Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Pranay D. Khare"'
Autor:
Richard P. Junghans, N. Joseph Espat, Robin Davies, Earle O. Assanah, Brian F. Stainken, Qiangzhong Ma, Mitchell Thorn, Pranay D. Khare, Gary R. Point, Wesley Mooring, Li Juan Wang, Elise McCormack, Rachel A. Burga, Steven C. Katz
Supplemental Figure 1. In vitro cytotoxicity assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e4f36b3128e8a08781410abb288250
https://doi.org/10.1158/1078-0432.22458323
https://doi.org/10.1158/1078-0432.22458323
Autor:
Richard P. Junghans, N. Joseph Espat, Robin Davies, Earle O. Assanah, Brian F. Stainken, Qiangzhong Ma, Mitchell Thorn, Pranay D. Khare, Gary R. Point, Wesley Mooring, Li Juan Wang, Elise McCormack, Rachel A. Burga, Steven C. Katz
Purpose: Chimeric antigen receptor–modified T cells (CAR-T) have demonstrated encouraging results in early-phase clinical trials. Successful adaptation of CAR-T technology for CEA-expressing adenocarcinoma liver metastases, a major cause of death i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c749b8413a71355a55dddb9a20c880e
https://doi.org/10.1158/1078-0432.c.6523904.v1
https://doi.org/10.1158/1078-0432.c.6523904.v1
Autor:
Richard P. Junghans, N. Joseph Espat, Robin Davies, Earle O. Assanah, Brian F. Stainken, Qiangzhong Ma, Mitchell Thorn, Pranay D. Khare, Gary R. Point, Wesley Mooring, Li Juan Wang, Elise McCormack, Rachel A. Burga, Steven C. Katz
Supplemental Figure 4. Cytokine response to treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07639feef77b2ee62051a41eed87b308
https://doi.org/10.1158/1078-0432.22458314
https://doi.org/10.1158/1078-0432.22458314
Autor:
Richard P. Junghans, N. Joseph Espat, Robin Davies, Earle O. Assanah, Brian F. Stainken, Qiangzhong Ma, Mitchell Thorn, Pranay D. Khare, Gary R. Point, Wesley Mooring, Li Juan Wang, Elise McCormack, Rachel A. Burga, Steven C. Katz
Supplemental Figure 3. Radiographic studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc3ca32bc6c13ae1f09ab26cef4d090
https://doi.org/10.1158/1078-0432.22458317
https://doi.org/10.1158/1078-0432.22458317
Autor:
Richard P. Junghans, N. Joseph Espat, Robin Davies, Earle O. Assanah, Brian F. Stainken, Qiangzhong Ma, Mitchell Thorn, Pranay D. Khare, Gary R. Point, Wesley Mooring, Li Juan Wang, Elise McCormack, Rachel A. Burga, Steven C. Katz
Supplemental Figure 2. Flow cytometry gating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa7e5a7eacdefc366bf6ba0e0a7d272
https://doi.org/10.1158/1078-0432.22458320.v1
https://doi.org/10.1158/1078-0432.22458320.v1
Autor:
James Perry, Pranay D. Khare, Mercay Reuter, Daniel B. DeOliveira, Manish Jain, Colleen Winstead, Hubert Lam, Thomas Davis, Ray Stapleton, Jessica B. Flechtner
Publikováno v:
Cancer Immunology Research. 10:P005-P005
Candidate adoptive T cell therapies (ACT), such as tumor infiltrating lymphocyte (TIL) treatments, have resulted in unprecedented and durable efficacy in clinical trials. Despite this, the manufacturing requires viable tumor resection, and TIL expans
Autor:
James R Perry, Mercay Reuter, Victoria L DeVault, Adrienne Li, Harshal Zope, Daniel B DeOliveira, Pranay D Khare, Manish Jain, Colleen J Winstead, Hubert Lam, Jessica Baker Flechtner
Publikováno v:
The Journal of Immunology. 206:58.08-58.08
Adoptive T cell therapy using ex vivo expanded autologous tumor-infiltrating lymphocytes (TIL) has resulted in notable tumor regression across multiple solid tumor indications. Despite their success, TIL harvest requires invasive surgery and sterile
Autor:
Laurence J.N. Cooper, Tim Chan, Pranay D. Khare, Hongliang Cai, John A. Barrett, John Miao, Francois Lebel
Modulating the tumor microenvironment with immuno-stimulatory therapy maybe an attractive approach for the treatment of glioma. We took advantage of IL-12 biology utilizing a replication-incompetent adenovirus (Ad) engineered to conditionally express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961d9a6d1cc445794bdab99ceb731d49
https://europepmc.org/articles/PMC5692647/
https://europepmc.org/articles/PMC5692647/
Autor:
John A. Barrett, Hongliang Cai, Pranay D. Khare, Tim Chan, Paul Gonzales, Laurence J.N. Cooper, Francois Lebel, Jessica Dalsing-Hernandez, John Miao
Successful immunotherapy is dependent on the regulation of an immune response concomitant with modulation of the tumor microenvironment. To study this hypothesis, we utilized a replication-incompetent adenovirus engineered to conditionally express mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9ff7dd1f529b72ed00a12311599598
https://europepmc.org/articles/PMC5693043/
https://europepmc.org/articles/PMC5693043/
Autor:
John A, Barrett, Hongliang, Cai, John, Miao, Pranay D, Khare, Paul, Gonzalez, Jessica, Dalsing-Hernandez, Geeta, Sharma, Tim, Chan, Laurence J N, Cooper, Francois, Lebel
Publikováno v:
Cancer Gene Therapy
The purpose of this study was to determine if localized delivery of IL-12 encoded by a replication-incompetent adenoviral vector engineered to express IL-12 via a RheoSwitch Therapeutic System® (RTS®) gene switch (Ad-RTS-IL-12) administered intratu