Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pranav Mathkar"'
Autor:
Pranav Mathkar, Anton Wagner, Wensen Jiang, Juliane D. Glaeser, Ritchie Ho, Giselle Kaneda, Dmitriy Sheyn, Khosrowdad Salehi
Publikováno v:
iScience. 25:104504
SUMMARYThe origin, composition, distribution, and function of cells in the human intervertebral disc (IVD) has not been fully understood. Here, cell atlases of both human neonatal and adult IVDs have been generated and further assessed by gene ontolo
Autor:
Daniel Oheb, Pranav Mathkar, Robert H. Baloh, Kevin Taylor, Maria G. Banuelos, Lisa Watson, Ritchie Ho, Irina Khrebtukova, Mariko Kellogg, Olubankole Aladesuyi Arogundade, Michael J. Workman, Jacqueline G. O’Rourke, Valerie Montel, Clive N. Svendsen, Kathryn Wu, Steven Huang, Kevin J. Kim, John Ravits, Sandra Diaz-Garcia
Publikováno v:
Cell systems, vol 12, iss 2
Cell Syst
Cell Syst
Induced pluripotent stem cell- (iPSC) derived neural cultures from amyotrophic lateral sclerosis (ALS) patients can model disease phenotypes. However, heterogeneity arising from genetic and experimental variability limits their utility, impacting rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9d968e1bff5ee806f39c17f0d3a1dc
https://escholarship.org/uc/item/1s686483
https://escholarship.org/uc/item/1s686483
Autor:
Ritchie Ho, Mariko Kellogg, Kevin J. Kim, Daniel Oheb, Michael J. Workman, Valerie Montel, Maria G. Banuelos, Robert H. Baloh, Kevin Taylor, Sandra Diaz Garcia, Kathryn Wu, Irena Khrebtukova, Pranav Mathkar, Jacqueline G. O’Rourke, Clive N. Svendsen, Steven Huang, Lisa Watson, Olubankole Aladesuyi, John Ravits
SummaryInduced pluripotent stem cell (iPSC) derived neural cultures from amyotrophic lateral sclerosis (ALS) patients can reflect disease phenotypes targetable by treatments. However, widely used differentiation protocols produce mixtures of progenit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f9035c29956979d361b53c3aa805e6
https://doi.org/10.1101/2020.04.27.064584
https://doi.org/10.1101/2020.04.27.064584
Publikováno v:
Journal of Huntington's Disease
Background Huntington's disease (HD) is an inherited neurodegenerative disease and is characterized by atrophy of certain regions of the brain in a progressive manner. HD patients experience behavioral changes and uncontrolled movements which can be
Autor:
Catherine Bresee, Jie Tang, Yizhou Wang, Colton M Tom, Pranav Mathkar, Virginia B. Mattis, Shagun Mehta, David Rushton
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 1081-1096.e6 (2018)
Summary: Huntington’s disease (HD) is a neurodegenerative disease caused by an expanded CAG repeat in the Huntingtin (HTT) gene. Induced pluripotent stem cell (iPSC) models of HD provide an opportunity to study the mechanisms underlying disease pat