Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Praphasri, Suphakun"'
Autor:
Kiattawee Choowongkomon, Chanin Nantasenamat, Nattakarn Pobsuk, Supa Hannongbua, Praphasri Suphakun, M. Paul Gleeson
Publikováno v:
Medicinal Chemistry. 15:693-704
Background: Despite the development of extensive control strategies and treatment options, approximately 200 million malaria cases, leading to approximately 450,000 deaths, were reported in 2015. Due to issue of disease resistance, additional drug de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b464fd1aaa01b6ee8db058eefc11b00
https://doi.org/10.2174/1573406415666181219100307
https://doi.org/10.2174/1573406415666181219100307
Autor:
Tamkeen Urooj Paracha, Praphasri Suphakun, Nattapas Salaloy, Kiattawee Choowongkomon, Krongkarn Chootip, M. Paul Gleeson, Kornkanok Ingkaninan, Supa Hannongbua, Nattiya Chaichamnong, Nattakarn Pobsuk, Dumrongsak Pekthong
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:267-270
We describe the design, synthesis and evaluation of a series of N2,N4-diaminoquinazoline analogs as PDE5 inhibitors. Twenty compounds were prepared and these were assessed in terms of their PDE5 and PDE6 activity, ex-vivo vasodilation response, mamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deaa7b7c281433ae68b46c438f7e40da
https://doi.org/10.1016/j.bmcl.2018.11.043
https://doi.org/10.1016/j.bmcl.2018.11.043
Autor:
Kiattawee Choowongkomon, Chatchakorn Eurtivong, Kannika Thongkhao, Praphasri Suphakun, Matthew Paul Gleeson, Lueacha Tabtimmai, Phongphat Obounchoey
Publikováno v:
Journal of Cellular Biochemistry. 120:3353-3361
The epidermal growth factor receptor (EGFR) was found to be overexpressed in several cancers, especially in lung cancers. Finding new effective drug against EGFR is the key to cancer treatment. In this study, the GOLD docking algorithm was used to vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ee5c870aef016c8503cfc5f536e54
https://doi.org/10.1002/jcb.27605
https://doi.org/10.1002/jcb.27605
Autor:
Sucheewin Krobthong, Kiattawee Choowongkomon, Pawitrabhorn Samutrtai, Buabarn Kuaprasert, Praphasri Suphakun, Yodying Yingchutrakul
Publikováno v:
Food Bioscience. 41:101093
Lingzhi (Ganoderma lucidum) is an oriental fungus used as a traditional Chinese medicine. To study the distribution of protein of Lingzhi, synchrotron radiation based FTIR was chosen to identify a rich-protein region. Lingzhi was subsequently hydroly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::438e46235ee64250c3c5e7712f95345d
https://doi.org/10.1016/j.fbio.2021.101093
https://doi.org/10.1016/j.fbio.2021.101093
Autor:
M. Paul Gleeson, Praphasri Suphakun, Borvornwat Toviwek, Supa Hannongbua, Kiattawee Choowongkomon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:4749-4754
Reported herein are efforts to profile 4-aryl- N -phenylpyrimidin-2-amines in terms of their anti-cancer activity towards non small-cell lung carcinoma (NSCLC) cells. We have synthesized new 4-aryl- N -phenylpyrimidin-2-amines and assessed them in te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba66d46a27f4718509d4b4e7b65e8f34
https://doi.org/10.1016/j.bmcl.2017.08.063
https://doi.org/10.1016/j.bmcl.2017.08.063
Autor:
Pimonwan Srisook, Duangnapa Kiriwan, Wanpen Chaicumpa, Kiattawee Choowongkomon, Siratcha Phanthong, Pichamon Kiatwuthinon, Lueacha Tabtimmai, Praphasri Suphakun
Publikováno v:
Journal of cellular biochemistry. 120(10)
Most patients suffering from non-small cell lung cancer (NSCLC) have epidermal growth factor receptor (EGFR) overexpression. Currently, EGFR tyrosine kinase inhibitors (TKIs) that act as the ATP-analogs and monoclonal antibodies (MAbs) to EGFR-ectodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d65071300785fa216ce15b47b1077f
https://pubmed.ncbi.nlm.nih.gov/31172597
https://pubmed.ncbi.nlm.nih.gov/31172597
Autor:
Tamkeen Urooj, Paracha, Nattakarn, Pobsuk, Nattapas, Salaloy, Praphasri, Suphakun, Dumrongsak, Pekthong, Supa, Hannongbua, Kiattawee, Choowongkomon, Nantaka, Khorana, Prapapan, Temkitthawon, Kornkanok, Ingkaninan, M Paul, Gleeson, Krongkarn, Chootip
Publikováno v:
Molecules
Pulmonary arterial hypertension (PAH) is a rare and progressive disease arising from various etiologies and pathogenesis. PAH decreases life expectancy due to pulmonary vascular remodeling, elevation of mean pulmonary arterial pressure, and ultimatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a783e37281212ca2c3a5d5e9bd6c206a
https://pubmed.ncbi.nlm.nih.gov/30646523
https://pubmed.ncbi.nlm.nih.gov/30646523
Autor:
Nattakarn, Pobsuk, Tamkeen Urooj, Paracha, Nattiya, Chaichamnong, Nattapas, Salaloy, Praphasri, Suphakun, Supa, Hannongbua, Kiattawee, Choowongkomon, Dumrongsak, Pekthong, Krongkarn, Chootip, Kornkanok, Ingkaninan, M Paul, Gleeson
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(2)
We describe the design, synthesis and evaluation of a series of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea7d3eaf88332d7a3fc6f46ebda72a68
https://pubmed.ncbi.nlm.nih.gov/30509781
https://pubmed.ncbi.nlm.nih.gov/30509781
Autor:
Matthew Paul Gleeson, Oraphan Phuangsawai, Siriruk Rattanabunyong, Kiattawee Choowongkomon, Praphasri Suphakun, Patcharaporn Khajondetchairit
Publikováno v:
Chemical biologydrug design. 90(5)
A series of 2-amino-aryl-7-aryl-benzoxazole derivatives have been designed, synthesized, and evaluated as anticancer agents. Fourteen of the compounds exhibited cytotoxic effects toward human A549 lung cancer cells. We found 12l was the most potent w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e348e663c565ebc27210b4120eefc5d6
https://pubmed.ncbi.nlm.nih.gov/28544428
https://pubmed.ncbi.nlm.nih.gov/28544428
Autor:
Tamkeen Urooj Paracha, Nattapas Salaloy, Kiattawee Choowongkomon, Krongkarn Chootip, Nattakarn Pobsuk, Kornkanok Ingkaninan, Dumrongsak Pekthong, Supa Hannongbua, Praphasri Suphakun, Prapapan Temkitthawon, Nantaka Khorana, M. Paul Gleeson
Publikováno v:
Molecules
Volume 24
Issue 2
Volume 24
Issue 2
Pulmonary arterial hypertension (PAH) is a rare and progressive disease arising from various etiologies and pathogenesis. PAH decreases life expectancy due to pulmonary vascular remodeling, elevation of mean pulmonary arterial pressure, and ultimatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2262d35de5b4f6ab0d6515a039b9f04
https://doi.org/10.3390/molecules24020281
https://doi.org/10.3390/molecules24020281