Výsledky vyhledávání - "Pranab K. Gupta"

ChemInform Abstract: Design, Synthesis, and Studies on the Structure Activity Relationships of Certain Pyrrolo(2,3-d)pyrimidine Nucleosides and Structurally Related Analogs as Potential Antineoplastic and Antiviral Agents

Autor: Jeffrey S. Pudlo, T. Maruyama, Linda L. Wotring, Steven H. Krawczyk, M. R. Nassiri, Leroy B. Townsend, S. Vittori, Naveen K. Saxena, Steven R. Turk, John C. Drach, Eric E. Swayze, L. A. Coleman, Allison C. Westerman, Pranab K. Gupta, J. J. Spurr

Publikováno v: ChemInform. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c54cd31760a5b53748f2990bf92269b
https://doi.org/10.1002/chin.199134306

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Synthesis of β-D-ribo- and 2′-deoxy-β-D-ribofuranosyl derivatives of 6-aminopyrazolo[4,3-c]pyridin-4(5H)-one by a ring closure of pyrazole nucleoside precursors

Autor: N. Kent Dalley, G. R. Revankar, Pranab K. Gupta, Roland K. Robins

Publikováno v: Journal of Heterocyclic Chemistry. 23:59-64

6-Amino-1-(2-deoxy-β-D-erthro-pentofuranosyl)pyrazolo[4,3-c]pyridin-4(5H)-one (5), as well as 2-(β-D-ribofuranosyl)- and 2-(2-deoxy-β-D-ribofuranosyl)- derivatives of 6-aminopyrazolo[4,3-c]pyridin-4(5H)-one (18 and 22, respectively) have been synt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a32a71c5fb16bb9b12d0a009900fbd68
https://doi.org/10.1002/jhet.5570230112

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Synthesis, cytotoxicity, and antiviral activity of certain 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine nucleosides related to toyocamycin and sangivamycin

Autor: John C. Drach, M. Reza Nassiri, Linda L. Wotring, Leroy B. Townsend, L. A. Coleman, Pranab K. Gupta

Publikováno v: Journal of Medicinal Chemistry. 32:1420-1425

A number of 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine derivatives related to the nucleoside antibiotics toyocamycin and sangivamycin were prepared and tested for their biological activity. Treatment of the sodium salt of 4-amino-6-bromo-5-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7ee46f655797a9996d393a4ad8c5f3
https://doi.org/10.1021/jm00127a003

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Synthesis of certain exocyclic thiazole nucleosides related to tiazofurin. Formation of a unique acycloaminonucleoside

Autor: Pranab K. Gupta, Steven B. Larson, N. Kent Dalley, Roland K. Robins, Yogesh S. Sanghvi, Ganapathi R. Revankar, Rose D. George

Publikováno v: Journal of Heterocyclic Chemistry. 25:623-633

Several thiazole nucleosides structurally related to tiazofurin (1) and ARPP (2) were prepared, in order to determine whether these nucleosides had enhanced antitumor/antiviral activities. Ring closure of 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aba256b2b2fa6977e3a89d39da538819
https://doi.org/10.1002/jhet.5570250248

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A new synthesis of certain 7-(beta-D-ribofuranosyl) and 7-(2-deoxy-beta-D-ribofuranosyl) derivatives of 3-deazaguanine via the sodium salt glycosylation procedure

Autor: Ganapathi R. Revankar, Roland K. Robins, Pranab K. Gupta

A facile synthesis of 7-beta-D-ribofuranosyl-3-deazaguanine (1) and certain 8-substituted derivatives of 1 via the sodium salt glycosylation method has been developed. Glycosylation of the sodium salt of methyl 2-chloro(or methylthio)-4(5)-cyanomethy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d477f0392f73a7371c0e6185ca92cb0
https://europepmc.org/articles/PMC321869/

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ChemInform Abstract: Synthesis, Cytotoxicity, and Antiviral Activity of Certain 7-((2-Hydroxyethoxy)methyl)pyrrolo(2,3-d)pyrimidine Nucleosides Related to Toyocamycin and Sangivamycin

Autor: John C. Drach, L. A. Coleman, Leroy B. Townsend, Linda L. Wotring, M. R. Nassiri, Pranab K. Gupta

Publikováno v: ChemInform. 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8f0879266ba94524a88aa6332adcc4a
https://doi.org/10.1002/chin.198949297

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Synthesis, cytotoxicity, and antiviral activity of some acyclic analogues of the pyrrolo[2,3-d]pyrimidine nucleoside antibiotics tubercidin, toyocamycin, and sangivamycin

Autor: Leroy B. Townsend, John C. Drach, M. Reza Nassiri, Pranab K. Gupta, Sylvia Daunert, Linda L. Wotring

Publikováno v: Journal of medicinal chemistry. 32(2)

A number of 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3d-d]pyrimidine derivatives that are structurally related to toyocamycin and sangivamycin and the seco nucleosides of tubercidin, toyocamycin, and sangivamycin were prepared and tested for thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5417b9789c0fea87106a8104dcd592b1
https://pubmed.ncbi.nlm.nih.gov/2913300

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