Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Prashant V. Bommi"'
Autor:
Ratnakar Tiwari, Prashant V. Bommi, Peng Gao, Matthew J. Schipma, Yalu Zhou, Susan E. Quaggin, Navdeep S. Chandel, Pinelopi P. Kapitsinou
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105086- (2022)
Summary: Endothelial cell (EC) metabolism has emerged as a driver of angiogenesis. While hypoxia inactivates the oxygen sensors prolyl-4 hydroxylase domain-containing proteins 1–3 (PHD1-3) and stimulates angiogenesis, the effects of PHDs on EC func
Externí odkaz:
https://doaj.org/article/de58eec9cc7d4fecaf154367ddc9764b
Autor:
Eduardo Vilar, Krishna M. Sinha, Paul A. Scheet, Laura Reyes-Uribe, Patrick M. Lynch, Selvi Thirumurthi, Melissa W. Taggart, Prashant V. Bommi, Kyle Chang, Zuhal Ozcan, Wenhui Wu, Ester Borras, Lewins Walter, Charles M. Bowen
Supplementary Figures S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b523383ea6ed7c41c8cbc715c1d8e63b
https://doi.org/10.1158/1940-6207.22533203.v1
https://doi.org/10.1158/1940-6207.22533203.v1
Autor:
Eduardo Vilar, Krishna M. Sinha, Paul A. Scheet, Laura Reyes-Uribe, Patrick M. Lynch, Selvi Thirumurthi, Melissa W. Taggart, Prashant V. Bommi, Kyle Chang, Zuhal Ozcan, Wenhui Wu, Ester Borras, Lewins Walter, Charles M. Bowen
Familial adenomatous polyposis (FAP) is a hereditary colorectal cancer syndrome, which results in the development of hundreds of adenomatous polyps carpeting the gastrointestinal tract. NSAIDs have reduced polyp burden in patients with FAP and synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496f2433906fe84eaafd676927af9daf
https://doi.org/10.1158/1940-6207.c.6546983.v1
https://doi.org/10.1158/1940-6207.c.6546983.v1
Autor:
Eduardo Vilar, Krishna M. Sinha, Paul A. Scheet, Laura Reyes-Uribe, Patrick M. Lynch, Selvi Thirumurthi, Melissa W. Taggart, Prashant V. Bommi, Kyle Chang, Zuhal Ozcan, Wenhui Wu, Ester Borras, Lewins Walter, Charles M. Bowen
Supplementary Tables S1-S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f6e585d83f3ca7f53b71c158baf048
https://doi.org/10.1158/1940-6207.22533200
https://doi.org/10.1158/1940-6207.22533200
Autor:
Eduardo Vilar, Samir M. Hanash, Krishna M. Sinha, Ignacio I. Wistuba, Paul A. Scheet, Winfried Edelmann, Patrick M. Lynch, Jared K. Burks, Melissa W. Taggart, Hong Wu, Jason A. Willis, Elena Tosti, Zuhal Ozcan, Alejandro Francisco-Cruz, Edwin R. Parra, Pedro Rocha, Hiroyuki Katayama, Wenhui Wu, Laura Reyes-Uribe, Charles M. Bowen, Prashant V. Bommi
Supplementary Figures S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e07b0b9865e84f5a0871086ea1bd16
https://doi.org/10.1158/0008-5472.22427484
https://doi.org/10.1158/0008-5472.22427484
Autor:
Eduardo Vilar, Samir M. Hanash, Krishna M. Sinha, Ignacio I. Wistuba, Paul A. Scheet, Winfried Edelmann, Patrick M. Lynch, Jared K. Burks, Melissa W. Taggart, Hong Wu, Jason A. Willis, Elena Tosti, Zuhal Ozcan, Alejandro Francisco-Cruz, Edwin R. Parra, Pedro Rocha, Hiroyuki Katayama, Wenhui Wu, Laura Reyes-Uribe, Charles M. Bowen, Prashant V. Bommi
Supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01326f39d3a820f35bf75a41efb83562
https://doi.org/10.1158/0008-5472.22427481.v1
https://doi.org/10.1158/0008-5472.22427481.v1
Autor:
Eduardo Vilar, Samir M. Hanash, Krishna M. Sinha, Ignacio I. Wistuba, Paul A. Scheet, Winfried Edelmann, Patrick M. Lynch, Jared K. Burks, Melissa W. Taggart, Hong Wu, Jason A. Willis, Elena Tosti, Zuhal Ozcan, Alejandro Francisco-Cruz, Edwin R. Parra, Pedro Rocha, Hiroyuki Katayama, Wenhui Wu, Laura Reyes-Uribe, Charles M. Bowen, Prashant V. Bommi
Supplementary Tables S1-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d4fc530493a63f5f4a5588f233120f
https://doi.org/10.1158/0008-5472.22427478
https://doi.org/10.1158/0008-5472.22427478
Autor:
Eduardo Vilar, Samir M. Hanash, Krishna M. Sinha, Ignacio I. Wistuba, Paul A. Scheet, Winfried Edelmann, Patrick M. Lynch, Jared K. Burks, Melissa W. Taggart, Hong Wu, Jason A. Willis, Elena Tosti, Zuhal Ozcan, Alejandro Francisco-Cruz, Edwin R. Parra, Pedro Rocha, Hiroyuki Katayama, Wenhui Wu, Laura Reyes-Uribe, Charles M. Bowen, Prashant V. Bommi
Lynch syndrome is the most common cause of hereditary colorectal cancer and is secondary to germline alterations in one of four DNA mismatch repair (MMR) genes. Here we aimed to provide novel insights into the initiation of MMR-deficient (MMRd) color
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9365eb19c13ccdcb1106614f159df49
https://doi.org/10.1158/0008-5472.c.6512688.v1
https://doi.org/10.1158/0008-5472.c.6512688.v1
Autor:
Pradip Raychaudhuri, Srilata Bagchi, Richard Benya, Adam Blunier, Dragana Kopanja, Krushna C. Patra, Jing Li, Indira Elangovan, Shaumick Bhattacharjee, Uppoor G. Bhat, Prashant V. Bommi, Nilotpal Roy
PDF file - 13093K, Supplementary Fig.1: Loss of DDB2 expression in human colon cancer. Supplementary Fig.2: Low magnification IHC data showing reduced expression of DDB2 in high grade colon cancer samples. Supplementary Fig.3: Depletion of DDB2 incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ac3af39c05282e3f8d7f809536de0d
https://doi.org/10.1158/0008-5472.22395558
https://doi.org/10.1158/0008-5472.22395558
Autor:
Lakshmi R. Bollu, Prashant V. Bommi, Paige J. Monsen, Lijie Zhai, Kristen L. Lauing, April Bell, Miri Kim, Erik Ladomersky, Xinyu Yang, Leonidas C. Platanias, Daniela E. Matei, Marcelo G. Bonini, Hidayatullah G. Munshi, Rintaro Hashizume, Jennifer D. Wu, Bin Zhang, Charles David James, Peiwen Chen, Masha Kocherginsky, Craig Horbinski, Michael D. Cameron, Arabela A. Grigorescu, Bakhtiar Yamini, Rimas V. Lukas, Gary E. Schiltz, Derek A. Wainwright
Publikováno v:
Journal of medicinal chemistry. 65(23)
Indoleamine 2,3-dioxygenase 1 (IDO1) is a potent immunosuppressive enzyme that inhibits the antitumor immune response through both tryptophan metabolism and non-enzymatic functions. To date, most IDO1-targeted approaches have focused on inhibiting tr