Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Praneeth Sudalagunta"'
Autor:
Ryan T. Bishop, Tao Li, Raghunandan R. Alugubelli, Mostafa Nasr, Karl J. Nyman, Praneeth Sudalagunta, Mark Meads, Jeremy Frieling, Niveditha Nerlakanti, Marilena Tauro, Oliver Hampton, Bin Fang, Steven Grant, John Koomen, Ariosto Siqueira Silva, Kenneth H. Shain, Conor C. Lynch
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100539- (2024)
Externí odkaz:
https://doaj.org/article/521fc9dd9d7d46f098490ae18ec77b15
Autor:
AGM Mostofa, Allison Distler, Mark B. Meads, Eva Sahakian, John J. Powers, Alexandra Achille, David Noyes, Gabriela Wright, Bin Fang, Victoria Izumi, John Koomen, Rupal Rampakrishnan, Tuan P. Nguyen, Gabriel De Avila, Ariosto S. Silva, Praneeth Sudalagunta, Rafael Renatino Canevarolo, Maria D. Coelho Siqueira Silva, Raghunandan Reddy Alugubelli, Hongyue A. Dai, Amit Kulkarni, William S. Dalton, Oliver A. Hampton, Eric A. Welsh, Jamie K. Teer, Alexandre Tungesvik, Kenneth L. Wright, Javier Pinilla-Ibarz, Eduardo M. Sotomayor, Kenneth H. Shain, Jason Brayer
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
The clinical utility of histone/protein deacetylase (HDAC) inhibitors in combinatorial regimens with proteasome inhibitors for patients with relapsed and refractory multiple myeloma (MM) is often limited by excessive toxicity due to HDAC inhibitor pr
Externí odkaz:
https://doaj.org/article/7fe4645c54d74f3db9e69957840e8738
Autor:
Praneeth Sudalagunta, Maria C. Silva, Rafael R. Canevarolo, Raghunandan Reddy Alugubelli, Gabriel DeAvila, Alexandre Tungesvik, Lia Perez, Robert Gatenby, Robert Gillies, Rachid Baz, Mark B. Meads, Kenneth H. Shain, Ariosto S. Silva
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Background: Multiagent therapies, due to their ability to delay or overcome resistance, are a hallmark of treatment in multiple myeloma (MM). The growing number of therapeutic options in MM requires high-throughput combination screening tools to bett
Externí odkaz:
https://doaj.org/article/2bfb0dce927d404ba1fd3ed314b63a77
Autor:
Kenneth H. Shain, Mark B. Meads, Eduardo Sontag, Robert Gillies, Robert Gatenby, James Greene, William Dalton, Dmitri Rebatchouk, Lia Perez, Rachid Baz, Christopher Cubitt, Lu Chen, Dung-Tsa Chen, Jinming Song, Tuan Nguyen, Aunshka Collins, Timothy Jacobson, Allison Distler, Praneeth Sudalagunta, Maria C. Silva, Ariosto Silva
Supplemental Figures and Tables to augment (1) the mathematical modeling (providing details on specific therapeutics); (2) patient characteristics (treatment history, clinical and predicted response), (3) synergistic activities identified by EMMA; an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e40fa9a12e6f34c664a5aab099ac88
https://doi.org/10.1158/0008-5472.22413492
https://doi.org/10.1158/0008-5472.22413492
Autor:
Kenneth H. Shain, Mark B. Meads, Eduardo Sontag, Robert Gillies, Robert Gatenby, James Greene, William Dalton, Dmitri Rebatchouk, Lia Perez, Rachid Baz, Christopher Cubitt, Lu Chen, Dung-Tsa Chen, Jinming Song, Tuan Nguyen, Aunshka Collins, Timothy Jacobson, Allison Distler, Praneeth Sudalagunta, Maria C. Silva, Ariosto Silva
Multiple myeloma remains treatable but incurable. Despite a growing armamentarium of effective agents, choice of therapy, especially in relapse, still relies almost exclusively on clinical acumen. We have developed a system, Ex vivo Mathematical Myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c8ea1e40acfd2191f194915500445e
https://doi.org/10.1158/0008-5472.c.6508731.v1
https://doi.org/10.1158/0008-5472.c.6508731.v1
Autor:
Kenneth H. Shain, Mark B. Meads, Eduardo Sontag, Robert Gillies, Robert Gatenby, James Greene, William Dalton, Dmitri Rebatchouk, Lia Perez, Rachid Baz, Christopher Cubitt, Lu Chen, Dung-Tsa Chen, Jinming Song, Tuan Nguyen, Aunshka Collins, Timothy Jacobson, Allison Distler, Praneeth Sudalagunta, Maria C. Silva, Ariosto Silva
Individual patient EMMA predicitons of actual responses to therapy (companion to Figure 3i).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fac539d7d2cfa939c1a8e55b9c83c3
https://doi.org/10.1158/0008-5472.22413495
https://doi.org/10.1158/0008-5472.22413495
Autor:
Qibing Jiang, Praneeth Sudalagunta, Maria C Silva, Rafael R Canevarolo, Xiaohong Zhao, Khandakar Tanvir Ahmed, Raghunandan Reddy Alugubelli, Gabriel DeAvila, Alexandre Tungesvik, Lia Perez, Robert A Gatenby, Robert J Gillies, Rachid Baz, Mark B Meads, Kenneth H Shain, Ariosto S Silva, Wei Zhang
Publikováno v:
Bioinformatics
Motivation Time-lapse microscopy is a powerful technique that relies on images of live cells cultured ex vivo that are captured at regular intervals of time to describe and quantify their behavior under certain experimental conditions. This imaging m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d342328102ae596853ae2f0bf52bce81
https://europepmc.org/articles/PMC9991899/
https://europepmc.org/articles/PMC9991899/
Autor:
Marilena Tauro, Tao Li, Mark Meads, Praneeth Sudalagunta, Raghunandan Reddy Alugubelli, Nicholas Lawrence, Ernst Schonbrunn, Harshani Lawrence, Kenneth Shain, Conor Lynch
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S98-S99
Autor:
Ariosto, Silva, Maria C, Silva, Praneeth, Sudalagunta, Allison, Distler, Timothy, Jacobson, Aunshka, Collins, Tuan, Nguyen, Jinming, Song, Dung-Tsa, Chen, Lu, Chen, Christopher, Cubitt, Rachid, Baz, Lia, Perez, Dmitri, Rebatchouk, William, Dalton, James, Greene, Robert, Gatenby, Robert, Gillies, Eduardo, Sontag, Mark B, Meads, Kenneth H, Shain
Publikováno v:
Cancer Res
Multiple myeloma (MM) remains treatable but incurable. Despite a growing armamentarium of effective agents, choice of therapy, especially in relapse, still relies almost exclusively on clinical acumen. We have developed a system, EMMA (Ex vivo Mathem