Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pramathesh S. Patel"'
Autor:
L. Dean, Dolores M. Pirnik, Carol Ann Aklonis, Pramathesh S. Patel, Friedrich Mayerl, Prabhavathi B. Fernandes, Stella Huang, Edward Meyers, Susan M. Fisher
Publikováno v:
The Journal of Antibiotics. 48:997-1003
Bacillaene, a novel polyene antibiotic, was discovered and isolated from fermentation broths of a strain of Bacillus subtilis. The novel antibiotic has a nominal molecular weight of 580 and an empirical formula of C35H48O7. Bacillaene is active again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c71416673aa3bbc2f0a18869090a4f
https://doi.org/10.7164/antibiotics.48.997
https://doi.org/10.7164/antibiotics.48.997
Autor:
David A. Lach, Pramathesh S. Patel, Bernadette Kienzle, Patricia M. Rose, Jiri Novotny, Susan M. Fisher, Maria L. Webb, Jean S. Lynch, Stanley R. Krystek, Eddie C.-K. Liu
Publikováno v:
Journal of Biological Chemistry. 269:12383-12386
The molecular basis for endothelin (ET) isopeptide selectivity between ETA and ETB receptors was studied by examining ligand binding to several site-specific mutants of the human ETA receptor. Based on a computer-built three-dimensional model of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398cd76b09274afa15effd5b20240b86
https://doi.org/10.1016/s0021-9258(18)99881-9
https://doi.org/10.1016/s0021-9258(18)99881-9
Autor:
Dolores M. Pirnik, Steven E. Klohr, J S Wells, Kevin J. Volk, Richard R. Wang, Pramathesh S. Patel, Prabhavathi B. Fernandes, Yue-Zhong Shu, Stella Huang, Kin Sing Lam
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d0eb613a6d4dfb7b5045e2da9957f32
https://doi.org/10.1002/chin.199435286
https://doi.org/10.1002/chin.199435286
Autor:
Kyung O. Johanson, Jim A. Fornwald, Amy Calamari, Joyce Mao, Dwight D Moore, Kristin A. Knecht, Allan R. Shatzman, Stephen H. Trulli, Peter M. Tapley, Rosalie Matico, Robert B. Kirkpatrick, Louis Elefante, John J. Trill, Silas Nwagwu, Pramathesh S Patel, James F. Kane, Patrick McDevitt, Megan M. McLaughlin, Ganesh M. Sathe, Zdenka Ludmila Jonak, Adam F Yorke
Publikováno v:
Protein expression and purification. 27(2)
Interleukin-18 (IL-18) is activated and released from immune effector cells to stimulate acquired and innate immune responses involving T and natural killer (NK) cells. The release of IL-18 from mammalian cells is linked to its proteolytic activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018a001c8b616e61b514df670146881a
https://pubmed.ncbi.nlm.nih.gov/12597888
https://pubmed.ncbi.nlm.nih.gov/12597888
Autor:
Susan M. Fisher, Patricia M. Rose, S. Skwish, Kenneth E.J. Dickinson, Helen Lee, Pramathesh S. Patel, Philip D. Stein, Terry R. Stouch, Maria L. Webb, David A. Lach, Joel C. Barrish, Stanley R. Krystek, Ophelia W. Hadjilambris, Eddie C.-K. Liu
Publikováno v:
Biochemistry. 35(8)
Endothelin (ET) receptor antagonism is a potential therapeutic intervention in the treatment of vascular diseases. To elucidate the mechanism of antagonist-ET receptor complex formation, the interactions of four chemically distinct antagonists were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::591adcf8cecccedf1325bd2e46f103f2
https://pubmed.ncbi.nlm.nih.gov/8611558
https://pubmed.ncbi.nlm.nih.gov/8611558
Autor:
Jean S. Lynch, Stanley R. Krystek, Maria L. Webb, Eddie C.-K. Liu, Patricia M. Rose, Susan M. Fisher, Pramathesh S. Patel, David A. Lach
Publikováno v:
FEBS letters. 361(2-3)
The endothelin receptors, ET A and ET B , are G protein-coupled receptors (GPCR) that show distinctively different binding profiles for the endothelin peptides and other ligands. We recently reported that Tyr 129 in the second transmembrane region (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470cdeaad67fd3cfbd4fe3c97c46aa4c
https://pubmed.ncbi.nlm.nih.gov/7698331
https://pubmed.ncbi.nlm.nih.gov/7698331
Autor:
Kevin J. Volk, Steven E. Klohr, Yue-Zhong Shu, Richard R. Wang, Pramathesh S. Patel, Prabhavathi B. Fernandes, Stella Huang, Kin Sing Lam, Dolores M. Pirnik, J. C. Wells
Publikováno v:
The Journal of antibiotics. 47(3)
Three new manumycin class antibiotics, namely manumycins E, F and G, were isolated from the culture broth of Streptomyces sp. strain WB-8376. Their structures were established by spectroscopic methods, and the S configuration of C-4 in the epoxycyclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8f76c1fcf86380e55209534803bcba
https://pubmed.ncbi.nlm.nih.gov/8175485
https://pubmed.ncbi.nlm.nih.gov/8175485