Výsledky vyhledávání - "Pranab K Mukherjee"

Akademický článek

Blocking pro-inflammatory platelet-activating factor receptors and activating cell survival pathways: A novel therapeutic strategy in experimental ischemic stroke

Autor: Ludmila Belayev, Andre Obenaus, Pranab K Mukherjee, Eric J Knott, Larissa Khoutorova, Madigan M Reid, Cassia R Roque, Lawrence Nguyen, Jeong Bin Lee, Nicos A Petasis, Reinaldo B Oria, Nicolas G Bazan

Publikováno v: Brain Circulation, Vol 6, Iss 4, Pp 260-268 (2020)

OBJECTIVE: Acute ischemic stroke triggers complex neurovascular, neuroinflammatory, and synaptic alterations. This study explores whether blocking pro-inflammatory platelet-activating factor receptor (PAF-R) plus selected docosanoids after middle cer

Externí odkaz: https://doaj.org/article/6289569029d44cd3a5d5b4edf56b4704

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Akademický článek

Dysbiosis in the oral bacterial and fungal microbiome of HIV-infected subjects is associated with clinical and immunologic variables of HIV infection.

Autor: Pranab K Mukherjee, Jyotsna Chandra, Mauricio Retuerto, Curtis Tatsuoka, Mahmoud A Ghannoum, Grace A McComsey

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0200285 (2018)

BACKGROUND:The effect of smoking on microbial dysbiosis and the potential consequence of such shift on markers of HIV disease is unknown. Here we assessed the relationship of microbial dysbiosis with smoking and markers of HIV disease. METHODS:Oral w

Externí odkaz: https://doaj.org/article/28012fa200624eaead08c6d8324bdb76

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Akademický článek

Quorum-sensing dysbiotic shifts in the HIV-infected oral metabiome.

Autor: Robert E Brown, Mahmoud A Ghannoum, Pranab K Mukherjee, Patrick M Gillevet, Masoumeh Sikaroodi

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0123880 (2015)

We implemented a Systems Biology approach using Correlation Difference Probability Network (CDPN) analysis to provide insights into the statistically significant functional differences between HIV-infected patients and uninfected individuals. The ana

Externí odkaz: https://doaj.org/article/b02cc16e05794f8888ee0ecb3d899e37

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Akademický článek

Oral mycobiome analysis of HIV-infected patients: identification of Pichia as an antagonist of opportunistic fungi.

Autor: Pranab K Mukherjee, Jyotsna Chandra, Mauricio Retuerto, Masoumeh Sikaroodi, Robert E Brown, Richard Jurevic, Robert A Salata, Michael M Lederman, Patrick M Gillevet, Mahmoud A Ghannoum

Publikováno v: PLoS Pathogens, Vol 10, Iss 3, p e1003996 (2014)

Oral microbiota contribute to health and disease, and their disruption may influence the course of oral diseases. Here, we used pyrosequencing to characterize the oral bacteriome and mycobiome of 12 HIV-infected patients and matched 12 uninfected con

Externí odkaz: https://doaj.org/article/f7d6d9306ece40f9b7c1124be690ffba

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Akademický článek

Elovanoid-N34 modulates TXNRD1 key in protection against oxidative stress-related diseases

Autor: Jorgelina M. Calandria, Surjyadipta Bhattacharjee, Sayantani Kala-Bhattacharjee, Pranab K. Mukherjee, Yuehan Feng, Jakob Vowinckel, Tobias Treiber, Nicolas G. Bazan

Publikováno v: Cell Death and Disease, Vol 14, Iss 12, Pp 1-10 (2023)

Abstract The thioredoxin (TXN) system is an NADPH + H+/FAD redox-triggered effector that sustains homeostasis, bioenergetics, detoxifying drug networks, and cell survival in oxidative stress-related diseases. Elovanoid (ELV)-N34 is an endogenously fo

Externí odkaz: https://doaj.org/article/dbebac66dc1540809737569171643c4e

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Akademický článek

Characterization of the oral fungal microbiome (mycobiome) in healthy individuals.

Autor: Mahmoud A Ghannoum, Richard J Jurevic, Pranab K Mukherjee, Fan Cui, Masoumeh Sikaroodi, Ammar Naqvi, Patrick M Gillevet

Publikováno v: PLoS Pathogens, Vol 6, Iss 1, p e1000713 (2010)

The oral microbiome-organisms residing in the oral cavity and their collective genome-are critical components of health and disease. The fungal component of the oral microbiota has not been characterized. In this study, we used a novel multitag pyros

Externí odkaz: https://doaj.org/article/d1a76907d5a042ee958f94913aafd8c6

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Akademický článek

Single-cell isolation from full-thickness human intestinal tissue resections for single-cell RNA sequencing

Autor: Gail A. West, Shuai Zhao, Quang Tam Nguyen, Stephen M. Christensen, Ilyssa O. Gordon, Stefan D. Holubar, Kellie M. Kravarik, Claudio Fiocchi, Pranab K. Mukherjee, Florian Rieder

Publikováno v: STAR Protocols, Vol 4, Iss 4, Pp 102686- (2023)

Summary: Single-cell isolation techniques allow the investigation of physical and functional relationships between individual cells within a complex cell population. Here, we present a protocol for single-cell isolation from full-thickness intestinal

Externí odkaz: https://doaj.org/article/d6d3a645def64a3bac390c7b218bc539

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