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pro vyhledávání: '"Pramila Rayudu"'
Autor:
Zaki Munshi, Dibyendu Mondal, Velavan Armugam, Frank M. Dautzenberg, Claude Ostermann, Amit Bhalerao, Vinod Gudaghe, Guido Hanauer, Nisha Pansare, Koushik Das Sarma, Mahendra Gupta, Klaus Mann, Pramila Rayudu, Michaela Schaefer, Sandra Nappe, Afsar Ali Siddiki, Cornelia Weiss-Haljiti, Christof Zitt, Hans-Peter Kley, Yithachu Thur
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:7314-7321
SAR studies were performed on a series of 2-arylamido-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide derivatives as cannabinoid receptor agonists. Starting from a HTS hit both potency and selectivity could be improved. Modifications to the thiophene