Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Prashanth Anamthathmakula"'
Autor:
Prashanth Anamthathmakula, Philemon D. Shallie, Neha Nayak, Sabita Dhal, Jay L. Vivian, Gil Mor, Michael J. Soares, Nihar R. Nayak
Publikováno v:
Cells, Vol 12, Iss 16, p 2096 (2023)
The aromatase-Cre recombinase (Cyp19-Cre) transgenic mouse model has been extensively used for placenta-specific gene inactivation. In a pilot study, we observed unexpected phenotypes using this mouse strain, which prompted an extensive characterizat
Externí odkaz:
https://doaj.org/article/23884fd26a6147faa481f3144cb710c8
Autor:
Prashanth Anamthathmakula, Chandrashekara Kyathanahalli, Judith Ingles, Sonia S. Hassan, Jennifer C. Condon, Pancharatnam Jeyasuria
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 520-530 (2019)
Background: Circulating estrogen (E2) levels are high throughout pregnancy and increase towards term, however its local tissue specific actions vary across gestation. For example, myometrial E2 regulated uterotonic action is disabled until term, wher
Externí odkaz:
https://doaj.org/article/d736c0cbb97740cbb557d981030e478f
Autor:
William H Walker, Evan Easton, Rebecca S Moreci, Corey Toocheck, Prashanth Anamthathmakula, Pancharatnam Jeyasuria
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120783 (2015)
Androgens signal through the androgen receptor (AR) to regulate male secondary sexual characteristics, reproductive tract development, prostate function, sperm production, bone and muscle mass as well as body hair growth among other functions. We dev
Externí odkaz:
https://doaj.org/article/5a535a55ce7b48fdac76d2c63dfd0d53
Autor:
Giridharan Nappan V, Reddy Sirisha J, Kumar Chodavarapu, Prashanth Anamthathmakula, Prasad Sakamuri, Vajreswari Ayyalasomayajula
Publikováno v:
Lipids in Health and Disease, Vol 9, Iss 1, p 132 (2010)
Abstract 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and plays an important role in the development of obesity and metabolic syndrome. 11β-HSD1 activity is lower
Externí odkaz:
https://doaj.org/article/b6bc114fb42b4b19947016a966c1fbe1
Publikováno v:
Biology of Reproduction
Semen liquefaction is a proteolytic process where a gel-like ejaculated semen becomes watery due to the enzymatic activity of prostate-derived serine proteases in the female reproductive tract. The liquefaction process is crucial for the sperm to gai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a5593376111a4c5ef6d0e900c89101
http://europepmc.org/articles/PMC7523691
http://europepmc.org/articles/PMC7523691
Autor:
Prashanth Anamthathmakula, Emily A Harris, Gerardo G. Herrera, Ken-Ichi Takemaru, Jenna K Rock, Anna M Willie, Brooke E Barton, Wipawee Winuthayanon
Publikováno v:
Reproduction. 159:R125-R137
The oviduct (known as the fallopian tube in humans) is the site for fertilization and pre-implantation embryo development. Female steroid hormones, estrogen and progesterone, are known to modulate the morphology and function of cells in the oviduct.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dae5634f63417ac2ec317e7cc25f929b
https://doi.org/10.1530/rep-19-0189
https://doi.org/10.1530/rep-19-0189
Autor:
Pancharatnam Jeyasuria, Jennifer C. Condon, Prashanth Anamthathmakula, Chandrashekara Kyathanahalli
Publikováno v:
Current Opinion in Physiology. 13:135-140
Estrogen and estrogen action in the myometrium are necessary for a successful pregnancy. Estrogen is required for both the myometrial hyperplastic phase of gestation as well as the contractile response that leads to parturition at term. The excessive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e0d76e62a8bee3204a619d61f5a3bf
https://doi.org/10.1016/j.cophys.2019.10.017
https://doi.org/10.1016/j.cophys.2019.10.017
Publikováno v:
Biol Reprod
Prostate-specific antigen (PSA) is a prostate-specific serine protease enzyme that hydrolyzes gel-forming proteins (semenogelins) and changes the semen from gel-like to watery viscosity, a process called semen liquefaction. Highly viscous semen and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2facd7594c398074ddf607d7a18dec7f
https://pubmed.ncbi.nlm.nih.gov/35098308
https://pubmed.ncbi.nlm.nih.gov/35098308
Publikováno v:
Endocrinology
The mammalian oviduct is a dynamic organ where important events such as final maturation of oocytes, transport of gametes, sperm capacitation, fertilization, embryo development, and transport take place. Prostaglandin-endoperoxide synthase 2 (PTGS2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f11e2866930843eb7ce6314ffd403e8
https://doi.org/10.1210/endocr/bqab025
https://doi.org/10.1210/endocr/bqab025
Autor:
Wipawee Winuthayanon, Gerardo G. Herrera, Ryan M Finnerty, Brooke E Barton, Jenna K Rock, Prashanth Anamthathmakula, Anna M Willie, Emily A Harris
Publikováno v:
Biology of Reproduction
Inhibition of the sperm transport process in the female reproductive tract could lead to infertility. We previously showed that a pan-serine protease inhibitor, 4-(2-aminoethyl)benzenesulfonyl fluoride (AEBSF), blocked semen liquefaction in vivo and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e840b52a9a637bea58237d19cc654b81
https://pubmed.ncbi.nlm.nih.gov/32303757
https://pubmed.ncbi.nlm.nih.gov/32303757