Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Prashant J. Ruchaya"'
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Akademický článek
Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart
Autor: Panagiota Siatra, Giannis Vatsellas, Athanasia Chatzianastasiou, Evangelos Balafas, Theodora Manolakou, Andreas Papapetropoulos, Anna Agapaki, Eleni-Taxiarchia Mouchtouri, Prashant J. Ruchaya, Artemis G. Korovesi, Manolis Mavroidis, Dimitrios Thanos, Dimitris Beis, Ioannis Kokkinopoulos
Publikováno v: npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract The single curative measure for heart failure patients is a heart transplantation, which is limited due to a shortage of donors, the need for immunosuppression and economic costs. Therefore, there is an urgent unmet need for identifying cell
Externí odkaz: https://doaj.org/article/afb017e7160444369f58568890f423c0
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3
Importance of AT1 and AT2 receptors in the nucleus of the solitary tract in cardiovascular responses induced by a high-fat diet
Autor: Debora S. A. Colombari, Maria Andréia Delbin, Hongwei Li, Eduardo Colombari, Mariana Rosso Melo, José Vanderlei Menani, Guilherme Fleury Fina Speretta, Mirian Bassi, Colin Sumners, Prashant J. Ruchaya
Publikováno v: Hypertension Research
A high-fat diet (HFD) induces an increase in arterial pressure and a decrease in baroreflex function, which may be associated with increased expression of angiotensin type 1 receptor (AT1R) and pro-inflammatory cytokine genes and reduced expression o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695cb6ec8405eb232e661d819d1ad146
https://doi.org/10.1038/s41440-018-0196-0
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4
Increased Expression of Macrophage Migration Inhibitory Factor in the Nucleus of the Solitary Tract Attenuates Renovascular Hypertension in Rats
Autor: Hongwei Li, José Vanderlei Menani, Guilherme Fleury Fina Speretta, Daniel Penteado Martins Dias, Rafaela Moreira Barbosa, Debora S. A. Colombari, Colin Sumners, Prashant J. Ruchaya, Eduardo Colombari
Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2018-11-26T17:33:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-04-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) NIH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a15d1b37d37310b9776c29d3e524a9a
https://doi.org/10.1093/ajh/hpx001
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5
An injectable capillary-like microstructured alginate hydrogel improves left ventricular function after myocardial infarction in rats
Autor: Yanfei Qi, John W. Petersen, Andres Rubiano, Bradley J. Willenberg, Prateek S. Wate, Christopher R. Cogle, Leonardo F. Ferreira, Barry J. Byrne, Prashant J. Ruchaya, Tianyao Huo, Elizabeth Wise, Carl J. Pepine, Chelsey S. Simmons, Christopher D. Batich, Eileen M. Handberg, Domenico G. Della Rocca
Publikováno v: International Journal of Cardiology. 220:149-154
Background A new post-myocardial infarction (MI) therapy is injection of high-water-content polymeric biomaterial gels (hydrogels) into damaged myocardium to modulate cardiac negative remodeling and preserve heart function. Methods We investigated th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ac3643ef644af6d989516e346b0d34
https://doi.org/10.1016/j.ijcard.2016.06.158
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6
Aged-senescent cells contribute to impaired heart regeneration
Autor: Wael Awad, Prashant J Ruchaya, James Clark, Larissa G.P. Langhi Prata, Beverley J. Cottle, Eva Domenjo-Vila, Georgina M. Ellison-Hughes, Fiona C Lewis-McDougall, Tamara Tchkonia, Daniele Torella, Prakash P Punjabi, Tze Shin Teoh, James L. Kirkland
Publikováno v: Lewis-McDougall, F C, Ruchaya, P J, Domenjo-Vila, E, Teoh, T S, Prata, L, Cottle, B J, Clark, J E, Punjabi, P P, Awad, W, Torella, D, Tchkonia, T, Kirkland, J L & Ellison-Hughes, G M 2019, ' Aged-senescent cells contribute to impaired heart regeneration ', AGING CELL, vol. 18, no. 3, e12931 . https://doi.org/10.1111/acel.12931
Aging leads to increased cellular senescence and is associated with decreased potency of tissue-specific stem/progenitor cells. Here we have done an extensive analysis of cardiac progenitor cells (CPCs) isolated from human subjects with cardiovascula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50940695afc10fe182eca5843cda06bb
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7
Overexpression of AT2R in the solitary-vagal complex improves baroreflex in the spontaneously hypertensive rat
Autor: Prashant J. Ruchaya, José Vanderlei Menani, Guilherme Fleury Fina Speretta, Colin Sumners, Eduardo Colombari, Debora S. A. Colombari, Graziela Torres Blanch, Hongwei Li
Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2018-11-26T17:13:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7671b999c512bccaf87e4ad94606c83
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9
206 The transplantation of sca-1+/pw1+/pax7- skeletal muscle-derived interstitial progenitor cells (pics) improves cardiac function in mice subjected to myocardial infarction
Autor: Giulia Gritti, Georgina M. Ellison-Hughes, Prashant J Ruchaya, Sachin Amin
Publikováno v: Heart. 103:A138.1-A138
Introduction Stem cell-based regenerative therapies are fast becoming an attractive and highly promising treatment for heart disease and failure. Sca-1+/PW1+/Pax7-skeletal muscle-derived interstitial progenitor cells (PICs) regenerate adult skeletal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c06e34efa2e2c13c4642e556c2e6c83
https://doi.org/10.1136/heartjnl-2017-311726.204
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10
Akademický článek
Transplantation of Skeletal Muscle-Derived Sca-1+/PW1+/Pax7− Interstitial Cells (PICs) Improves Cardiac Function and Attenuates Remodeling in Mice Subjected to Myocardial Infarction
Autor: Prashant J Ruchaya, Fiona C. Lewis-McDougall, Nitiphat Sornkarn, Sachin Amin, Benjamin Grimsdell, Abeer Shaalan, Guilia Gritti, Kyi Thar Soe, James E. Clark, Georgina M. Ellison-Hughes
Publikováno v: Cells, Vol 11, Iss 24, p 4050 (2022)
We have previously shown that skeletal muscle-derived Sca-1+/PW1+/Pax7− interstitial cells (PICs) are multi-potent and enhance endogenous repair and regeneration. Here, we investigated the regenerative potential of PICs following intramyocardial tr
Externí odkaz: https://doaj.org/article/65802af6bc8d4326a602c5681ba33dba
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