Výsledky vyhledávání - "Prarthana Joshi"

Akademický článek

A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy.

Autor: William J Dower, Angie Inkyung Park, Alice V Bakker, Steven E Cwirla, Praechompoo Pongtornpipat, Blake M Williams, Prarthana Joshi, Bryan A Baxter, Michael C Needels, Ronald W Barrett

Publikováno v: PLoS ONE, Vol 18, Iss 10, p e0286834 (2023)

Interleukin (IL)-7 is broadly active on T-cell populations, and modified versions have been clinically evaluated for a variety of therapeutic applications, including cancer, lymphopenia, and infectious diseases; and found to be relatively well-tolera

Externí odkaz: https://doaj.org/article/3bd59ccdb97e4f0fb8a0e9145823542e

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A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy

Autor: William J. Dower, Angie Inkyung Park, Alice V. Bakker, Steven E. Cwirla, Praechompoo Pongtornpipat, Blake M. Williams, Prarthana Joshi, Bryan A. Baxter, Michael C. Needels, Ronald W. Barrett

Interleukin (IL)-7 is broadly active on T-cell populations, and modified versions have been clinically evaluated for a variety of therapeutic applications, including cancer, lymphopenia and infectious diseases; and found to be relatively well-tolerat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ff65917a24a1a813fbc673b68412542
https://doi.org/10.1101/2023.05.24.542196

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Stepup Switched Capacitor Multilevel Inverter With 15 Steps

Autor: Prarthana Joshi, Ruchir Raval, Neha Shah, Shaily Shah, Ankit Sharma

Publikováno v: 2021 International Conference on Intelligent Technologies (CONIT).

In this paper, Novel topology of Multi-Level Inverter which is switched capacitor technique with 15 level is proposed. Generalized structure of this topology is discussed further. Stage by stage 15 level generation in stepped format is also presented

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49ff734a74a738ab47311a3be5c7f0ec
https://doi.org/10.1109/conit51480.2021.9498551

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Abstract 2066: In vitro and in vivo properties of MDK703: An Fc-peptide fusion IL-7Rαγc agonist unrelated in structure to IL-7

Autor: Angie I. Park, Steven E. Cwirla, Alice V. Bakker, Blake M. Williams, Prarthana Joshi, Praechompoo Pongtornpipat, Sandra M. Wang, Bryan Baxter, Michael C. Needels, Ronald W. Barrett, William J. Dower

Publikováno v: Cancer Research. 82:2066-2066

Background: IL-7 receptor activation is essential for the proper development and homeostasis of T-cell subpopulations, and maintenance of the TCR clonal repertoire. Emerging evidence indicates potential clinical utility of IL-7 for immunotherapy of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ad7d9c234b8b182dd62d13430c7bf46
https://doi.org/10.1158/1538-7445.am2022-2066

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567 MDK1319/MDK-701: A potent fully efficacious peptidyl agonist of IL-7Rαγc, designed with no reference to cytokine or receptor structure and unrelated to IL-7, fused to an Fc-domain for PK enhancement

Autor: Ronald W. Barrett, Bakker Alice, Praechompoo Pongtornpipat, Blake Williams, Michael C. Needels, Steven E. Cwirla, Prarthana Joshi, William J. Dower, Sandra Wang

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

Background IL-7 receptor activation is essential for the proper development and homeostasis of T-cell subpopulations, and maintenance of the TCR clonal repertoire. Emerging evidence indicates potential clinical utility of IL-7 for immunotherapy of ly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1870a9c8a04ce0816bd5523b07b5d828
https://doaj.org/article/39219be9b5974bbeaf2f38cc3bb3e06a

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