Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Prashant, Desai"'
Autor:
Peter Naniima, Eleonora Naimo, Sandra Koch, Ute Curth, Khaled R. Alkharsah, Luisa J. Ströh, Anne Binz, Jan-Marc Beneke, Benjamin Vollmer, Heike Böning, Eva Maria Borst, Prashant Desai, Jens Bohne, Martin Messerle, Rudolf Bauerfeind, Pierre Legrand, Beate Sodeik, Thomas F. Schulz, Thomas Krey
Publikováno v:
PLoS Biology, Vol 19, Iss 11 (2021)
Herpesviruses cause severe diseases particularly in immunocompromised patients. Both genome packaging and release from the capsid require a unique portal channel occupying one of the 12 capsid vertices. Here, we report the 2.6 Å crystal structure of
Externí odkaz:
https://doaj.org/article/5baa5853f4194387a43957495e2d295d
Autor:
Jaeyeun Lee, Jennifer Stone, Prashant Desai, John G. Kosowicz, Jun O. Liu, Richard F. Ambinder
Publikováno v:
Viruses, Vol 13, Iss 5, p 812 (2021)
Following our observation that clofoctol led to Epstein–Barr virus (EBV) lytic gene expression upon activation of the integrated stress response (ISR), we decided to investigate the impact of As2O3 on viral lytic gene expression. As2O3 has also bee
Externí odkaz:
https://doaj.org/article/e56d079197c3438caf75c167e0321bbc
Autor:
Sydney Simpson, Guillaume Fiches, Maxime J. Jean, Michael Dieringer, James McGuinness, Sinu P. John, Meir Shamay, Prashant Desai, Jian Zhu, Netty G. Santoso
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic virus responsible for the development of Kaposi’s sarcoma, primary effusion lymphoma (PEL), and Multicentric Castleman’s disease in immunocompromised individuals. Despite the burden
Externí odkaz:
https://doaj.org/article/7233ed0a1945489f856f6b9c67d0a0b5
Publikováno v:
Phytotaxa. 521:212-218
The correct authority of Astragalus vogelii subsp. fatimensis and its distribution range in India are discussed. The taxon, which is considered rare in India, has been recollected from Gujarat State from new localities in the Banaskantha District. Th
Publikováno v:
AJOB Neuroscience. 13:68-70
Autor:
Prashant Desai, Rista Upadhyay, Chad Suissa, Barry J. Margulies, Gregory M. Lesko, Lauren A. Sadowski
Publikováno v:
Journal of Visualized Experiments.
There are numerous published protocols for plaquing viruses, including references within primary literature for methodology. However, plaquing viruses can be difficult to perform, requiring focus on its specifications and refinement. It is an incredi
Autor:
Prashant Desai, Eleonora Naimo, Ute Curth, Heike Böning, Benjamin Vollmer, Eva Maria Borst, Pierre Legrand, Martin Messerle, Peter Naniima, Thomas Krey, Jens Bohne, Rudolf Bauerfeind, Sandra Koch, Beate Sodeik, Anne Binz, Jan-Marc Beneke, Thomas F. Schulz, Luisa J Ströh, Khaled R. Alkharsah
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 11, p e3001423 (2021)
PLoS Biology, Vol 19, Iss 11 (2021)
PLoS Biology, Vol 19, Iss 11, p e3001423 (2021)
PLoS Biology, Vol 19, Iss 11 (2021)
Herpesviruses cause severe diseases particularly in immunocompromised patients. Both genome packaging and release from the capsid require a unique portal channel occupying one of the 12 capsid vertices. Here, we report the 2.6 Å crystal structure of
Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics
Autor:
Ronnie C. Mease, Michele Doucet, Sridhar Nimmagadda, Edward Gabrielson, Ala Lisok, Sagar Shelake, Sudipto Ganguly, Akhilesh Mishra, Elizabeth M. Jaffee, Rupashree Sen, Patrick M. Forde, Dhananjay Vaidya, Ravindra A. De Silva, Jamie B. Spangler, Donika Plyku, Dhiraj Kumar, Rakeeb Kureshi, Prashant Desai
Publikováno v:
Proc Natl Acad Sci U S A
Macromolecules such as monoclonal antibodies (mAbs) are likely to experience poor tumor penetration because of their large size, and thus low drug exposure of target cells within a tumor could contribute to suboptimal responses. Given the challenge o
Autor:
Prashant Desai, Robert M. Feinberg
Publikováno v:
Journal of International Trade Law and Policy. 19:1-7
Purpose The issue of substitutability between various modes of import protection has been studied by economists in various ways. Since President Donald Trump came into office and soon started imposing tariffs, the need by US firms to file antidumping
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104640 (2014)
Herpesvirus capsids are regular icosahedrons with a diameter of a 125 nm and are made up of 162 capsomeres arranged on a T = 16 lattice. The capsomeres (VP5) interact with the triplex structure, which is a unique structural feature of herpesvirus cap
Externí odkaz:
https://doaj.org/article/cb8d0749093f4dfb8cbcb41da16358b6