Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Pranitha Vangala"'
Autor:
Julius O. Nyalwidhe, Agata Jurczyk, Basanthi Satish, Sambra Redick, Natasha Qaisar, Melanie I. Trombly, Pranitha Vangala, Riccardo Racicot, Rita Bortell, David M. Harlan, Dale L. Greiner, Michael A. Brehm, Jerry L. Nadler, Jennifer P. Wang
Publikováno v:
Microorganisms, Vol 8, Iss 2, p 295 (2020)
Enteroviral infections are implicated in islet autoimmunity and type 1 diabetes (T1D) pathogenesis. Significant β-cell stress and damage occur with viral infection, leading to cells that are dysfunctional and vulnerable to destruction. Human stem ce
Externí odkaz:
https://doaj.org/article/1e949cec547b495a95f084103d562d02
Autor:
Manuel Garber, Andrea Reboldi, Leslie J Berg, Michael P. Gallagher, Pranitha Vangala, James M Conley
Publikováno v:
Proc Natl Acad Sci U S A
The strength of peptide:MHC interactions with the T cell receptor (TCR) is correlated with the time to first cell division, the relative scale of the effector cell response, and the graded expression of activation-associated proteins like IRF4. To re
Autor:
Michael P. Gallagher, Leslie J. Berg, James M. Conley, Andrea Reboldi, Manuel Garber, Pranitha Vangala
The strength of peptide:MHC interactions with the T cell receptor (TCR) is correlated with the time to first cell division, the relative scale of the effector cell response, and the graded expression of activation-associated proteins like IRF4. To re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f450f86fa0bb822741a13fe48b910963
https://doi.org/10.1101/2020.11.12.380725
https://doi.org/10.1101/2020.11.12.380725
Autor:
Junling Wang, Pengpeng Liu, Alex K. Shalek, Pranitha Vangala, Patrick McDonel, Jose Ordovas-Montanes, Elisa Donnard, Manuel Garber, Robert W. Finberg, Zhiru Guo, Yueying Cao
Influenza virus infections are major causes of morbidity and mortality. Research using cultured cells, bulk tissue, and animal models cannot fully capture human disease dynamics. Many aspects of virus-host interactions in a natural setting remain unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb1f203f071b0d8630df35d1140cf4d
https://doi.org/10.1101/2020.04.15.042978
https://doi.org/10.1101/2020.04.15.042978
Autor:
Kenneth L. Rock, Benjamin J Chen, Pranitha Vangala, Paul Meraner, Manuel Garber, Abraham L. Brass, Barry A. Kriegsman
Publikováno v:
J Immunol
To arise and progress, cancers need to evade immune elimination. Consequently, progressing tumors are often MHC class I (MHC-I) low and express immune inhibitory molecules, such as PD-L1, which allows them to avoid the main antitumor host defense, CD
Autor:
Kyle Gellatly, JeanMarie Houghton, Sean M. McCauley, Kyusik Kim, Kathleen Busman-Sahay, Steven G. Deeks, Thomas C. Greenough, Alan G. Derr, Jeremy Luban, Pranitha Vangala, Smita Jaiswal, Ma Somsouk, Yetao Wang, Peter W. Hunt, Carol L. Vinton, Manuel Garber, Lawrence M. Lifshitz, Jacob D. Estes, Jason M. Brenchley, Alper Kucukural, Patrick McDonel
Publikováno v:
Nature immunology, vol 21, iss 3
Nature immunology
Nature immunology
Human immunodeficiency virus 1 (HIV-1) infection is associated with heightened inflammation and excess risk of cardiovascular disease, cancer and other complications. These pathologies persist despite antiretroviral therapy. In two independent cohort
Autor:
Manuel Garber, Kyle Gellatly, Mitchell Guttman, R. Murphy, Sofia A. Quinodoz, Pranitha Vangala, Patrick McDonel
Publikováno v:
Mol Cell
Eukaryotic gene expression regulation involves thousands of distal regulatory elements. Understanding the quantitative contribution of individual enhancers to gene expression is critical for assessing the role of disease-associated genetic risk varia
Autor:
Sambra D. Redick, David M. Harlan, Natasha Qaisar, Jennifer P. Wang, Riccardo Racicot, Basanthi Satish, Pranitha Vangala, Agata Jurczyk, Julius O. Nyalwidhe, Dale L. Greiner, Melanie I. Trombly, Michael A. Brehm, Jerry L. Nadler, Rita Bortell
Publikováno v:
Microorganisms
Volume 8
Issue 2
Microorganisms, Vol 8, Iss 2, p 295 (2020)
Volume 8
Issue 2
Microorganisms, Vol 8, Iss 2, p 295 (2020)
Enteroviral infections are implicated in islet autoimmunity and type 1 diabetes (T1D) pathogenesis. Significant &beta
cell stress and damage occur with viral infection, leading to cells that are dysfunctional and vulnerable to destruction. Human
cell stress and damage occur with viral infection, leading to cells that are dysfunctional and vulnerable to destruction. Human
Autor:
Kyle Gellatly, Thomas C. Greenough, Manuel Garber, Yetao Wang, Pranitha Vangala, Lawrence M. Lifshitz, Sean M. McCauley, Alper Kucukural, Kyusik Kim, Patrick McDonel, Alan G. Derr, JeanMarie Houghton, Jeremy Luban, Smita Jaiswal
HIV-1-infected people who take medications that suppress viremia, preserve CD4+ T cells, and prevent AIDS, have chronic inflammation with increased cardiovascular mortality. To investigate the etiology of this inflammation, the effect of HIV-1 on inn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c317be9ec02ef4d727675f720cd1c3
https://doi.org/10.1101/221010
https://doi.org/10.1101/221010
Autor:
Pranitha Vangala, Karen Gallagher-Dorval, Sarah M. Nicoloro, Yuefei Shen, Joseph C. Yawe, Jessica Cohen, Richard A. Perugini, Michaela Tencerova, Olga T. Gupta, David J. Pedersen, Lorena Garcia-Menendez, Michael P. Czech, Myriam Aouadi
Publikováno v:
The FASEB Journal. 29:2959-2969
Obesity promotes insulin resistance associated with liver inflammation, elevated glucose production, and type 2 diabetes. Although insulin resistance is attenuated in genetic mouse models that suppress systemic inflammation, it is not clear whether l