Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Pramod M. Lad"'
Autor:
Rebecca Dahl, Pramod M. Lad
Publikováno v:
Accountability in research. 22(3)
Clinical research studies in children are classified by risk into three major categories. These are as follows: a) minimal risk studies, b) more than minimal risk studies but with benefit, and c) studies with minor increase over minimal risk but with
Autor:
Rebecca Dahl, Pramod M. Lad
Publikováno v:
Accountability in research. 21(5)
Language barriers in the informed consent process can be a significant impediment when recruiting non-English speaking subjects into clinical research studies. Regulatory guidelines indicate that the short form procedure be utilized in such circumsta
Publikováno v:
The Journal of Urology. :2284-2288
To evaluate the possible role of cytokines interleukin (IL)-1beta, IL-1alpha and IL-6 in patients with urolithiasis.Fifty-six patients currently with stone disease, 63 patients with bacterial cystitis, and 66 normal individuals were evaluated for uri
Autor:
Rebecca Dahl, Pramod M. Lad
Publikováno v:
Science and engineering ethics. 20(2)
Audits of the informed consent process are a key element of a clinical research quality assurance program. A systematic approach to such audits has not been described in the literature. In this paper we describe two components of the audit. The first
Autor:
Fun-Shan Chen, Tam Thuan Nguyen, C. Linzhi Wang, Pramod M. Lad, John S. Kaptein, Cosmas I. Kalunta, Eunhee Park, Ching-Kow E. Lin
Publikováno v:
Journal of Biological Chemistry. 271:18875-18884
Anti-IgM treatment of Burkitt's lymphoma cells is followed by either growth arrest or induction of apoptosis. In this study we have explored the role of c-myc in these events. Our results in Ramos cells indicate the following. (a) The decline in c-my
Autor:
Scott K. Yun, Pramod M. Lad, Lisa Stout, Jill M. Gerspach, Gary E. Leach, Susan M. Levy, Philippe E. Zimmern
Publikováno v:
Urology. 46:653-656
Objectives Dimethyl sulfoxide (DMSO), an agent that provides symptomatic relief in patients with interstitial cystitis (IC) works via an unknown mechanism. We investigated whether DMSO acts as a chemical stimulant of mast cell degranulation. Methods
Autor:
C. Linzhi Yang, John S. Kaptein, Tam Thuan Nguyen, Ching-Kow E. Lin, Fun-Shan Chen, Pramod M. Lad
Publikováno v:
Immunobiology. 193:465-485
Expression of the protooncogene c-fos is controlled by three main regulatory pathways involving kinase C, cAMP, and calcium. Kinase C mediates its effects via phosphorylation of serum response factor (SRF) which interacts with the serum response elem
Autor:
Ching-Kow E. Lin, John S. Kaptein, Fun-Shan Chen, Cosmas I. Kalunta, Pramod M. Lad, Cindy F. Yen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1257:47-57
The status of low-density lipoprotein receptors (LDLR) in Daudi Burkitt's lymphoma (BL) cells was examined using a flow cytometric assay employing the fluorescent ligand DiI-LDL, and a radioligand-binding assay using [ 125 I]LDL. The binding is conce
Autor:
Tam Thuan Nguyen, Ching-Kow E. Lin, Cosmas I. Kalunta, Pramod M. Lad, Fun-Shan Chen, John S. Kaptein
Publikováno v:
Experimental Cell Research. 216:403-410
Previous reports have suggested that dimethyl sulfoxide (DMSO) may be a useful reversible G1 arresting agent for synchronizing Raji Burkitt's lymphoma cells (K. Takase et al. (1992) Cell Growth Differ. 3, 515-521; M. Sawai et al. (1990) Exp. Cell Res
Publikováno v:
Journal of Urology. 151:1198-1201
Urinary cytokines as markers for the intravesical inflammatory response have become an active area of research. Interleukin-1b, a well studied and early produced cytokine in the immune recognition cascade, was evaluated. After extensive analysis of 5