Zobrazeno 1 - 10
of 425
pro vyhledávání: '"Prasad S. Adusumilli"'
Autor:
Bryan C. Husta, Anu Menon, Reza Bergemann, I-Hsin Lin, Jaclyn Schmitz, Rastko Rakočević, Tejaswi R. Nadig, Prasad S. Adusumilli, Jason A. Beattie, Robert P. Lee, Bernard J. Park, Gaetano Rocco, Matthew J. Bott, Mohit Chawla, Or Kalchiem-Dekel
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Introduction This study aims to answer the question of whether adding mobile cone-beam computed tomography (mCBCT) imaging to shape-sensing robotic-assisted bronchoscopy (ssRAB) translates into a quantifiable improvement in the tool–lesion relation
Externí odkaz:
https://doaj.org/article/d2006be4b6994af3b4e3ba298226727c
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 1, Pp 100618- (2024)
Introduction: Cohen’s kappa is often used to quantify the agreement between two pathologists. Nevertheless, a high prevalence of the feature of interest can lead to seemingly paradoxical results, such as low Cohen’s kappa values despite high “o
Externí odkaz:
https://doaj.org/article/3a401e2fce734f0eb5f26212206efd78
Autor:
Zachary E. Tano, Stefan Kiesgen, Navin K. Chintala, Jordan Dozier, Hue Tu Quach, John Messinger, Kay See Tan, Prasad S. Adusumilli
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 11, Pp 100622- (2023)
Summary: Current in vitro and in vivo assays used to study immunotherapeutic interventions lack human immune components that mimic the tumor microenvironment to investigate drug potency and limitations of efficacy. Herein, we describe an ex vivo pleu
Externí odkaz:
https://doaj.org/article/7be4814aaa4240e585a4de85b2acbf5b
Autor:
Wookjin Choi, Chia-Ju Liu, Sadegh Riyahi Alam, Jung Hun Oh, Raj Vaghjiani, John Humm, Wolfgang Weber, Prasad S. Adusumilli, Joseph O. Deasy, Wei Lu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5601-5608 (2023)
Lung adenocarcinoma (ADC) is the most common non-small cell lung cancer. Surgical resection is the primary treatment for early-stage lung ADC while lung-sparing surgery is an alternative for non-aggressive cases. Identifying histopathologic subtypes
Externí odkaz:
https://doaj.org/article/ccc7c9ef4f244867a22477348bf766b5
Autor:
Michael Offin, Jennifer L. Sauter, Sam E. Tischfield, Jacklynn V. Egger, Shweta Chavan, Nisargbhai S. Shah, Parvathy Manoj, Katia Ventura, Viola Allaj, Elisa de Stanchina, William Travis, Marc Ladanyi, Andreas Rimner, Valerie W. Rusch, Prasad S. Adusumilli, John T. Poirier, Marjorie G. Zauderer, Charles M. Rudin, Triparna Sen
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Diffuse pleural mesothelioma (DPM) is an aggressive malignancy that, despite recent treatment advances, has unacceptably poor outcomes. Therapeutic research in DPM is inhibited by a paucity of preclinical models that faithfully re
Externí odkaz:
https://doaj.org/article/7bae9e3ad4f54b39847547d219cf9c55
Publikováno v:
Molecular Therapy: Oncolytics, Vol 25, Iss , Pp 330-334 (2022)
Externí odkaz:
https://doaj.org/article/465361a05cf64354906b3d20c20e7245
Autor:
Navin K. Chintala, Jennie K. Choe, Erin McGee, Rebecca Bellis, Jasmeen K. Saini, Srijita Banerjee, Andre L. Moreira, Marjorie G. Zauderer, Prasad S. Adusumilli, Valerie W. Rusch
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe attenuated, genetically engineered vaccinia virus has been shown to be a promising oncolytic virus for the treatment of patients with solid tumors, through both direct cytotoxic and immune-activating effects. Whereas systemically admini
Externí odkaz:
https://doaj.org/article/3273ec9012d64f429fc5aadf18ca215f
Autor:
Yasushi Kimura, Mario Ghosn, Waseem Cheema, Prasad S. Adusumilli, Stephen B. Solomon, Govindarajan Srimathveeralli
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 194-204 (2022)
Adoptive cell therapy with chimeric antigen receptors (CAR) T cells has proven effective for hematologic malignancies, but success in solid tumors has been impeded by poor intratumoral infiltration, exhaustion of effector cells from antigen burden, a
Externí odkaz:
https://doaj.org/article/abcc1b7dbe8644b8be3a72c1374bb022
Autor:
Andreas Rimner, MD, Prasad S. Adusumilli, MD, Michael D. Offin, MD, Stephen B. Solomon, MD, Etay Ziv, MD, Sara A. Hayes, MD, Michelle S. Ginsberg, MD, Jennifer L. Sauter, MD, Daphna Y. Gelblum, MD, Annemarie F. Shepherd, MD, David M. Guttmann, MD, Jordan E. Eichholz, MS, Zhigang Zhang, PhD, Erika Ritter, BS, Phillip Wong, PhD, Afsheen N. Iqbal, MD, Robert M. Daly, MD, Azadeh Namakydoust, MD, Henry Li, BS, Megan McCune, BS, Emily H. Gelb, BS, Neil K. Taunk, MD, Donata von Reibnitz, MD, Neelam Tyagi, PhD, Ellen D. Yorke, PhD, Valerie W. Rusch, MD, Marjorie G. Zauderer, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 1, Pp 100440- (2023)
Introduction: Single-agent monoclonal antibody therapy against programmed death-ligand 1 (PD-L1) has modest effects in malignant pleural mesothelioma. Radiation therapy can enhance the antitumor effects of immunotherapy. Nevertheless, the safety of c
Externí odkaz:
https://doaj.org/article/8350f1d8ba0d4d41ad97457d20805a67
Autor:
Xiuyan Wang, Oriana Borquez-Ojeda, Jolanta Stefanski, Fang Du, Jinrong Qu, Jagrutiben Chaudhari, Keyur Thummar, Mingzhu Zhu, Ling-bo Shen, Melanie Hall, Paridhi Gautam, Yongzeng Wang, Brigitte Sénéchal, Devanjan Sikder, Prasad S. Adusumilli, Renier J. Brentjens, Kevin Curran, Mark B. Geyer, Sham Mailankhody, Roisin O’Cearbhaill, Jae H. Park, Craig Sauter, Susan Slovin, Eric L. Smith, Isabelle Rivière
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 377-387 (2021)
With the US Food and Drug Administration (FDA) approval of four CD19- and one BCMA-targeted chimeric antigen receptor (CAR) therapy for B cell malignancies, CAR T cell therapy has finally reached the status of a medicinal product. The successful manu
Externí odkaz:
https://doaj.org/article/ac2a507ac1554df1b9bab28f312a4318