Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pranay, Jakkula"'
Publikováno v:
ACS Omega, Vol 7, Iss 1, Pp 548-564 (2021)
Externí odkaz:
https://doaj.org/article/5372a486086247ebb26150ca7ea877b0
Autor:
Goud, Nerella Sridhar, Kanth Makani, Venkata Krishna, Pranay, Jakkula, Alvala, Ravi, Qureshi, Insaf A., Kumar, Pardeep, Bharath, Rose Dawn, Nagaraj, Chandana, Yerramsetty, Suresh, Pal-Bhadra, Manika, Alvala, Mallika
Publikováno v:
In Bioorganic Chemistry April 2020 97
Autor:
Goud, Nerella Sridhar, Ghouse, S. Mahammad, Vishnu, Jatoth, Komal, D., Talla, Venu, Alvala, Ravi, Pranay, Jakkula, Kumar, Janish, Qureshi, Insaf A., Alvala, Mallika
Publikováno v:
In Bioorganic Chemistry August 2019 89
Publikováno v:
Applied Microbiology and Biotechnology. 105:5471-5489
6-phosphogluconate dehydrogenase (6PGDH) participates in pentose phosphate pathway of glucose metabolism by catalyzing oxidative decarboxylation of 6-phsophogluconate (6PG) and its absence has been lethal for several eukaryotes. Despite being a valid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20dca1a1130dd6b1e43a26e99f96a908
https://doi.org/10.1007/s00253-021-11434-4
https://doi.org/10.1007/s00253-021-11434-4
Autor:
Bandigi Narsimulu, Rahila Qureshi, Pranay Jakkula, Priti Singh, Mohammed Arifuddin, Insaf Ahmed Qureshi
Publikováno v:
International Journal of Biological Macromolecules. 237:124118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f93fc5ce2dcf8f9f4f7154bc52535f4
https://doi.org/10.1016/j.ijbiomac.2023.124118
https://doi.org/10.1016/j.ijbiomac.2023.124118
Publikováno v:
International Journal of Biological Macromolecules. 152:812-827
The enzyme pyridoxal kinase (PdxK) catalyzes the conversion of pyridoxal to pyridoxal-5'-phosphate (PLP) using ATP as the co-factor. The product pyridoxal-5'-phosphate plays a key role in several biological processes such as transamination, decarboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a083e2b32b1bfa088068a08b5d6adb8e
https://doi.org/10.1016/j.ijbiomac.2020.02.257
https://doi.org/10.1016/j.ijbiomac.2020.02.257
Autor:
Santhosh Gatreddi, Ravi Alvala, Ghouse S. Mahammad, Mallika Alvala, Chandraiah Godugu, Venkatesh Pooladanda, Insaf A. Qureshi, Pranay Jakkula, Nerella Sridhar Goud
Publikováno v:
Chemical Biology & Drug Design. 94:1919-1929
A series of novel morpholines linked coumarin-triazole hybrids (6a-6v) has been synthesized and evaluated for their anti-proliferative potential on a panel of five human cancer cell lines, namely bone (MG-63), lung (A549), breast (MDA-MB-231), colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17681034c5eca284b3796c619ad533ff
https://doi.org/10.1111/cbdd.13578
https://doi.org/10.1111/cbdd.13578
Publikováno v:
Biochemical and Biophysical Research Communications. 516:770-776
Protein phosphorylation, governed by kinases and phosphatases, plays a pivotal role in enormous cellular signaling pathways. Although PPP family of serine/threonine phosphatases have been involved in multiplication and growth of trypanosomatid parasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48316dbca963d74564c718de2e3eff2b
https://doi.org/10.1016/j.bbrc.2019.06.085
https://doi.org/10.1016/j.bbrc.2019.06.085
Autor:
Rahila Qureshi, Pranay Jakkula, Nooruddin Khan, Girish Ch. Panigrahi, Insaf A. Qureshi, K. Amith Kumar
Publikováno v:
International journal of biological macromolecules. 165
Aminoacyl tRNA synthetases (aaRSs) are integral components of protein biosynthesis along with several non-canonical cellular processes. Inhibition studies of aaRSs presented these enzymes as promising drug targets in many pathogens, however aspartyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4962bd8feafc56e199a41e890d1b069d
https://pubmed.ncbi.nlm.nih.gov/33736288
https://pubmed.ncbi.nlm.nih.gov/33736288
Publikováno v:
Molecular and biochemical parasitology. 223
Most of the signaling pathways are regulated by reversible phosphorylation-dephosphorylation which involves enzymes- kinases and phosphatases. Current knowledge about the protein phosphatases in parasites like Trypanosoma and Leishmania is very minim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb1e1c2897f6d2028569a5f44204348
https://pubmed.ncbi.nlm.nih.gov/29964060
https://pubmed.ncbi.nlm.nih.gov/29964060