Poudyal, Jenish Bhandari, Myera Shahnawaz, Stephen Graziano, Seah H. Lim
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundMany co-existing medical conditions may affect the outcome in patients treated with immune checkpoint inhibitors for advanced cancer. There is currently not any information on whether metabolic syndrome (MetS) impacts the clinical outcome i
Externí odkaz:
https://doaj.org/article/553e90450542467bb054b954b836a303
Autor:
Michael Sandhu, Prashanth Ashok Kumar, Jared Deck, Maroun Bou Zerdan, Michael Lacombe, Abirami Sivapiragasam
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 11 (2023)
Radiation recall dermatitis is an inflammatory reaction of the skin that may infrequently occur in areas of the skin that have been previously treated with radiation therapy. This is thought to be due to a triggering agent administered after radiatio
Externí odkaz:
https://doaj.org/article/1bf1bcffd59342aca09332c4ded27cb6
Autor:
Prashanth Ashok Kumar MBBS, Mulham Ombada MBBS, Gayatri Pemmasani MBBS, Ajay Tambe MBBS, Katalin Banki MD, Teresa Gentile MD, PhD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 10 (2022)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare aggressive malignancy with poor outcomes. Although novel options like tagraxofusp, a CD123-directed cytotoxin, has emerged and is promising, treatment options are very limited in the rela
Externí odkaz:
https://doaj.org/article/2b667d66cca547d99639e1ebad13b826
Autor:
Samender Randhawa MD, Jessica Pinsker BS, Madhurya Amirapu MBBS, Metlapalli Venkata Sravanthi MBBS, Prashanth Ashok Kumar MBBS, Komal Akhtar MD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 10 (2022)
Perivascular epithelioid cell tumors (PEComas) are related to the tuberous sclerosis complex (TSC) and are commonly benign. When malignant, they can be aggressive with local invasion and metastatic spread. Conventional PEComas do not have TFE3 gene r
Externí odkaz:
https://doaj.org/article/a27782050b754006aac6431ad132c846
Autor:
Maroun Bou Zerdan, Prashanth Ashok Kumar, Daniel Zaccarini, Jeffrey Ross, Richard Huang, Abirami Sivapiragasam
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 519 (2023)
Introduction: Salivary gland carcinomas (SGC) are histologically diverse cancers and next-generation sequencing (NGS) to identify key molecular targets is an important aspect in the management of advanced cases. Methods: DNA was extracted from paraff
Externí odkaz:
https://doaj.org/article/932efb5fb3184e08a61d120d47d24558
Autor:
Komal Akhtar MD, Vrinda Vyas MBBS, Prashanth Ashok Kumar MBBS, James Corines DO, Gustavo de la Roza MD, Alina Basnet MD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 9 (2021)
Neuroendocrine tumors (NETs) are a heterogeneous group of tumors developing from neural crest cells, with numerous sites of origin, commonly the gastrointestinal and genitourinary tracts. NETs of the genitourinary tract are more common in women. Smal
Externí odkaz:
https://doaj.org/article/0e7d006dcc134339946785c308d3ed02
Autor:
Prashanth Ashok Kumar, Shweta Paulraj, Kanish Mirchia, Seung Shin Hahn, Abirami Sivapiragasam
Publikováno v:
Case Reports in Oncological Medicine, Vol 2020 (2020)
Carcinoma ex pleomorphic adenoma (Ca ex PA) is a rare malignant transformation of a benign primary pleomorphic adenoma (PA). We report the case of a 62-year-old male who presented with a swelling over his left temple. Imaging revealed a lytic lesion
Externí odkaz:
https://doaj.org/article/b2cb7f875f3446168df18d28966befba