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Efficient intracellular delivery of native proteins

Autor: D'Astolfo, Diego S, Pagliero, Romina J, Pras, Anita, Karthaus, Wouter R, Clevers, Hans, Prasad, Vikram, Lebbink, Robert Jan, Rehmann, Holger, Geijsen, Niels, Onderzoek, CSCA TR1, Regenerative Medicine, Stem Cells & Cancer

Publikováno v: Cell, 161(3), 674-90. Elsevier B.V.
Cell, 161(3), 674. Cell Press

SummaryModulation of protein function is used to intervene in cellular processes but is often done indirectly by means of introducing DNA or mRNA encoding the effector protein. Thus far, direct intracellular delivery of proteins has remained challeng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7f38ab904b7fcdfd5adbc08051b923
https://pure.knaw.nl/portal/en/publications/7b74f9df-6f8e-4570-871c-1d1ed0915926

Efficient intracellular delivery of native proteins.

Autor: D'Astolfo DS; KNAW-Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., Pagliero RJ; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., Pras A; KNAW-Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands., Karthaus WR; KNAW-Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., Clevers H; KNAW-Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., Prasad V; Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA., Lebbink RJ; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., Rehmann H; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands., Geijsen N; KNAW-Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands; University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, the Netherlands. Electronic address: n.geijsen@hubrecht.eu.

Publikováno v: Cell [Cell] 2015 Apr 23; Vol. 161 (3), pp. 674-690.