Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Pramod A. Pullarkat"'
Autor:
Renu Vishavkarma, Swetavalli Raghavan, Chandrashekar Kuyyamudi, Abhijit Majumder, Jyotsna Dhawan, Pramod A Pullarkat
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107895 (2014)
It is well known that substrate properties like stiffness and adhesivity influence stem cell morphology and differentiation. Recent experiments show that cell morphology influences nuclear geometry and hence gene expression profile. The mechanism by
Externí odkaz:
https://doaj.org/article/bc0078c3306849398ec99ad924806599
Rheological properties of a material often require to be probed under extensional deformation. Examples include fibrous materials such as spider-silk, high-molecular weight polymer melts, and the contractile response of living cells. Such materials h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1376ecffaec52a08d954bdf0075bf25d
http://arxiv.org/abs/2006.15958
http://arxiv.org/abs/2006.15958
Autor:
Sukh Veer, Aurnab Ghose, Nishita Bhembre, Andrew Callan-Jones, Shivani Bodas, Sushil Dubey, Pramod A. Pullarkat
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Axons span extreme distances and are subject to significant stretch deformations during limb movements or sudden head movements, especially during impacts. Yet, axon biomechanics, and its relation to the ultrastructure that allows axons to withstand
Publikováno v:
Biophysical Journal. 115:713-724
Mechanotransduction is likely to be an important mechanism of signalling in thin, elongated cells like neurons. Maintenance of pre-stress or rest tension may facilitate mechanotransduction in these cells. In recent years, functional roles for mechani
Autor:
Sukh Veer, Sushil Dubey, Divya Uma, Sayantan Majumdar, Hema Somanathan, Pramod A. Pullarkat, Chinmay Hemant Joshi
Spider silk possesses unique mechanical properties like large extensibility, high tensile strength, super-contractility, etc. Understanding these mechanical responses require characterization of the rheological properties of silk beyond the simple fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faad95d520305320875dd10ee623785f
http://arxiv.org/abs/1908.01595
http://arxiv.org/abs/1908.01595
Autor:
Jaishabanu Ameeramja, Anagha Datar, Andrew Callan-Jones, Pramod A. Pullarkat, Ashish Kumar Mishra, Jacques Prost, Roli Srivastava, Roberto Bernal, Alka Bhat
Publikováno v:
Biophys J
Biophysical Journal
Biophysical Journal, Biophysical Society, 2019, 117, pp.880-891. ⟨10.1016/j.bpj.2019.07.046⟩
Biophysical Journal
Biophysical Journal, Biophysical Society, 2019, 117, pp.880-891. ⟨10.1016/j.bpj.2019.07.046⟩
Axonal beading—formation of a series of swellings along the axon—and retraction are commonly observed shape transformations that precede axonal atrophy in Alzheimer’s, Parkinson, and other neurodegenerative conditions. The mechanisms driving th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac9c3e2deef63d6bfef4f9850209c2e
Autor:
Nishita Bhembre, Shivani Bodas, Sushil Dubey, Aurnab Ghose, Pramod A. Pullarkat, Andrew Callan-Jones
Axons are thin tubular extensions generated by neuronal cells to transmit signals across long distances. In the peripheral and the central nervous systems, axons experience large deformations during normal activity or as a result of injury. Yet, axon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2eaeab6a306da2f87b424007437d11
https://doi.org/10.1101/510560
https://doi.org/10.1101/510560
Publikováno v:
Biophysical Journal. 118:604a
Publikováno v:
Physical biology. 15(4)
Changes in cell-substrate adhesion are believed to signal the onset of cancer metastasis, but such changes must be quantified against background levels of intrinsic heterogeneity between cells. Variations in cell-substrate adhesion strengths can be p