Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Prasanna Bhat"'
Autor:
Prasanna Bhat, Vasilisa Aksenova, Matthew Gazzara, Emily A. Rex, Sadaf Aslam, Christina Haddad, Shengyan Gao, Matthew Esparza, Tolga Cagatay, Kimberly Batten, Sara S. El Zahed, Alexei Arnaoutov, Hualin Zhong, Jerry W. Shay, Blanton S. Tolbert, Mary Dasso, Kristen W. Lynch, Adolfo García-Sastre, Beatriz M. A. Fontoura
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the nucleoporins localized at the nucleoplasmic side o
Externí odkaz:
https://doaj.org/article/ef526c85c77e4e78867cbdc75323343a
Autor:
Yihu Xie, Shengyan Gao, Ke Zhang, Prasanna Bhat, Bradley P. Clarke, Kimberly Batten, Menghan Mei, Matthew Gazzara, Jerry W. Shay, Kristen W. Lynch, Alexia E. Angelos, Pate S. Hill, Austin L. Ivey, Beatriz M.A. Fontoura, Yi Ren
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112988- (2023)
Summary: mRNA in eukaryotic cells is packaged into highly compacted ribonucleoprotein particles (mRNPs) in the nucleus and exported to the cytoplasm for translation. mRNP packaging and export require the evolutionarily conserved transcription-export
Externí odkaz:
https://doaj.org/article/df54e3fcb6014d21ab1a152352313d47
Autor:
Vasilisa Aksenova, Alexandra Smith, Hangnoh Lee, Prasanna Bhat, Caroline Esnault, Shane Chen, James Iben, Ross Kaufhold, Ka Chun Yau, Carlos Echeverria, Beatriz Fontoura, Alexei Arnaoutov, Mary Dasso
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
mRNAs export from the nucleus is thought to be regulated in part by three nucleoporins that comprise the nuclear basket, but whether and how distinct basket nucleoporins interact with the RNA export machinery is unclear. Here, the authors use rapid a
Externí odkaz:
https://doaj.org/article/b11e933a22b94f5d92aa8aec90845e1b
Autor:
Deepashree Rajshekar, Kavita V. Chaudhari, Prasanna Bhat, Suman S. Prakash, Ramya Raghvan, Shruthi Vasanth, Sunil Jayakar, Radha Sugumaran, Rachana Kannambath, Sushmita Chowdury, R. Sneha, Athira Nair, V. Greeshma, Dhanalakshmi Rajavelu, Apurba S. Sastry
Publikováno v:
Journal of Laboratory Physicians, Vol 11, Iss 02, Pp 154-160 (2019)
BACKGROUND: Rapid turnaround time of blood culture reports should be the main motive for a clinical microbiologist for optimal patient care. Categorical agreement (CA) between direct disk diffusion (dDD) and reference disk diffusion (rDD) may vary be
Externí odkaz:
https://doaj.org/article/3316f22347204ff1b2bf1e0382899e3c
Autor:
Matthew G Thompson, Mark Dittmar, Michael J Mallory, Prasanna Bhat, Max B Ferretti, Beatriz MA Fontoura, Sara Cherry, Kristen W Lynch
Publikováno v:
eLife, Vol 9 (2020)
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that infection of human lung epithelial cells with influenza A virus (IAV) also induces a broad program of alternative splicing of host
Externí odkaz:
https://doaj.org/article/a84b06f84ac540deb0cf5b99ca91f58a
Autor:
Matthew G. Thompson, Raquel Muñoz-Moreno, Prasanna Bhat, Renat Roytenberg, John Lindberg, Matthew R. Gazzara, Michael J. Mallory, Ke Zhang, Adolfo García-Sastre, Beatriz M. A. Fontoura, Kristen W. Lynch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Alternative splicing of influenza A virus (IAV) M transcript is regulated by hnRNP K and NS1-BP, but mechanistic details are unknown. Here, Thompson et al. show how hnRNP K and NS1-BP bind M mRNA and that these proteins regulate splicing of host tran
Externí odkaz:
https://doaj.org/article/c52fbc273a8e43cdb154def6db8f151a
Autor:
Jyoti Nain, R Deepashree, Pratibha Tamang, Prasanna Bhat, Suman Prakash, R Sneha, T Kalpana, G Anitha, Apurba Sankar Sastry
Publikováno v:
Journal of Current Research in Scientific Medicine, Vol 4, Iss 2, Pp 98-103 (2018)
Introduction: Gram staining of smears prepared from positively flagged blood culture bottles plays a vital role because its accurate interpretation helps the clinicians to modify empirical therapy as well as to perform the direct susceptibility test,
Externí odkaz:
https://doaj.org/article/c330af974cfd439985f23cbd98d8f10d
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 13, Iss 2, Pp DC01-DC06 (2019)
Introduction: Hepatitis B Virus (HBV) causes acute and chronic liver disease which can progress to cirrhosis and hepatocellular carcinoma. The seroprevalence in India is about 2% to 8%. When compared to general population, seroprevalence in HCWs is 2
Externí odkaz:
https://doaj.org/article/0677de2e3934479faef29e7c97bb00dd
Autor:
Jerry W. Shay, Jue Liang, Prasanna Bhat, Joseph M. Ready, Beatriz M. A. Fontoura, Matthew Esparza, Bruce A. Posner, Jacinth Naidoo, Busola R. Alabi, Kris M. White, Adolfo García-Sastre, Briana L. McGovern, Michael A. P. Williams, Hanspeter Niederstrasser
Publikováno v:
J Med Chem
Influenza viruses cause approximately half a million deaths every year worldwide. Vaccines are available but partially effective, and the number of antiviral medications is limited. Thus, it is crucial to develop therapeutic strategies to counteract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102ae0fa36cea01ac5679fd1604e2960
https://doi.org/10.1021/acs.jmedchem.1c00304
https://doi.org/10.1021/acs.jmedchem.1c00304
"A collection of cognitive, social, and interpersonal abilities that assist people to make informed decisions, solve problems, think critically, intellectually to develop good relationships, and manage their lives in a productive way," is how life sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db45565957d6295af5db4dae8b68d87
