Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Prashant Kashinath Bhavar"'
Publikováno v:
Cancer Research. 83:1076-1076
In the U.S., pancreatic cancer is 9th most commonly diagnosed cancer (depending on gender), but the fourth leading cause of cancer death in men and women. FOLFIRINOX or gemcitabine plus nab-paclitaxel have been the standard of care for pancreatic can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c5adc93ef3308e459acd28291c73bd
https://doi.org/10.1158/1538-7445.am2023-1076
https://doi.org/10.1158/1538-7445.am2023-1076
Publikováno v:
Cancer Research. 83:4481-4481
Pancreatic cancer is an intractable malignancy and is the seventh leading cause of global cancer deaths in industrialized countries and the third most common in the USA. Despite advancement in the knowledge of potential risk factors that cause pancre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc767770c09182748e44c03fc944c898
https://doi.org/10.1158/1538-7445.am2023-4481
https://doi.org/10.1158/1538-7445.am2023-4481
Autor:
Prashant Kashinath Bhavar, Uday Kumar Surampudi, Partha Pratim Sarma, Satish Katike, Adilakshmi Gandham
Publikováno v:
Cancer Research. 83:A037-A037
Prostate cancer is one of the most commonly diagnosed and fourth leading cause of cancer death in men, with low survival rates for metastatic cancers. Androgen receptor (AR) is one of the most altered Oncogenes in castration-resistant prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a778bd1da6ea2a68b7c604d198d464d6
https://doi.org/10.1158/1538-7445.metastasis22-a037
https://doi.org/10.1158/1538-7445.metastasis22-a037
Autor:
Prashant Kashinath Bhavar, Uday Kumar Surampudi, Partha Pratim Sarma, Mahesh Mohan Shidore, Anuj Ramesh Kshirsagar
Publikováno v:
Cancer Research. 82:2681-2681
RAS proteins are family of small GTP-binding proteins that play a major role in regulating cellular responses such as proliferation, differentiation, migration, and cell growth. RAS proteins function as molecular switches, cycling between inactive (G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a8d073ddad7325da25e583c5ed3119c
https://doi.org/10.1158/1538-7445.am2022-2681
https://doi.org/10.1158/1538-7445.am2022-2681
Autor:
Prashant Kashinath Bhavar, Uday Kumar Surampudi, Partha Pratim Sarma, Mahesh Mohan Shidore, Anuj Ramesh Kshirsagar
Publikováno v:
Cancer Research. 82:4107-4107
KRASG12C is an important oncogenic driver mutation and occurs in about 13% of NSCLC and 1-3% of colorectal and other solid tumors. Lumakras࣪ (sotorasib), a KRASG12C inhibitor was recently approved for treatment of NSCLC, and others, such as, Adagra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9ac855b7d6842ace1af069df31e791a
https://doi.org/10.1158/1538-7445.am2022-4107
https://doi.org/10.1158/1538-7445.am2022-4107
Autor:
Prashant Kashinath Bhavar, Sridhar Veeraraghavan, Srikant Viswanadha, Gayatriswaroop Merikapudi, Babu Govindrajulu, Swaroop Vakkalanka, Satyanarayana Eleswarapu
Publikováno v:
Molecular Cancer Therapeutics. 14:B171-B171
Background: Cancer cells preferentially channel glucose towards lactate production even when oxygen is plentiful, a process termed “aerobic glycolysis” or the Warburg effect. The entire metabolic machinery is reprogrammed in cancer cells wherein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b58de6dce0c62ff356f7bd3b67f6c577
https://doi.org/10.1158/1535-7163.targ-15-b171
https://doi.org/10.1158/1535-7163.targ-15-b171
Autor:
Nagarathnam Dhanapalan, Srikant Viswanadha, Sumalatha Kuppireddi, Meyyappan Muthuppalaniappan, Sridhar Veeraraghavan, Babu Govindarajulu, Swaroop Vakkalanka, Kanthikiran Varanasi, Prashant Kashinath Bhavar
Publikováno v:
Cancer Research. 72:1789-1789
Background: c-Met is a proto-oncogene that encodes the protein Met with intrinsic tyrosine kinase activity. Aberrant Met kinase activity triggers a series of unwarranted phosphorylation events and signalling processes that ultimately lead to the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f825114a5c061dd557744e317c029c62
https://doi.org/10.1158/1538-7445.am2012-1789
https://doi.org/10.1158/1538-7445.am2012-1789