Zobrazeno 1 - 10
of 322
pro vyhledávání: '"Pramod K Srivastava"'
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6094 (2009)
DNA replication has a finite measurable error rate, net of repair, in all cells. Clonal proliferation of cancer cells leads therefore to accumulation of random mutations. A proportion of these mutational events can create new immunogenic epitopes tha
Externí odkaz:
https://doaj.org/article/9f0727d07b7e4a038fe2bd90b52f43b1
Autor:
Youhui Si, Yihan Wang, Qiaomu Tian, Qiang Wang, Jared M. Pollard, Pramod K. Srivastava, Aaron P. Esser-Kahn, Joel H. Collier, Anne I. Sperling, Anita S. Chong
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113299- (2023)
Summary: The current paradigm indicates that naive T cells are primed in secondary lymphoid organs. Here, we present evidence that intranasal administration of peptide antigens appended to nanofibers primes naive CD8+ T cells in the lung independentl
Externí odkaz:
https://doaj.org/article/48a2691e5f364f34ac914d99f2c04e72
Autor:
Hakimeh Ebrahimi-Nik, Marmar Moussa, Ryan P. Englander, Summit Singhaviranon, Justine Michaux, HuiSong Pak, Hiroko Miyadera, William L. Corwin, Grant L. J. Keller, Adam T. Hagymasi, Tatiana V. Shcheglova, George Coukos, Brian M. Baker, Ion I. Mandoiu, Michal Bassani-Sternberg, Pramod K. Srivastava
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The immunogenicity of peptides is believed to be determined by their high-affinity binding to MHC I. Here authors show that low-affinity MHC I-peptide interactions are also able to trigger robust T cell response and anti-tumour immunity in vivo.
Externí odkaz:
https://doaj.org/article/1e4f015d0d0f4721934a300013d3a61f
Autor:
Sahar Al Seesi, Anas Al-okaily, Tatiana V. Shcheglova, Elham Sherafat, Fahad H. Alqahtani, Adam T. Hagymasi, Anupinder Kaur, Pramod K. Srivastava, Ion I. Măndoiu
Publikováno v:
Journal of Computational Biology. 30:538-551
Autor:
Pramod K. Srivastava, Kamal M. Khanna, Shashmita Pattnayak, Alexandre P. Bénéchet, Isaac Tirrell, Alok Das Mohapatra
Live cells are the most abundant sources of antigen in a tumor-bearing host. Here, we used live tumor cells as source of antigens to investigate the mechanism underlying their immunogenicity in murine tumor models. The live tumor cells were significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488eecac42eb94c84a9e812b2dfbc8df
https://doi.org/10.1158/2326-6066.c.6550065.v1
https://doi.org/10.1158/2326-6066.c.6550065.v1
Autor:
Pramod K. Srivastava, Kamal M. Khanna, Shashmita Pattnayak, Alexandre P. Bénéchet, Isaac Tirrell, Alok Das Mohapatra
Supplementary Figures 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15568284f3f2791feda02863131c8dab
https://doi.org/10.1158/2326-6066.22542870.v1
https://doi.org/10.1158/2326-6066.22542870.v1
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f68f195247d892d467978101ae1ebf2c
https://doi.org/10.1007/978-1-0716-2938-3_18
https://doi.org/10.1007/978-1-0716-2938-3_18
Publikováno v:
Current Protocols. 2
Heat-shock proteins (HSPs), or stress proteins, are abundant and highly conserved, present in all organisms and in all cells. Selected HSPs, also known as chaperones, play crucial roles in folding and unfolding of proteins, assembly of multiprotein c
Publikováno v:
Cancer Research. 83:608-608
The frequency of CD8+ tumor infiltrating lymphocytes (TILs) has been positively associated with overall survival in several cancers. The interaction of T cell receptors (TCRs) on T cells with Major Histocompatibility Complex (MHC)-peptide complexes o