Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Prakash T. Parvatkar"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract The synthesis of tetracyclic indole alkaloid (±)-decursivine was accomplished using BINOL-phosphoric acid catalyzed tandem oxidative cyclization as a key step with (bis(trifluoroacetoxy)iodo)benzene (PIFA) as an oxidizing agent. This repres
Externí odkaz:
https://doaj.org/article/bf284895493142748f0f1223c362b9fa
Autor:
Prakash T. Parvatkar, Sharath Kandambeth, Aslam C. Shaikh, Issatay Nadinov, Jun Yin, Vinayak S. Kale, George Healing, Abdul-Hamid Emwas, Osama Shekhah, Husam N. Alshareef, Omar F. Mohammed, Mohamed Eddaoudi
Publikováno v:
Journal of the American Chemical Society. 145:5074-5082
Autor:
Lin Shi, Vinayak S. Kale, Zhengnan Tian, Xiangming Xu, Yongjiu Lei, Sharath Kandambeth, Yizhou Wang, Prakash T. Parvatkar, Osama Shekhah, Mohamed Eddaoudi, Husam N. Alshareef
Publikováno v:
Advanced Functional Materials. 33:2212891
Autor:
Hao Jiang, Norah Sadun Alsadun, Prakash T. Parvatkar, Georges Mouchaham, Vincent Guillerm, Justyna Czaban-Jóźwiak, Prashant M. Bhatt, Aleksander Shkurenko, Mohamed Eddaoudi
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2020, ⟨10.1021/jacs.0c10007⟩
Journal of the American Chemical Society, American Chemical Society, 2020, ⟨10.1021/jacs.0c10007⟩
Herein we report novel mesoporous zirconium-based metal-organic frameworks (MOFs) with zeolitic sodalite (sod) topology. Zr-sod-ZMOF-1 and -2 are constructed based on a novel cantellation design strategy. Distinctly, organic linkers are judiciously d
Autor:
Sharath Kandambeth, Husam N. Alshareef, Zhen Cao, Mohamed Eddaoudi, Wenxi Wang, Jun Ming, Wenli Zhang, Osama Shekhah, Prakash T. Parvatkar, Edy Abou-Hamad, Vinayak S. Kale, Luigi Cavallo
Publikováno v:
ACS Energy Letters. 5:2256-2264
Aqueous zinc-ion batteries and capacitors are potentially competitive grid-scale energy storage devices because of their great features such as safety, environmental friendliness, and low cost. Herein, a completely new phenanthroline covalent organic
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Synthesis of tetracyclic indole alkaloid (±)-decursivine was accomplished through BINOL-phosphoric acid catalyzed tandem oxidative cyclization as a key step with hypervalent bis(trifluoroacetoxy)iodo)benzene (PIFA) as an oxidizing agent. This repres
Autor:
Andrii Monastyrskyi, Jordany R. Maignan, Fabian Brockmeyer, Ami H. Asakawa, Sherwin Mashkouri, Prakash T. Parvatkar, Debora Casandra, Yingzhao Zhao, Dennis E. Kyle, Lili Huang, Roman Manetsch, Vivian Padín-Irizarry, Steven P. Maher, Alexis N. LaCrue, Yana I Sakhno
Publikováno v:
J Med Chem
Preclinical and clinical development of numerous small molecules is prevented by their poor aqueous solubility, limited absorption, and oral bioavailability. Herein, we disclose a general prodrug approach that converts promising lead compounds into a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005b49dd5345b7c5ef1724b0ef0b7f31
https://europepmc.org/articles/PMC8904075/
https://europepmc.org/articles/PMC8904075/
Publikováno v:
Bioorganicmedicinal chemistry letters. 48
Cdc25B phosphatase catalyzes the dephosphorylation and activation of cyclin-dependent kinases 2 (CDK2/CycA) and their overexpression has been reported in cancers. Although Cdc25B has received much attention as a drug target, its flat and featureless
Autor:
Hiroshi Fujii, Mai Tsubamoto, Nobuo Kato, Jiazhi Sun, Toan Khanh Le, Chiemi Matsumi, Prakash T. Parvatkar, Minghua Li, Junko Ohkanda, Taku Watanabe
Publikováno v:
Chemistry – A European Journal. 25:13531-13536
Unusual lipid modification of K-Ras makes Ras-directed cancer therapy a challenging task. Aiming to disrupt electrostatic-driven protein-protein interactions (PPIs) of K-Ras with FTase and GGTase I, a series of bivalent dual inhibitors that recognize
Autor:
Lucius Chiaraviglio, James E. Kirby, Prakash T. Parvatkar, Roman Manetsch, Matthew G Dowgiallo, Chungsik Kim, Kenneth P. Smith
Publikováno v:
SLAS Discov
Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging antimicrobial resistance threat for which few if any therapeutic options remain. Identification of new agents that either inhibit CRE or restore activity of existing antimicrobials is high