Zobrazeno 1 - 10 of 143 pro vyhledávání: '"Prasad, Koduru"'
1
Akademický článek
Structural screening and molecular simulation identify potential ligands against the K700E hot spot variant and functional pockets of SF3B1 to modulate splicing in myelodysplastic syndrome
Autor: Rolando García, Murat Atis, Andrew Cox, Prasad Koduru
Publikováno v: Heliyon, Vol 10, Iss 12, Pp e32729- (2024)
Myelodysplastic syndrome (MDS), a blood disorder with ineffective hematopoiesis and risk of transformation to acute myeloid leukemia, is characterized by recurring cytogenetic and molecular alterations. By chromosome analysis, approximately 60% of pa
Externí odkaz: https://doaj.org/article/ee25867e378f4d1aa8233999685d5bf9
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2
Akademický článek
RNASeq Analysis for Accurate Identification of Fusion Partners in Tumor Specific Translocations Detected by Standard FISH Probes in Hematologic Malignancies
Autor: Prasad Koduru, Weina Chen, Franklin Fuda, Gurbakhash Kaur, Farrukh Awan, Samuel John, Rolando Garcia, Jeffrey Gagan
Publikováno v: Clinical Pathology, Vol 17 (2024)
Background: Fluorescence labeled DNA probes and in situ hybridization methods had shorter turn round time for results revolutionized their clinical application. Signals obtained from these probes are highly specific, yet they can produce fusion signa
Externí odkaz: https://doaj.org/article/b37f82ec1fd5451bbbc701e938ca0b58
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3
Akademický článek
Genomic heterogeneity within B/T mixed phenotype acute leukemia in a context of an immunophenotype
Autor: Ruifang Zheng, Franklin Fuda, Jeffrey R. Gagan, Olga K. Weinberg, Prasad Koduru, Miguel Cantu, Kathleen Ludwig, Jamie M. Truscott, Robert Collins, Stephen Chung, Yazan F. Madanat, Weina Chen
Publikováno v: Leukemia Research Reports, Vol 21, Iss , Pp 100410- (2024)
B/T mixed phenotype acute leukemia (MPAL) is a rare aggressive leukemia. Three cases of B/T MPAL were identified with comprehensive immunophenotypic, cytogenetic, and molecular studies. T-lineage predominant B/T MPAL shares a genetic signature with T
Externí odkaz: https://doaj.org/article/29321a2d531d4336987fdcd870ed2b8c
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7
Akademický článek
An artificial intelligence system applied to recurrent cytogenetic aberrations and genetic progression scores predicts MYC rearrangements in large B‐cell lymphoma
Autor: Rolando García, Anas Hussain, Weina Chen, Kathleen Wilson, Prasad Koduru
Publikováno v: eJHaem, Vol 3, Iss 3, Pp 707-721 (2022)
Abstract Diffuse large B‐cell lymphoma (DLBCL), the most common type of non‐Hodgkin lymphoma, is characterized by MYC rearrangements (MYC R) in up to 15% of cases, and these have unfavorable prognosis. Due to cryptic rearrangements and variations
Externí odkaz: https://doaj.org/article/88a388d4515c40d3aa77c38f2f58c4bf
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8
Akademický článek
Circulating dividing plasma cells with giant dumbbell‐shaped nuclei
Autor: Elisa Lin, Prasad Koduru, Mingyi Chen
Publikováno v: eJHaem, Vol 2, Iss 4, Pp 867-868 (2021)
Externí odkaz: https://doaj.org/article/25e49cb86a7841b886e29fd05bb721db
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