Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pranav Prem"'
Autor:
Pranav Preman, Daan Moechars, Emre Fertan, Leen Wolfs, Lutgarde Serneels, Disha Shah, Jochen Lamote, Suresh Poovathingal, An Snellinx, Renzo Mancuso, Sriram Balusu, David Klenerman, Amaia M Arranz, Mark Fiers, Bart De Strooper
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 12, Pp 3113-3141 (2024)
Abstract The major genetic risk factor for Alzheimer’s disease (AD), APOE4, accelerates beta-amyloid (Aβ) plaque formation, but whether this is caused by APOE expressed in microglia or astrocytes is debated. We express here the human APOE isoforms
Externí odkaz:
https://doaj.org/article/8623492f8242414195b2b4f5b3e4002e
Autor:
Girish Gopinath, Muhamed Fasil Chettiyam Thodi, Udayar Pillai Surendran, Pranav Prem, Jesiya Nalukudi Parambil, Abed Alataway, Ahmed A. Al-Othman, Ahmed Z. Dewidar, Mohamed A. Mattar
Publikováno v:
Water; Volume 15; Issue 2; Pages: 244
This study concerned the assessment of changes in the coastline of Kavvayi beach and its nine islands in a tropical coastal wetland using remote sensing (RS) data and geographic information systems (GIS), as this sedimentary environment is still poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975cf074620cb6a9108b36f8247949a0
Autor:
Joan Cruz-Sesé, María Alfonso-Triguero, Jon Olano-Bringas, Leire Ruiz, Nuria Galbis, Pranav Preman, An Snellinx, Julia Tcw, Elena Alberdi, Alison Goate, Bart De Strooper, Amaia Mendiguren Arranz
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S389- (2023)
Externí odkaz:
https://doaj.org/article/02ad79ec66c948dc891b323a7d5a67a7
Autor:
Pranav Preman, Amaia M. Arranz
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113129- (2023)
Lee et al.1 report that loss of the Alzheimer’s disease risk factor SORL1 results in neuron-specific reduction in APOE and CLU, altered lipid homeostasis, and increased Aβ levels and phosphorylated Tau, both rescued by stabilizing retromer or enha
Externí odkaz:
https://doaj.org/article/a5358abc981a4e74b2ffa2c3b83efadf
Autor:
Corey Beard, Paul Robertson, Mark R. Giovinazzi, Joseph M. Akana Murphy, Eric B. Ford, Samuel Halverson, Te Han, Rae Holcomb, Jack Lubin, Rafael Luque, Pranav Premnath, Chad F. Bender, Cullen H. Blake, Qian Gong, Howard Isaacson, Shubham Kanodia, Dan Li, Andrea S. J. Lin, Sarah E. Logsdon, Emily Lubar, Michael W. McElwain, Andrew Monson, Joe P. Ninan, Jayadev Rajagopal, Arpita Roy, Christian Schwab, Gudmundur Stefansson, Ryan C. Terrien, Jason T. Wright
Publikováno v:
The Astronomical Journal, Vol 168, Iss 4, p 149 (2024)
We present a new analysis of Kepler-21, the brightest ( V = 8.5) Kepler system with a known transiting exoplanet, Kepler-21 b. Kepler-21 b is a radius valley planet ( R = 1.6 ± 0.2 R _⊕ ) with an Earth-like composition (8.38 ± 1.62 g cm ^–3 ),
Externí odkaz:
https://doaj.org/article/9e8d36f492f74b37afd276b4f75a7811
Autor:
Pranav Preman, Julia TCW, Sara Calafate, An Snellinx, Maria Alfonso-Triguero, Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison M Goate, Bart De Strooper, Amaia M Arranz
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Increasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer’s disease comes from molecular and functional studies in rodent models. However, these models may
Externí odkaz:
https://doaj.org/article/6f6aad58ba3e4327a615115ca66accb3
Publikováno v:
Cells, Vol 10, Iss 3, p 540 (2021)
Astrocytes perform a wide variety of essential functions defining normal operation of the nervous system and are active contributors to the pathogenesis of neurodegenerative disorders such as Alzheimer’s among others. Recent data provide compelling
Externí odkaz:
https://doaj.org/article/4a678b9369e941229a6228c937aef0d1