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Abstract 2295: SGK2, 14-3-3, and HUWE1 coordinately regulate the localization and stability of PTOV1
Autor:
Colten M. McEwan, Pramoda S. Aththota Gamage, Crissy M. Egbert, Riley J. Eastmond, James Woods, Stephen R. Piccolo, Joshua L. Andersen, Colin Muir, Katie L. Pennington, Tyler Heaton
Publikováno v:
Cancer Research. 81:2295-2295
PTOV1 is an oncogenic protein, initially identified in prostate cancer, that promotes proliferation, cell motility, and invasiveness. However, the mechanism of PTOV1 regulation is poorly understood. To understand these mechanisms, we identify 14-3-3