Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pranav Prabhala"'
Autor:
Seongmin Kim, Arash Naziripour, Pranav Prabhala, Viktor Horváth, Abidemi Junaid, David T. Breault, Girija Goyal, Donald E. Ingber
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104921- (2024)
Summary: Background: Sulfadoxine-pyrimethamine (SP) antimalarial therapy has been suggested to potentially increase the birth weight of infants in pregnant women in sub-Saharan Africa, independently of malarial infection. Here, we utilized female int
Externí odkaz:
https://doaj.org/article/1052d97ecf594f1d99ffcccef20f927c
Autor:
James Logue, Arup R. Chakraborty, Robert Johnson, Girija Goyal, Melissa Rodas, Louis J. Taylor, Lauren Baracco, Marisa E. McGrath, Robert Haupt, Brooke A. Furlong, Mercy Soong, Pranav Prabhala, Viktor Horvath, Kenneth E. Carlson, Stuart Weston, Donald E. Ingber, Melvin L. DePamphilis, Matthew B. Frieman
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Compound-testing in a murine model for COVID-19 show that the prophylactic or therapeutic application of Apilimod and other PIKfyve inhibitors, the former being considered for human Phase II trials, worsens disease outcome with higher lung viral load
Externí odkaz:
https://doaj.org/article/9de19b41ea5f445cb565a156c6a567d3
Autor:
Megan M Sperry, Tomiko T Oskotsky, Ivana Marić, Shruti Kaushal, Takako Takeda, Viktor Horvath, Rani K Powers, Melissa Rodas, Brooke Furlong, Mercy Soong, Pranav Prabhala, Girija Goyal, Kenneth E Carlson, Ronald J Wong, Idit Kosti, Brian L Le, James Logue, Holly Hammond, Matthew Frieman, David K Stevenson, Donald E Ingber, Marina Sirota, Richard Novak
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1011050 (2023)
Drug repurposing requires distinguishing established drug class targets from novel molecule-specific mechanisms and rapidly derisking their therapeutic potential in a time-critical manner, particularly in a pandemic scenario. In response to the chall
Externí odkaz:
https://doaj.org/article/cfab81f7026e481d8f6ae5a6eade32cd
Autor:
Girija Goyal, Pranav Prabhala, Gautam Mahajan, Bruce Bausk, Tal Gilboa, Liangxia Xie, Yunhao Zhai, Roey Lazarovits, Adam Mansour, Min Sun Kim, Aditya Patil, Danielle Curran, Jaclyn M. Long, Sanjay Sharma, Abidemi Junaid, Limor Cohen, Thomas C. Ferrante, Oren Levy, Rachelle Prantil‐Baun, David R. Walt, Donald E. Ingber
Publikováno v:
Advanced Science, Vol 9, Iss 14, Pp n/a-n/a (2022)
Abstract Lymphoid follicles (LFs) are responsible for generation of adaptive immune responses in secondary lymphoid organs and form ectopically during chronic inflammation. A human model of ectopic LF formation will provide a tool to understand LF de
Externí odkaz:
https://doaj.org/article/72989818cd824b03a101649325a3d3a1
Autor:
Amir Bein, Seongmin Kim, Girija Goyal, Wuji Cao, Cicely Fadel, Arash Naziripour, Sanjay Sharma, Ben Swenor, Nina LoGrande, Atiq Nurani, Vincent N. Miao, Andrew W. Navia, Carly G. K. Ziegler, José Ordovas Montañes, Pranav Prabhala, Min Sun Kim, Rachelle Prantil-Baun, Melissa Rodas, Amanda Jiang, Lucy O’Sullivan, Gladness Tillya, Alex K. Shalek, Donald E. Ingber
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Many patients infected with coronaviruses, such as SARS-CoV-2 and NL63 that use ACE2 receptors to infect cells, exhibit gastrointestinal symptoms and viral proteins are found in the human gastrointestinal tract, yet little is known about the inflamma
Externí odkaz:
https://doaj.org/article/04fbdd996249478793a88fb6fec6e0fb
Autor:
James Logue, Arup R. Chakraborty, Robert Johnson, Girija Goyal, Louis J. Taylor, Lauren Baracco, Marisa E. McGrath, Robert Haupt, Melissa Rodas, Brooke A. Furlong, Mercy Soong, Pranav Prabhala, Viktor Horvath, Kenneth E. Carlson, Stuart Weston, Donald E. Ingber, Melvin L. DePamphilis, Matthew B. Frieman
The ongoing COVID-19 pandemic has claimed more than 6 million lives and continues to test the world economy and healthcare systems. To combat this pandemic, the biological research community has shifted efforts to the development of medical counterme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66c0b407f9cfce5cffaed88bdf9aece6
https://doi.org/10.21203/rs.3.rs-1605065/v1
https://doi.org/10.21203/rs.3.rs-1605065/v1
Autor:
Megan M. Sperry, Tomiko Oskotsky, Ivana Marić, Shruti Kaushal, Takako Takeda, Viktor Horvath, Rani K. Powers, Melissa Rodas, Brooke Furlong, Mercy Soong, Pranav Prabhala, Girija Goyal, Kenneth E. Carlson, Ronald J. Wong, Idit Kosti, Brian L. Le, James Logue, Holly Hammond, Matthew Frieman, David K. Stevenson, Donald E. Ingber, Marina Sirota, Richard Novak
Publikováno v:
medRxiv
PLoS computational biology, vol 19, iss 5
PLoS computational biology, vol 19, iss 5
SummaryImportanceDrug repurposing requires distinguishing established drug class targets from novel molecule-specific mechanisms and rapidly derisking their therapeutic potential in a time-critical manner, particularly in a pandemic scenario. In resp
Autor:
Yunhao Zhai, Girija Goyal, Pranav Prabhala, Aditya Patil, Min Sun Kim, Abidemi Junaid, Min Wen Ku, Gautam Mahajan, Bruce Bausk, Tal Gilboa, Roey Lazarovits, Sanjay Sharma, Limor Cohen, Thomas Ferrante, David R Walt, Donald E Ingber
Publikováno v:
The Journal of Immunology. 208:116.01-116.01
New vaccine candidates evaluated in animals can lead to unpredicted toxicities or poor efficacy in human clinical trials due to species-specific differences in immune responses. To address this problem, we developed the human ectopic lymphoid follicl
Autor:
Sanjay Sharma, Tal Gilboa, J. M. Long, Min Sun Kim, Gautam Mahajan, Rachelle Prantil-Baun, Girija Goyal, Pranav Prabhala, A. Mansour, Limor Cohen, L. Xie, Donald E. Ingber, Roey Lazarovits, Bruce Bausk, Oren Levy, David R. Walt, D. Curran, Y. Zhai
Lymphoid follicles (LFs) are responsible for generation of adaptive immune responses in secondary lymphoid organs and form ectopically during chronic inflammation. A human model of LF formation would provide a tool to understand LF development and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39681f7273628055b852f800b8e78c62
https://doi.org/10.1101/806505
https://doi.org/10.1101/806505