Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Pranav Danthi"'
Autor:
Reshma Raghava Kurup, Eimile K. Oakes, Pranathi Vadlamani, Obi Nwosu, Pranav Danthi, Heather A. Hundley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The RNA binding protein ADAR3 is expressed exclusively in the brain and reported to have elevated expression in tumors of patients suffering from glioblastoma compared to adjacent brain tissue. Yet, other studies have indicated that glioblas
Externí odkaz:
https://doaj.org/article/3a4015789ad5453d80b8ed6500a5fef5
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3 (2022)
Successful initiation of infection by many different viruses requires their uptake into the endosomal compartment. While some viruses exit this compartment early, others must reach the degradative, acidic environment of the late endosome. Mammalian o
Externí odkaz:
https://doaj.org/article/934be254d8db43919f1d4320c77b265a
Publikováno v:
Cells, Vol 11, Iss 11, p 1757 (2022)
Mammalian orthoreoviruses (ReoV) are non-enveloped viruses with segmented double-stranded RNA genomes. In humans, ReoV are generally considered non-pathogenic, although members of this family have been proven to cause mild gastroenteritis in young ch
Externí odkaz:
https://doaj.org/article/e29dd02cdb1a4fd396a6433808e62820
Publikováno v:
Viruses, Vol 13, Iss 2, p 153 (2021)
Mammalian orthoreovirus (reovirus), a dsRNA virus with a multilayered capsid, serves as a model system for studying the entry of similar viruses. The outermost layer of this capsid undergoes processing to generate a metastable intermediate. The metas
Externí odkaz:
https://doaj.org/article/00c320c88d2f4ff8a653ac79163973f5
Autor:
Andrew T. Abad, Pranav Danthi
Publikováno v:
Viruses, Vol 12, Iss 6, p 667 (2020)
Mammalian orthoreovirus (reovirus) is a dsRNA virus, which has long been used as a model system to study host–virus interactions. One of the earliest interactions during virus infection is the detection of the viral genomic material, and the conseq
Externí odkaz:
https://doaj.org/article/53df4668615b4ce29a4ac6363ef5c872
Autor:
Anthony Snyder, Pranav Danthi
Publikováno v:
Bio-Protocol, Vol 8, Iss 2 (2018)
Mammalian orthoreovirus (reovirus) utilizes pore forming peptides to penetrate host cell membranes. This step is essential for delivering its genome containing core particle during viral entry. This protocol describes an in vitro assay for measuring
Externí odkaz:
https://doaj.org/article/fd8207e451b64f6d9d908b5cfc6eed29
Autor:
Anthony Snyder, Pranav Danthi
Publikováno v:
Bio-Protocol, Vol 8, Iss 2 (2018)
The mammalian orthoreovirus (reovirus) outer capsid undergoes a series of conformational changes prior to or during viral entry. These transitions are necessary for delivering the genome-containing core across host cell membranes. This protocol descr
Externí odkaz:
https://doaj.org/article/c87638810ca74814838174cf63700d4d
Autor:
Angela K. Berger, Pranav Danthi
Publikováno v:
mBio, Vol 4, Iss 3 (2013)
ABSTRACT Virus-induced apoptosis is thought to be the primary mechanism of cell death following reovirus infection. Induction of cell death following reovirus infection is initiated by the incoming viral capsid proteins during cell entry and occurs v
Externí odkaz:
https://doaj.org/article/a795bc8e8d6c4619a839400693d8a70f
Autor:
Pranav Danthi, Andrea J Pruijssers, Angela K Berger, Geoffrey H Holm, Sandra S Zinkel, Terence S Dermody
Publikováno v:
PLoS Pathogens, Vol 6, p e1000980 (2010)
Reovirus infection leads to apoptosis in both cultured cells and the murine central nervous system (CNS). NF-kappaB-driven transcription of proapoptotic cellular genes is required for the effector phase of the apoptotic response. Although both extrin
Externí odkaz:
https://doaj.org/article/f14c2417fc3a4ca59aae9d41dca81321
Publikováno v:
PLoS Pathogens, Vol 4, Iss 12, p e1000248 (2008)
Apoptosis plays an important role in the pathogenesis of reovirus encephalitis. Reovirus outer-capsid protein mu1, which functions to penetrate host cell membranes during viral entry, is the primary regulator of apoptosis following reovirus infection
Externí odkaz:
https://doaj.org/article/02c920671777479bb792dcd2854133e2