Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Prashanth, Krishna Shastrula"'
Autor:
Cory Rice, Prashanth Krishna Shastrula, Andrew V. Kossenkov, Robert Hills, Duncan M. Baird, Louise C. Showe, Tzanko Doukov, Susan Janicki, Emmanuel Skordalakes
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
POT1 and TTP1 are part of the shelterin complex that caps and stabilizes the ends of telomeres. Here the authors present a structural analysis of the human POT1-TTP1 complex, shedding light on how it assembles and how cancer-associated mutations impa
Externí odkaz:
https://doaj.org/article/68a7e5604c6d4e68a53198a88c48aee9
Autor:
Ranotkar, Swapnil, Kumar, Parveen, Zutshi, Shubhranshu, Prashanth, Krishna Shastrula, Bezbaruah, Babul, Anand, Jay, Lahkar, Mangala
Publikováno v:
In Journal of Global Antimicrobial Resistance December 2014 2(4):205-212
Autor:
Yamsani, Abhinay, Prashanth, Krishna Shastrula, Kasala, Eshvendar Reddy, Kataki, Rubi, Bezbaruah, Babul Kumar
Publikováno v:
In Apollo Medicine March 2014 11(1):11-17
Autor:
Kumar, Parveen, Prashanth, Krishna Shastrula, Gaikwad, Anil Bhanudas, Vij, Mohit, Barua, Chandana C., Bezbaruah, Babul
Publikováno v:
In Environmental Toxicology and Pharmacology November 2013 36(3):883-890
Autor:
Alessandra Martorella, Prashanth Krishna Shastrula, David W. Speicher, Hsin Yao Tang, Dylan Fingerman, Valentina Vaira, Young Chan Chae, Dario C. Altieri, Dmitry I. Gabrilovich, Lucia R. Languino, Andrew V. Kossenkov, Gabriella Gaudioso, Vito W. Rebecca, Yu Geon Lee, Emmanuel Skordalakes, Ekta Agarwal, Jae Ho Seo, Stefano Ferrero, Manuela Caroli, Massimo Giroda, Davide Tosi, Meenhard Herlyn, Min Xiao, Alessandra Maria Storaci
Publikováno v:
Cancer research. 79(24)
The regulators of mitochondrial cell death in cancer have remained elusive, hampering the development of new therapies. Here, we showed that protein isoforms of mitochondrial fission factor (MFF1 and MFF2), a molecule that controls mitochondrial size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e70a7db018a90547814046f914df2d8
https://pubmed.ncbi.nlm.nih.gov/31836600
https://pubmed.ncbi.nlm.nih.gov/31836600
Autor:
Alyshia Newhart, Susan M. Janicki, James Hayden, Lucy M. Joo, Sara Lawrence Powers, Prashanth Krishna Shastrula, Isabel Sierra, Andrew R. Cohen
Publikováno v:
Molecular Biology of the Cell
RNase P protein subunits Rpp29, POP1, and Rpp21 interact with histone H3.3 upstream of nucleosome deposition, suggesting that a variant of this enzyme regulates H3.3 function. Rpp29 knockdown increases H3.3 chromatin incorporation, suggesting that it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e842c4c8237f91e44e92ffe17a5a9c40
https://doi.org/10.1091/mbc.e15-02-0099
https://doi.org/10.1091/mbc.e15-02-0099
Publikováno v:
The Journal of biological chemistry. 293(32)
The histone H3 variant H3.3 is a highly conserved and dynamic regulator of chromatin organization. Therefore, fully elucidating its nucleosome incorporation mechanisms is essential to understanding its functions in epigenetic inheritance. We previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3cd45f65c305863dce4b284f23882c
https://pubmed.ncbi.nlm.nih.gov/29921582
https://pubmed.ncbi.nlm.nih.gov/29921582
Publikováno v:
Nucleic Acids Research
The human CST (Ctc1, Stn1 and Ten1) complex binds the telomeric overhang and regulates telomere length by promoting C-strand replication and inhibiting telomerase-dependent G-strand synthesis. Structural and biochemical studies on the human Stn1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2c363c69720c05d36e879ec1fc9695
https://pubmed.ncbi.nlm.nih.gov/29228254
https://pubmed.ncbi.nlm.nih.gov/29228254
Autor:
Emmanuel Skordalakes, Prashanth Krishna Shastrula, Tzanko Doukov, Robert Kerrin Hills, Andrew V. Kossenkov, Louise C. Showe, Cory Rice, Susan M. Janicki, Duncan M. Baird
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
POT1 and TPP1 are part of the shelterin complex and are essential for telomere length regulation and maintenance. Naturally occurring mutations of the telomeric POT1–TPP1 complex are implicated in familial glioma, melanoma and chronic lymphocytic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc29f3054835b71ec887ccd1fe5b421
http://ora.ox.ac.uk/objects/uuid:
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