Alkaloid-based modulators of the PI3K/Akt/mTOR pathway for cancer therapy: Understandings from pharmacological point of view.

Autor: Mokhfi FZ; Laboratory of AgroBiotechnology and Nutrition in Semi Arid Zones, Faculty of Nature and Life Sciences, University of Ibn Khaldoun, Tiaret, Algeria., Al Amin M; Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, 1207, Bangladesh., Zehravi M; Department of Clinical Pharmacy, College of Dentistry & Pharmacy, Buraydah Private Colleges, Buraydah, 51418, Saudi Arabia. Electronic address: mahrukh.zehravi@hotmail.com., Sweilam SH; Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia; Department of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Cairo-Suez Road, Badr City, Cairo, 11829, Egypt., Arjun UVNV; Vels Institute of Science, Technology and Advanced Studies (VISTAS), PV Vaithiyalingam Rd, Velan Nagar, Krishna Puram, Pallavaram, Chennai, 600117, Tamil Nadu, India., Gupta JK; Institute of Pharmaceutical Research, GLA University Mathura, Uttar Pradesh, India., Vallamkonda B; Department of Pharmaceutical Science, School of Applied Sciences and Humanities, VIGNAN'S Foundation for Science, Technology & Research, Vadlamudi, Andhra Pradesh, India., Balakrishnan A; Department of Pharmaceutics, GRT Institute of Pharmaceutical Education and Research, Tiruttani, Tamil Nadu, India., Challa M; Department of Pharmaceutics, Vasavi Institute of Pharmaceutical Sciences, Vasavi Nagar, Peddapalli Village, Sidhout Mandal Kadapa District, Andhra Pradesh, India., Singh J; School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India., Prasad PD; Depertment of Pharmacology, Mohan Babu University, MB School of Pharmaceutical Sciences, (Erstwhile, Sree Vidyaniketan College of Pharmacy), Tirupati, India., Ali SS; Lloyd Institute of Management and Technology, Plot No.-11, Knowledge Park-II, Greater Noida, Uttar Pradesh, 201306, India., Ahmad I; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia., Doukani K; Department of Biology, Faculty of Nature and Life Sciences, University of Ibn Khaldoun, Tiaret, Algeria., Emran TB; Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, 1207, Bangladesh; Department of Pathology and Laboratory Medicine and Legorreta Cancer Center Warren Alpert Medical School, Brown University, Providence, RI, 02912, USA; Legorreta Cancer Center, Brown University, Providence, RI 02912, USA. Electronic address: talha_bin_emran@brown.edu.

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2024 Oct 01; Vol. 402, pp. 111218. Date of Electronic Publication: 2024 Aug 28.

Revolutionizing Diabetes Care: The Role of Marine Bioactive Compounds and Microorganisms.

Autor: Reddy KTK; Department of Pharmacy, University College of Technology, Osmania University, Amberpet, Hyderabad, Telangana, India., Rakesh K; Department of Chemistry, Koneru Lakshmaiah Education Foundation, Greenfields, Vaddeswaram, Guntur, Andhra Pradesh, India., Prathyusha S; Department of Pharmacognosy, School of Pharmacy, Guru Nanak Institutions Technical Campus, Hyderabad, India., Gupta JK; Department of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, Chaumuhan, Uttar Pradesh, India., Nagasree K; Department of Regulatory Affairs, Samskruthi College of Pharmacy Samskruti College of Pharmacy, Ghatkesar, Telangana, India., Lokeshvar R; Department of Pharmacology, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Saveetha Nagar, Thandalam, Chennai, India., Elumalai S; Department of Quality Control, Ambiopharm Inc, Dittman Ct, Beach Island, South Carolina, 29842, USA., Prasad PD; Department of Pharmacology, Mohan Babu University, MB School of Pharmaceutical Sciences, (Erstwhile, Sree Vidyaniketan College of Pharmacy), Tirupati, India., Kolli D; Department of Chemistry, Koneru Lakshmaiah Education Foundation, Greenfields, Vaddeswaram, Guntur, Andhra Pradesh, India. atluri.deepti1984@gmail.com.

Publikováno v: Cell biochemistry and biophysics [Cell Biochem Biophys] 2024 Sep 10. Date of Electronic Publication: 2024 Sep 10.

The Transcription Factor RXRα in CD11c+ APCs Regulates Intestinal Immune Homeostasis and Inflammation.

Autor: Manoharan I; Georgia Cancer Center, Augusta University, Augusta, GA.; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, GA., Shanmugam A; Georgia Cancer Center, Augusta University, Augusta, GA., Ramalingam M; Georgia Cancer Center, Augusta University, Augusta, GA., Patel N; Department of Pathology, Augusta University, Augusta, GA., Thangaraju M; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, GA., Ande S; Georgia Cancer Center, Augusta University, Augusta, GA.; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, GA., Pacholczyk R; Georgia Cancer Center, Augusta University, Augusta, GA., Prasad PD; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, GA., Manicassamy S; Georgia Cancer Center, Augusta University, Augusta, GA.; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, GA.; Department of Medicine, Augusta University, Augusta, GA.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2023 Sep 01; Vol. 211 (5), pp. 853-861.

RAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy.

Autor: Bridges AE; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia., Ramachandran S; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas., Tamizhmani K; Experimental Medicine, McGill University, Montreal, Quebec, Canada., Parwal U; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia., Lester A; Department of Undergraduate Health Professions, College of Allied Health Sciences, Augusta University, Augusta, Georgia., Rajpurohit P; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia., Morera DS; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia., Hasanali SL; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia., Arjunan P; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Department of Periodontics, Medical College of Georgia, Augusta University, Augusta, Georgia., Jedeja RN; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia., Patel N; Department of Pathology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia., Martin PM; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Department of Opthalmology, Medical College of Georgia, Augusta University, Augusta, Georgia.; James and Jean Culver Vision Discovery Institute, Medical College of Georgia, Augusta University, Augusta, Georgia., Korkaya H; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia., Singh N; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia., Manicassamy S; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia., Prasad PD; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia., Lokeshwar VB; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia., Lokeshwar BL; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia., Ganapathy V; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia.; Department of Cell Biology and Biochemistry, Texas Tech University Health Sciences Center, Lubbock, Texas., Thangaraju M; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, Georgia. mthangaraju@augusta.edu.; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, Georgia.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2021 Sep; Vol. 19 (9), pp. 1486-1497. Date of Electronic Publication: 2021 Jun 07.

Lactate-Dependent Regulation of Immune Responses by Dendritic Cells and Macrophages.

Autor: Manoharan I; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA, United States.; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, United States., Prasad PD; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, United States., Thangaraju M; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, United States., Manicassamy S; Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA, United States.; Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, United States.; Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Jul 29; Vol. 12, pp. 691134. Date of Electronic Publication: 2021 Jul 29 (Print Publication: 2021).