Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Pramod Dhakal"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9693 (2021)
In this study, we investigated the effects of ablation of uterine Forkhead Box A2 (Foxa2) on gene expression of fetal brain relative to placenta. Using a conditional knockout mouse model for uterine Foxa2, here we show that the lack of uterine Foxa2
Externí odkaz:
https://doaj.org/article/ed376ee8550e4bc59384b380988c8ef3
Autor:
Pramod Dhakal, Michael J. Soares
Publikováno v:
BioTechniques, Vol 62, Iss 5, Pp 232-233 (2017)
The advent of genome editing strategies has expanded the range of animal models available for gene manipulation and renewed research interest in the rat. Gender is a key variable for in vivo gene function analyses. Here, we present a simple PCR-based
Externí odkaz:
https://doaj.org/article/91057f864e02430fb053337a04203e8d
Autor:
Marija Kuna, Pramod Dhakal, Khursheed Iqbal, Esteban M. Dominguez, Lindsey N. Kent, Masanaga Muto, Ayelen Moreno-Irusta, Keisuke Kozai, Kaela M. Varberg, Hiroaki Okae, Takahiro Arima, Henry M. Sucov, Michael J. Soares
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Establishment of the hemochorial uterine–placental interface requires exodus of trophoblast cells from the placenta and their transformative actions on the uterus, which represent processes critical for a successful pregnancy, but are poorly unders
Publikováno v:
Placenta. 112:123-131
Introduction The development of fetal brain is intricately dependent upon placental functions. Recently, we showed that the placenta and fetal brain express genes in a coordinated manner in mice. But, how the brain-placental axis is regulated at the
Autor:
Kazuyoshi Taya, Kentaro Nagaoka, Yasuo Nambo, Nobuo Tsunoda, Hiroyuki Taniyama, Pramod Dhakal, Gen Watanabe
Publikováno v:
Journal of Equine Science
Although equine gestation is unique from the standpoint of fetal gonadal enlargement and regression, the activator of this process is still unknown. The present study aimed to show a possible role of activin during equine gestation. In the first expe
Autor:
Marija Kuna, Pramod Dhakal, Khursheed Iqbal, Esteban M. Dominguez, Lindsey N. Kent, Masanaga Muto, Ayelen Moreno-Irusta, Keisuke Kozai, Kaela M. Varberg, Hiroaki Okae, Takahiro Arima, Henry M. Sucov, Michael J. Soares
Establishment of the hemochorial uterine-placental interface requires exodus of trophoblast cells from the placenta and their transformative actions on the uterus, which represent processes critical for a successful pregnancy, but are poorly understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6505b1df5f699c83fa6ce13b35aef78
https://doi.org/10.1101/2022.06.15.496287
https://doi.org/10.1101/2022.06.15.496287
Publikováno v:
Reprod Sci
Catechol-O-methyltransferase (COMT) has been shown to be a key regulator of pregnancy outcomes in mouse, and its deficiency is causative in the development of a preeclampsia-like disease process. Preeclampsia is a human pregnancy disorder associated
Publikováno v:
Proc Natl Acad Sci U S A
Glands of the uterus are essential for pregnancy establishment. Forkhead box A2 (FOXA2) is expressed specifically in the glands of the uterus and a critical regulator of glandular epithelium (GE) differentiation, development, and function. Mice with
Autor:
Pramod Dhakal, Sanjaya Dhungana, Nirmala Jamarkattel-Pandit, Sujan Baral, Kishor Adhikari, Laxman Wagle
Publikováno v:
Journal of Health and Allied Sciences. 5:34-38
Alopecia is common and most frequently complaint dermatological disorder since the time immemorial. Various herbal and allopathic formulations are reported to have hair growth promoting activity. Minoxidil and Finasteride are only US FDA approved dru
Autor:
Stephen H. Pierce, Pramod Dhakal, Carrie A. Vyhlidal, Katherine F. Roby, Khursheed Iqbal, Michael J. Soares, Regan L. Scott, Keisuke Kozai
Publikováno v:
Environmental Health Perspectives
Background Our environment is replete with chemicals that can affect embryonic and extraembryonic development. Dioxins, such as 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD), are compounds affecting development through the aryl hydrocarbon receptor (A