Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Prashant Nigade"'
Autor:
Jerry Tsai, Sadakatali Gori, Jesse Alt, Sandhya Tiwari, Jitesh Iyer, Rashmi Talwar, Denish Hinsu, Kailash Ahirwar, Swayam Mohanty, Chintan Khunt, Brijesh Sutariya, Kaushal Jani, Venkatesha Venkatasubbaiah, Ashok Patel, Jasmin Meghapara, Kaushal Joshi, Rajanikanta Sahu, Vijay Rana, Prashant Nigade, Ravi S Talluri, Kadiyala V S N Murty, Kiritkumar Joshi, Vikram Ramanathan, Ang Li, Nasif Islam, Ivan Snajdr, Pavel Majer, Rana Rais, Barbara S Slusher, Luis A Garza
Publikováno v:
PNAS Nexus. 2
Alopecia areata is a chronic hair loss disorder that involves autoimmune disruption of hair follicles by CD8+ T cells. Most patients present with patchy hair loss on the scalp that improves spontaneously or with topical and intralesional steroids, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7af018ea9f6e118cdcae9e7b9f2a38
https://doi.org/10.1093/pnasnexus/pgac297
https://doi.org/10.1093/pnasnexus/pgac297
Autor:
Nilesh Raghunath, Khedkar, Nageswara Rao, Irlapatti, Disha, Dadke, Vijay, Kanoje, Zubair, Shaikh, Vijay, Karche, Vikas, Shinde, Gokul, Deshmukh, Amit, Patil, Santosh, Jachak, Samiron, Phukan, Praveenkumar Anidil, Kizhakinagath, Milind, Gholve, Trupti, Bhankhede, Jagadeesh, Daler, Harshal Narendra, Nemade, Sagar, Budhe, Himani, Pareek, Rajesh, Yeshodharan, Rajesh, Gupta, Anil, Kalia, Dilip, Pandey, Akshaya, Wagh, Swaroop, Kumar, Vinod, Patil, Dipak, Modi, Nidhi, Sharma, Prajakta, Ahirrao, Maneesh, Mehta, Hemant, Kumar, Prashant, Nigade, Kaustubh, Tamane, Sadanand, Mallurwar, Sandip, Kuldharan, Shashikant, Pawar, Gururaj, Vishwase, Sanjay, Bokan, Minakshi, Singh, Kumar, Naik, Sachin, Ingawale, Rajesh, Shankar, Prabakaran, Kamalakannan, Spinvin, Venugopal, Shaji K, George, Kamlesh J, Padiya, Kumar V S, Nemmani, Jaysagar, Gundu, Mandar, Bhonde, Lakshmi, Narasimham, Milind, Sindkhedkar, Chirag, Shah, Neelima, Sinha, Sharad, Sharma, Dhananjay, Bakhle, Rajender Kumar, Kamboj, Venkata P, Palle
Publikováno v:
Journal of medicinal chemistry. 64(23)
The role of calcium release-activated calcium (CRAC) channels is well characterized and is of particular importance in T-cell function. CRAC channels are involved in the pathogenesis of several autoimmune diseases, making it an attractive therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caffeb96f8b24d3487ac270d9338a645
https://pubmed.ncbi.nlm.nih.gov/34843241
https://pubmed.ncbi.nlm.nih.gov/34843241
Autor:
Vijay Kanoje, Dilip Pandey, Akshaya Wagh, Sukanya Patra, Ajit Kumar Marisetti, Madhusudhan Reddy, Charudatt Samant, Nilesh Mahajan, Milind Gholve, Sudeep Sabde, Sneha Trivedi, Trupti Bhankhede, Vinod Patil, Prashant Nigade, Dipak Modi, Maneesh Mehta, Prajakta Ahirrao, Swathi Tota, Bidyut Nanda, Shashikant Pawar, Anuradha Polawar, Kaustubh Tamane, Sandip Kuldharan, Gururaj Vishwase, Nirmal Jana, Sachin J. Mahangare, Prashant Vidhate, Dipak Lagad, Jayasagar Gundu, Samiron Phukan, Manojkumar Shukla, Lakshmi Narasimham, Kumar V.S. Nemmani, Mandar Bhonde, Sharad Sharma, Rajender K. Kamboj, Venkata P. Palle
Publikováno v:
European Journal of Pharmacology. 927:175054
PI3Kδ plays a critical role in adaptive immune cell activation and function. Suppression of PI3Kδ has been shown to counter excessive triggering of immune responses which has led to delineating the role of this isoform in the pathophysiology of aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa76af2abcce55ae46c64c0a261b565
https://doi.org/10.1016/j.ejphar.2022.175054
https://doi.org/10.1016/j.ejphar.2022.175054
Autor:
Manojkumar R, Shukla, Sukanya, Patra, Mahip, Verma, Gayathri, Sadasivam, Nirmal, Jana, Sachin J, Mahangare, Prashant, Vidhate, Dipak, Lagad, Anand, Tarage, Murthy, Cheemala, Chaitanya, Kulkarni, Shankar, Bhagwat, Vinod D, Chaudhari, Majid, Sayyed, Vipul, Pachpute, Ramesh, Phadtare, Gopal, Gole, Samiron, Phukan, Brahmam, Sunkara, Charudatt, Samant, Manisha, Shingare, Aditya, Naik, Sneha, Trivedi, Ajit Kumar, Marisetti, Madhusudhan, Reddy, Milind, Gholve, Nilesh, Mahajan, Sudeep, Sabde, Vinod, Patil, Dipak, Modi, Maneesh, Mehta, Prashant, Nigade, Kaustubh, Tamane, Swati, Tota, Hemant, Goyal, Harish, Volam, Shashikant, Pawar, Prajakta, Ahirrao, Lal, Dinchhana, Sadanand, Mallurwar, Atul, Akarte, Anand, Bokare, Rupesh, Kanhere, Neetinkumar, Reddy, Sarita, Koul, Manoj, Dandekar, Minakshi, Singh, Peter R, Bernstein, Lakshmi, Narasimham, Mandar, Bhonde, Jayasagar, Gundu, Rajan, Goel, Sanjeev, Kulkarni, Sharad, Sharma, Rajender Kumar, Kamboj, Venkata P, Palle
Publikováno v:
Journal of medicinal chemistry. 63(23)
PI3Kδ inhibitors have been approved for B-cell malignancies like CLL, small lymphocytic lymphoma, and so forth. However, currently available PI3Kδ inhibitors are nonoptimal, showing weakness against at least one of the several important properties:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9740bbdfcab4b764d76303bebfd167f6
https://pubmed.ncbi.nlm.nih.gov/33297683
https://pubmed.ncbi.nlm.nih.gov/33297683
Publikováno v:
European Journal of Drug Metabolism & Pharmacokinetics; Dec2018, Vol. 43 Issue 6, p615-617, 3p