Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pralhad Namdev Joshi"'
Autor:
Neelesh C. Reddy, Rajib Molla, Pralhad Namdev Joshi, Sajeev T. K., Ipsita Basu, Jyotsna Kawadkar, Neetu Kalra, Ram Kumar Mishra, Suman Chakrabarty, Sanjeev Shukla, Vishal Rai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Controlling the selectivity of the chemical modification of a genetic-manipulation-free protein is currently problematic. Here the authors report a method using cysteine-based chemoselective Linchpin Directed site-selective Modification of the lysine
Externí odkaz:
https://doaj.org/article/06df9bfd5b40499cacef9975977e5b0c
Autor:
Evgeniy Mervinetsky, Assaf Friedler, Yu-Ju Chen, Shlomo Yitzchaik, Ohad Solomon, Pralhad Namdev Joshi
Publikováno v:
Biosensorsbioelectronics. 207
Kinases are important cancer biomarkers and are conventionally detected based on their catalytic activity. Kinases regulate cellular activities by phosphorylation of motif-specific multiple substrate proteins, resulting in a lack of selectivity of ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a579ab443d5861f71ba1fc834e04c1ec
https://pubmed.ncbi.nlm.nih.gov/35305389
https://pubmed.ncbi.nlm.nih.gov/35305389
Autor:
Pralhad Namdev Joshi, Vishal Rai
Publikováno v:
Chemical Communications. 55:1100-1103
A precision methodology distinguishes one His from all the nucleophilic residues and its multiple copies. An easy-to-operate C-N bond formation labels diverse proteins without adversely affecting their structure and function. The late-stage transform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70443445b9972674c3b33809a5f409c
https://doi.org/10.1039/c8cc08733d
https://doi.org/10.1039/c8cc08733d
Publikováno v:
RSC Advances. 6:208-211
Self-assembled states of proteins render efficient promiscuous nucleophilic biocatalysis in MBH reaction in a green process. The His and Arg based catalophores in proteins operate in aqueous buffer at neutral pH and ambient temperature. Steady-state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15aebc8ff726cc2e184783db9b3ebacb
https://doi.org/10.1039/c5ra23949d
https://doi.org/10.1039/c5ra23949d