Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Prasad Dande"'
Autor:
Sewanti Limaye, Mohan Menon, Shambhavi Singh, Pritam Kataria, Aditya V. Shreenivas, Rajan Datar, Darshana Patil, Prashant Kumar, Niyati Shah, Hardik Sheth, Suku Sneha, Chetan Madre, Ruturaj Deshpande, Narayan K. Menon, Prasad Dandekar, Vijay Haribhakti
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 3, Pp 171-177 (2024)
Externí odkaz:
https://doaj.org/article/ce0a692af1a740f8a75c22fdae69b2d7
Autor:
Chelsey N. Rolando, Phillip W. Carter, Edward E. Remsen, Daniel K. Turner, Ashley E. Wayman, Prasad Dande
Publikováno v:
Applied Spectroscopy. 67:692-698
The preparation of glass cell surfaces that are chemically functionalized with poly(ethylene glycol) (PEG) chains to reduce sample adsorption and their use in fluorescence correlation spectroscopy (FCS) is described. Optical glass coverslips were aci
Autor:
Brian M. Hoffman, Carl M. Blumenfeld, Todd Wielgos, Prasad Dande, Anthony G. M. Barrett, Sharon Pokropinski, Ton That Hai, Evan R. Trivedi
Publikováno v:
Tetrahedron Letters. 53:5475-5478
We report the synthesis of the near infrared (NIR) fluorescent porphyrazine (Pz) 285, with pendant hydroxyl groups, as a non-toxic platform for delivery of conjugated chemotherapeutic agents to tumor cells. Conjugation of Pz 285 to Doxorubicin via an
Autor:
Balkrishen Bhat, Hans Gaus, Russell Jarres, Andreas Berdeja, Namir Sioufi, Prasad Dande, Eric E. Swayze, Richard H. Griffey, Thazha P. Prakash
Publikováno v:
Journal of Medicinal Chemistry. 49:1624-1634
A systematic structure-activity relationship study of 4'-thioribose containing small interfering RNAs (siRNAs) has led to the identification of highly potent and stable antisense constructs. To enable this optimization effort for both in vitro and in
Autor:
Philip A. Burns, Fa Xian Chen, Gina B. Scott, Prasad Dande, Alberto Inga, Paola Monti, Angelo Abbondandolo, Jack D. Kelly, Gilberto Fronza, Barry Gold, Dharini Shah, Anna Aprile
Publikováno v:
Journal of Biological Chemistry. 274:18327-18334
Me-lex, a methyl sulfonate ester appended to a neutral N-methylpyrrolecarboxamide-based dipeptide, was synthesized to preferentially generate N3-methyladenine (3-MeA) adducts which are expected to be cytotoxic rather than mutagenic DNA lesions. In th
Autor:
William Y. Ellis, Wilbur K. Milhous, Robert G. Ridley, Prasad Dande, Lucia Gerena, Edwin O. Nuzum, Jonathan L. Vennerstrom, Robert E. Miller, Arnulf Dorn
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:598-602
From the Walter Reed Army Institute of Research (WRAIR) inventory, thirteen 8-aminoquinoline analogs of primaquine were selected for screening against a panel of seven Plasmodium falciparum clones and isolates. Six of the 13 8-aminoquinolines had ave
Autor:
Prasad Dande, Barry Gold, Gangning Liang, Fa-Xian Chen, Christopher Switzer, Christopher Roberts, Marek G. Nelson, Hiromasa Hashimoto
Publikováno v:
Biochemistry. 36:6024-6032
The incorporation of zwitterionic residues (5-substituted omega-aminoalkyl-2'-deoxypyrimidines) into DNA has been reported to bend DNA as measured by aberrant gel mobility [Strauss et al. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 9515-9520]. Herein we
Autor:
Timothy A. Vickers, Russell Jarres, Namir Sioufi, Brenda F. Baker, Richard H. Griffey, Thazha P. Prakash, Balkrishen Bhat, Charles R. Allerson, Prasad Dande, Eric E. Swayze
Publikováno v:
Journal of medicinal chemistry. 48(13)
A systematic study on the effect of 2'-sugar modifications (2'-F (2'-F-2'-deoxy-nucleoside residues), 2'-O-Me (2'-O-methyl-nucleoside residues), and 2'-O-MOE [2'-O-(2-methoxyethyl)]-nucleoside residues) in the antisense and sense strands of short int
Autor:
Anne B. Eldrup, Michele Bosserman, Bohdan S. Wolanski, Steven S. Carroll, Robert L. Lafemina, Joanne E Tomassini, Lawrence F. Colwell, Thazha P. Prakash, Neelima Bhat, C. Frank Bennett, David B. Olsen, Joseph Leone, P. Dan Cook, Balkrishen Bhat, Christine Burlein, Osvaldo A. Flores, Malcolm MacCoss, Daniel R. McMasters, Prasad Dande, Marija Prhavc, Sanjib Bera, Quanlai Song, Derek Von Langen, Krista Getty, John F. Fay, Jennifer L. Brooks, Richard G Ball
Publikováno v:
Journal of medicinal chemistry. 47(21)
Hepatitis C virus infection constitutes a significant health problem in need of more effective therapies. We have recently identified 2'-C-methyladenosine and 2'-C-methylguanosine as potent nucleoside inhibitors of HCV RNA replication in vitro. Howev
Autor:
Samuel Settles, Barry Gold, Dharini Shah, Gilberto Fronza, Fa Xian Chen, Sridhar Varadarajan, Prasad Dande
Publikováno v:
Biochemistry. 42(48)
Minor groove specific DNA equilibrium binding peptides (lex) based on N-methylpyrrole-carboxamide and/or N-methylimidazolecarboxamide subunits have been modified with an O-methyl sulfonate ester functionality to target DNA methylation in the minor gr