Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Pramod S. Salve"'
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Background The current investigation aimed to develop, optimise, and assess a mupirocin-loaded nanosponge-based topical delivery system for diabetic foot ulcer and to achieve prolonged drug release while improving drug deposition within the
Externí odkaz:
https://doaj.org/article/10ca28fdf0f74435a9993746f10dc4ae
Autor:
Pramod S. Salve, Nikhil Bali
Publikováno v:
International Journal of Biological Macromolecules. 164:1006-1024
Rasagiline mesylate is used as first line agent for early management of Parkinson's disease but its water soluble nature creates hurdles to cross blood brain barrier also its low oral bioavailability and rapid elimination requires frequent dosing. Th
Publikováno v:
International Journal of Polymeric Materials and Polymeric Biomaterials. 70:158-173
Rasagiline mesylate (RM) used as first-line agent for Parkinsonism exhibit low oral-bioavailability and extensive hepatic first-pass metabolism requires frequent administration. Polymeric nanoparti...
Autor:
Pramod S. Salve, Shahadev B. Rathod
Publikováno v:
Journal of Drug Delivery and Therapeutics. 9:505-518
Venlafaxine hydrochloride (VH) is a serotonin-noradrenaline reuptake inhibitor indicated for treatment of depression disorder. It shows low biological half-life 5±2 h and low oral bioavailability 45±15 % due to extensive hepatic first-pass metaboli
Autor:
Nikhil Bali, Pramod S. Salve
Publikováno v:
Journal of Drug Delivery and Therapeutics. 9:344-351
Purpose: Selegiline HCl (SGN) is indicated for treatment of Parkinson’s disease (PD). Its mode of action involves inhibition of MAO-B enzyme. It shows extensive hepatic first-pass metabolism and low biological half-life of 1.2 -2 hours. It results
Publikováno v:
Drug development and industrial pharmacy. 46(5)
Objective: Agomelatine (AGM), an antidepressant drug has low biological half-life coupled with extensive hepatic first-pass metabolism. For effective treatment of depression, daily medication is re...
Autor:
Nikhil Bali, Pramod S. Salve
Publikováno v:
Journal of Drug Delivery Science and Technology. 54:101299
Present study was aimed to design and optimize ethylene vinyl acetate transdermal films containing selegiline-loaded poly (lactic-co-glycolic acid) nanoparticles for effective brain targeting along with its in-vitro and in-vivo evaluation. Transderma
Publikováno v:
Asian Journal of Pharmacy and Technology. 6:61
Coronary artery diseases (CAD) represent a condition in which the blood supply to the heart muscle is partially or completely blocked. In atherosclerosis, the hardening of arteries occurs with decreasing elasticity of the arteries. For management of
Publikováno v:
Research Journal of Pharmaceutical Dosage Forms and Technology. 8:73
Solid lipid nanoparticles (SLN) loaded formulation as an alternative to oral and parenteral delivery of rivastigmine tartarate (RT), a water-soluble drug by using Precirol ATO 5 and tween 80. The SLN prepared by hot high pressure homogenization metho
Publikováno v:
Research Journal of Pharmacy and Technology. 9:741
Waxes retards drug release from dosage form based on their lipophilic characteristics. In this study, the effect of hot melt spray coated Verapamil pellets with composition of stearic acid, carnauba wax; glyceryl monostearate and polyethylene glycol